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    PMPCA peptidase, mitochondrial processing subunit alpha [ Macaca mulatta (Rhesus monkey) ]

    Gene ID: 721742, updated on 17-Aug-2024

    Summary

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    Official Symbol
    PMPCAprovided by VGNC
    Official Full Name
    peptidase, mitochondrial processing subunit alphaprovided by VGNC
    Primary source
    VGNC:VGNC:76062
    See related
    Ensembl:ENSMMUG00000003098
    Gene type
    protein coding
    RefSeq status
    PROVISIONAL
    Organism
    Macaca mulatta
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Cercopithecidae; Cercopithecinae; Macaca
    Orthologs
    human mouse all
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    Genomic context

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    See PMPCA in Genome Data Viewer
    Location:
    chromosome: 15
    Exon count:
    13
    Annotation release Status Assembly Chr Location
    103 current Mmul_10 (GCF_003339765.1) 15 NC_041768.1 (1826516..1840415, complement)
    102 previous assembly Mmul_8.0.1 (GCF_000772875.2) 15 NC_027907.1 (1907656..1921568, complement)

    Chromosome 15 - NC_041768.1Genomic Context describing neighboring genes Neighboring gene chromosome 15 C9orf163 homolog Neighboring gene SEC16 homolog A, endoplasmic reticulum export factor Neighboring gene inositol polyphosphate-5-phosphatase E Neighboring gene endosome associated trafficking regulator 1 Neighboring gene small nuclear RNA activating complex polypeptide 4

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. A new rhesus macaque assembly and annotation for next-generation sequencing analyses. Zimin AV, et al. Biol Direct, 2014 Oct 14. PMID 25319552, Free PMC Article
    2. Manual GO annotation of predictive protein signatures: the InterPro approach to GO curation. Burge S, et al. Database (Oxford), 2012. PMID 22301074, Free PMC Article
    3. TreeGrafter: phylogenetic tree-based annotation of proteins with Gene Ontology terms and other annotations. Tang H, et al. Bioinformatics, 2019 Feb 1. PMID 30032202, Free PMC Article

    GeneRIFs: Gene References Into Functions

    General gene information

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    Markers

    Homology

    Gene Ontology Provided by RefSeq

    Function Evidence Code Pubs
    enables metal ion binding IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    enables metalloendopeptidase activity IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    Process Evidence Code Pubs
    involved_in protein processing involved in protein targeting to mitochondrion IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    Component Evidence Code Pubs
    located_in mitochondrion IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 

    General protein information

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    Preferred Names
    mitochondrial-processing peptidase subunit alpha
    Names
    peptidase, mitochondrial processing alpha subunit
    NP_001252632.1
    XP_014971816.1

    NCBI Reference Sequences (RefSeq)

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    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_001265703.1 → NP_001252632.1  mitochondrial-processing peptidase subunit alpha

      See identical proteins and their annotated locations for NP_001252632.1

      Status: PROVISIONAL

      Source sequence(s)
      JV667276
      UniProtKB/TrEMBL
      F7DRX8, H9EVM7, I2CYA4
      Related
      ENSMMUP00000004138.2, ENSMMUT00000004388.3
      Conserved Domains (3) summary
      COG0612
      Location:65 → 504
      PqqL; Predicted Zn-dependent peptidase [General function prediction only]
      pfam00675
      Location:78 → 227
      Peptidase_M16; Insulinase (Peptidase family M16)
      pfam05193
      Location:232 → 431
      Peptidase_M16_C; Peptidase M16 inactive domain

    RefSeqs of Annotated Genomes: Macaca mulatta Annotation Release 103 details...Open this link in a new tab

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference Mmul_10 Primary Assembly

    Genomic

    1. NC_041768.1 Reference Mmul_10 Primary Assembly

      Range
      1826516..1840415 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_015116330.2 → XP_014971816.1  mitochondrial-processing peptidase subunit alpha isoform X1

      Conserved Domains (3) summary
      COG0612
      Location:47 → 404
      PqqL; Predicted Zn-dependent peptidase [General function prediction only]
      pfam00675
      Location:47 → 127
      Peptidase_M16; Insulinase (Peptidase family M16)
      pfam05193
      Location:132 → 331
      Peptidase_M16_C; Peptidase M16 inactive domain
    Nucleotide Protein
    Heading Accession and Version

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