NLRP7 NLR family pyrin domain containing 7 [Macaca mulatta (Rhesus monkey)] - Gene

Summary

Official Symbol: NLRP7provided by VGNC
Official Full Name: NLR family pyrin domain containing 7provided by VGNC
Primary source: VGNC:VGNC:75236
See related: Ensembl:ENSMMUG00000005266
Gene type: protein coding
RefSeq status: PROVISIONAL
Organism: Macaca mulatta
Lineage: Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Cercopithecidae; Cercopithecinae; Macaca
Orthologs: human all
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Genomic context

Location:: chromosome: 19

Exon count:: 13

Annotation release	Status	Assembly	Chr	Location
103	current	Mmul_10 (GCF_003339765.1)	19	NC_041772.1 (54653984..54680068, complement)
102	previous assembly	Mmul_8.0.1 (GCF_000772875.2)	19	NC_027911.1 (50134232..50155254, complement)

Chromosome 19 - NC_041772.1 Genomic Context describing neighboring genes

Genomic regions, transcripts, and products

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Go to reference sequence details

Genomic Sequence:

Go to nucleotide: Graphics FASTA GenBank

Bibliography

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GeneRIFs: Gene References Into Functions

What's a GeneRIF?

Submit: New GeneRIF Correction

General gene information

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Gene Ontology Provided by RefSeq

Function	Evidence Code	Pubs
enables protein binding	IEA Inferred from Electronic Annotation more info	PubMed

Process	Evidence Code	Pubs
involved_in negative regulation of interleukin-1 beta production	IEA Inferred from Electronic Annotation more info	PubMed
involved_in regulation of inflammatory response	IEA Inferred from Electronic Annotation more info	PubMed

Component	Evidence Code	Pubs
located_in cytoplasm	IEA Inferred from Electronic Annotation more info	PubMed

General protein information

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Preferred Names: NACHT, LRR and PYD domains-containing protein 7

Names: NACHT, leucine rich repeat and PYD containing 7

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

NM_001114353.1 → NP_001107825.1 NACHT, LRR and PYD domains-containing protein 7 isoform 1

See identical proteins and their annotated locations for NP_001107825.1

Status: PROVISIONAL

Source sequence(s)

EU344969

UniProtKB/TrEMBL

B0FPF2, G7NN74

Related

ENSMMUP00000031445.3, ENSMMUT00000038345.3

Conserved Domains (5) summary

COG1100
Location:172 → 256

Gem1; GTPase SAR1 family domain [General function prediction only]

cd00116
Location:734 → 986

LRR_RI; Leucine-rich repeats (LRRs), ribonuclease inhibitor (RI)-like subfamily. LRRs are 20-29 residue sequence motifs present in many proteins that participate in protein-protein interactions and have different functions and cellular locations. LRRs correspond ...

cd08320
Location:10 → 93

Pyrin_NALPs; Pyrin death domain found in NALP proteins

sd00033
Location:735 → 762

LRR_RI; leucine-rich repeat [structural motif]

pfam05729
Location:172 → 340

NACHT; NACHT domain
NM_001114354.1 → NP_001107826.1 NACHT, LRR and PYD domains-containing protein 7 isoform 2

See identical proteins and their annotated locations for NP_001107826.1

Status: PROVISIONAL

Source sequence(s)

EU344970

UniProtKB/TrEMBL

B0FPF3, G7NN74

Related

ENSMMUP00000006967.4, ENSMMUT00000007412.4

Conserved Domains (5) summary

COG1100
Location:172 → 256

Gem1; GTPase SAR1 family domain [General function prediction only]

cd00116
Location:757 → 940

LRR_RI; Leucine-rich repeats (LRRs), ribonuclease inhibitor (RI)-like subfamily. LRRs are 20-29 residue sequence motifs present in many proteins that participate in protein-protein interactions and have different functions and cellular locations. LRRs correspond ...

cd08320
Location:10 → 93

Pyrin_NALPs; Pyrin death domain found in NALP proteins

sd00033
Location:763 → 790

LRR_RI; leucine-rich repeat [structural motif]

pfam05729
Location:172 → 340

NACHT; NACHT domain

RefSeqs of Annotated Genomes: Macaca mulatta Annotation Release 103 details...

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference Mmul_10 Primary Assembly

Genomic

NC_041772.1 Reference Mmul_10 Primary Assembly

Range

54653984..54680068 complement

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GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

XM_028838358.1 → XP_028694191.1 NACHT, LRR and PYD domains-containing protein 7 isoform X1

UniProtKB/TrEMBL

G7NN74

Conserved Domains (4) summary

cd08320
Location:10 → 93

Pyrin_NALPs; Pyrin death domain found in NALP proteins

sd00033
Location:788 → 815

LRR_RI; leucine-rich repeat [structural motif]

pfam05729
Location:197 → 365

NACHT; NACHT domain

cl29113
Location:786 → 1022

LRR_RI; Leucine-rich repeats (LRRs), ribonuclease inhibitor (RI)-like subfamily. LRRs are 20-29 residue sequence motifs present in many proteins that participate in protein-protein interactions and have different functions and cellular locations. LRRs correspond ...
XM_028838355.1 → XP_028694188.1 NACHT, LRR and PYD domains-containing protein 7 isoform X3

UniProtKB/TrEMBL

F7H5K8, G7NN74

Conserved Domains (4) summary

cd08320
Location:10 → 93

Pyrin_NALPs; Pyrin death domain found in NALP proteins

sd00033
Location:735 → 762

LRR_RI; leucine-rich repeat [structural motif]

pfam05729
Location:172 → 340

NACHT; NACHT domain

cl29113
Location:733 → 969

LRR_RI; Leucine-rich repeats (LRRs), ribonuclease inhibitor (RI)-like subfamily. LRRs are 20-29 residue sequence motifs present in many proteins that participate in protein-protein interactions and have different functions and cellular locations. LRRs correspond ...
XM_028838356.1 → XP_028694189.1 NACHT, LRR and PYD domains-containing protein 7 isoform X4

UniProtKB/TrEMBL

G7NN74

Conserved Domains (4) summary

cd08320
Location:10 → 93

Pyrin_NALPs; Pyrin death domain found in NALP proteins

sd00033
Location:788 → 815

LRR_RI; leucine-rich repeat [structural motif]

pfam05729
Location:197 → 365

NACHT; NACHT domain

cl29113
Location:782 → 965

LRR_RI; Leucine-rich repeats (LRRs), ribonuclease inhibitor (RI)-like subfamily. LRRs are 20-29 residue sequence motifs present in many proteins that participate in protein-protein interactions and have different functions and cellular locations. LRRs correspond ...
XM_028838354.1 → XP_028694187.1 NACHT, LRR and PYD domains-containing protein 7 isoform X1

UniProtKB/TrEMBL

G7NN74

Conserved Domains (4) summary

cd08320
Location:10 → 93

Pyrin_NALPs; Pyrin death domain found in NALP proteins

sd00033
Location:788 → 815

LRR_RI; leucine-rich repeat [structural motif]

pfam05729
Location:197 → 365

NACHT; NACHT domain

cl29113
Location:786 → 1022

LRR_RI; Leucine-rich repeats (LRRs), ribonuclease inhibitor (RI)-like subfamily. LRRs are 20-29 residue sequence motifs present in many proteins that participate in protein-protein interactions and have different functions and cellular locations. LRRs correspond ...
XM_028838359.1 → XP_028694192.1 NACHT, LRR and PYD domains-containing protein 7 isoform X2

UniProtKB/TrEMBL

G7NN74

Conserved Domains (4) summary

cd08320
Location:10 → 93

Pyrin_NALPs; Pyrin death domain found in NALP proteins

sd00033
Location:763 → 790

LRR_RI; leucine-rich repeat [structural motif]

pfam05729
Location:172 → 340

NACHT; NACHT domain

cl29113
Location:761 → 997

LRR_RI; Leucine-rich repeats (LRRs), ribonuclease inhibitor (RI)-like subfamily. LRRs are 20-29 residue sequence motifs present in many proteins that participate in protein-protein interactions and have different functions and cellular locations. LRRs correspond ...
XM_028838357.1 → XP_028694190.1 NACHT, LRR and PYD domains-containing protein 7 isoform X5

UniProtKB/TrEMBL

F7BIW5, G7NN74

Conserved Domains (4) summary

cd08320
Location:10 → 93

Pyrin_NALPs; Pyrin death domain found in NALP proteins

sd00033
Location:763 → 790

LRR_RI; leucine-rich repeat [structural motif]

pfam05729
Location:172 → 340

NACHT; NACHT domain

cl29113
Location:757 → 940

LRR_RI; Leucine-rich repeats (LRRs), ribonuclease inhibitor (RI)-like subfamily. LRRs are 20-29 residue sequence motifs present in many proteins that participate in protein-protein interactions and have different functions and cellular locations. LRRs correspond ...
XM_015124865.2 → XP_014980351.2 NACHT, LRR and PYD domains-containing protein 7 isoform X2

UniProtKB/TrEMBL

G7NN74

Conserved Domains (4) summary

cd08320
Location:10 → 93

Pyrin_NALPs; Pyrin death domain found in NALP proteins

sd00033
Location:763 → 790

LRR_RI; leucine-rich repeat [structural motif]

pfam05729
Location:172 → 340

NACHT; NACHT domain

cl29113
Location:761 → 997

LRR_RI; Leucine-rich repeats (LRRs), ribonuclease inhibitor (RI)-like subfamily. LRRs are 20-29 residue sequence motifs present in many proteins that participate in protein-protein interactions and have different functions and cellular locations. LRRs correspond ...