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    DMPK DM1 protein kinase [ Macaca mulatta (Rhesus monkey) ]

    Gene ID: 715328, updated on 5-Mar-2024

    Summary

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    Gene symbol
    DMPK
    Gene description
    DM1 protein kinase
    See related
    Ensembl:ENSMMUG00000016457
    Gene type
    protein coding
    RefSeq status
    PROVISIONAL
    Organism
    Macaca mulatta
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Cercopithecidae; Cercopithecinae; Macaca
    Orthologs
    human mouse all
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    Genomic context

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    See DMPK in Genome Data Viewer
    Location:
    chromosome: 19
    Exon count:
    15
    Annotation release Status Assembly Chr Location
    103 current Mmul_10 (GCF_003339765.1) 19 NC_041772.1 (45852447..45865367, complement)
    102 previous assembly Mmul_8.0.1 (GCF_000772875.2) 19 NC_027911.1 (41128042..41140211, complement)

    Chromosome 19 - NC_041772.1Genomic Context describing neighboring genes Neighboring gene meiosis initiator Neighboring gene SIX homeobox 5 Neighboring gene DM1 locus, WD repeat containing Neighboring gene radial spoke head 6 homolog A

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. A new rhesus macaque assembly and annotation for next-generation sequencing analyses. Zimin AV, et al. Biol Direct, 2014 Oct 14. PMID 25319552, Free PMC Article
    2. Manual GO annotation of predictive protein signatures: the InterPro approach to GO curation. Burge S, et al. Database (Oxford), 2012. PMID 22301074, Free PMC Article
    3. TreeGrafter: phylogenetic tree-based annotation of proteins with Gene Ontology terms and other annotations. Tang H, et al. Bioinformatics, 2019 Feb 1. PMID 30032202, Free PMC Article

    GeneRIFs: Gene References Into Functions

    General gene information

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    Markers

    Homology

    Gene Ontology Provided by RefSeq

    Function Evidence Code Pubs
    enables ATP binding IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    enables protein serine/threonine kinase activity IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    Process Evidence Code Pubs
    involved_in actomyosin structure organization IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    involved_in peptidyl-threonine phosphorylation IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    Component Evidence Code Pubs
    located_in cytoplasm IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    located_in cytoskeleton IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 

    General protein information

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    Preferred Names
    myotonin-protein kinase
    Names
    dystrophia myotonica protein kinase
    NP_001247497.1
    XP_014979613.1
    XP_014979614.1
    XP_014979615.1
    XP_014979616.1
    XP_014979619.1
    XP_028694305.1
    XP_028694306.1
    XP_028694307.1
    XP_028694308.1
    XP_028694309.1

    NCBI Reference Sequences (RefSeq)

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    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_001260568.1 → NP_001247497.1  myotonin-protein kinase

      See identical proteins and their annotated locations for NP_001247497.1

      Status: PROVISIONAL

      Source sequence(s)
      JV044803
      UniProtKB/TrEMBL
      F6Z8J0, F7GBZ8
      Related
      ENSMMUP00000021621.2, ENSMMUT00000023112.4
      Conserved Domains (3) summary
      pfam08826
      Location:470 → 530
      DMPK_coil; DMPK coiled coil domain like
      smart00220
      Location:71 → 339
      S_TKc; Serine/Threonine protein kinases, catalytic domain
      cd05597
      Location:69 → 406
      STKc_DMPK_like; Catalytic domain of Myotonic Dystrophy protein kinase (DMPK)-like Serine/Threonine Kinases

    RefSeqs of Annotated Genomes: Macaca mulatta Annotation Release 103 details...Open this link in a new tab

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference Mmul_10 Primary Assembly

    Genomic

    1. NC_041772.1 Reference Mmul_10 Primary Assembly

      Range
      45852447..45865367 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_028838474.1 → XP_028694307.1  myotonin-protein kinase isoform X6

      Conserved Domains (1) summary
      cl21453
      Location:69 → 356
      PKc_like; Protein Kinases, catalytic domain

    2. XM_028838473.1 → XP_028694306.1  myotonin-protein kinase isoform X2

      Conserved Domains (1) summary
      cd05597
      Location:69 → 401
      STKc_DMPK_like; Catalytic domain of Myotonic Dystrophy protein kinase (DMPK)-like Serine/Threonine Kinases

    3. XM_015124128.2 → XP_014979614.1  myotonin-protein kinase isoform X4

      UniProtKB/TrEMBL
      F6Z8J0
      Conserved Domains (3) summary
      pfam08826
      Location:465 → 525
      DMPK_coil; DMPK coiled coil domain like
      smart00220
      Location:71 → 339
      S_TKc; Serine/Threonine protein kinases, catalytic domain
      cd05597
      Location:69 → 401
      STKc_DMPK_like; Catalytic domain of Myotonic Dystrophy protein kinase (DMPK)-like Serine/Threonine Kinases

    4. XM_015124129.2 → XP_014979615.1  myotonin-protein kinase isoform X5

      UniProtKB/TrEMBL
      F6Z8J0, H9FQT3
      Conserved Domains (3) summary
      pfam08826
      Location:465 → 525
      DMPK_coil; DMPK coiled coil domain like
      smart00220
      Location:71 → 339
      S_TKc; Serine/Threonine protein kinases, catalytic domain
      cd05597
      Location:69 → 401
      STKc_DMPK_like; Catalytic domain of Myotonic Dystrophy protein kinase (DMPK)-like Serine/Threonine Kinases

    5. XM_015124130.2 → XP_014979616.1  myotonin-protein kinase isoform X8

      Conserved Domains (3) summary
      pfam08826
      Location:411 → 440
      DMPK_coil; DMPK coiled coil domain like
      smart00220
      Location:71 → 339
      S_TKc; Serine/Threonine protein kinases, catalytic domain
      cd05597
      Location:69 → 406
      STKc_DMPK_like; Catalytic domain of Myotonic Dystrophy protein kinase (DMPK)-like Serine/Threonine Kinases

    6. XM_028838475.1 → XP_028694308.1  myotonin-protein kinase isoform X7

      UniProtKB/TrEMBL
      F7GBY5
      Conserved Domains (1) summary
      cd05597
      Location:69 → 406
      STKc_DMPK_like; Catalytic domain of Myotonic Dystrophy protein kinase (DMPK)-like Serine/Threonine Kinases

    7. XM_028838476.1 → XP_028694309.1  myotonin-protein kinase isoform X9

      UniProtKB/TrEMBL
      F6Z8J0
      Conserved Domains (1) summary
      cd05597
      Location:69 → 406
      STKc_DMPK_like; Catalytic domain of Myotonic Dystrophy protein kinase (DMPK)-like Serine/Threonine Kinases

    8. XM_028838472.1 → XP_028694305.1  myotonin-protein kinase isoform X1

      Conserved Domains (1) summary
      cd05597
      Location:69 → 406
      STKc_DMPK_like; Catalytic domain of Myotonic Dystrophy protein kinase (DMPK)-like Serine/Threonine Kinases

    9. XM_015124127.2 → XP_014979613.1  myotonin-protein kinase isoform X3

      UniProtKB/TrEMBL
      F6Z8J0, H9FQT4
      Conserved Domains (3) summary
      pfam08826
      Location:470 → 530
      DMPK_coil; DMPK coiled coil domain like
      smart00220
      Location:71 → 339
      S_TKc; Serine/Threonine protein kinases, catalytic domain
      cd05597
      Location:69 → 406
      STKc_DMPK_like; Catalytic domain of Myotonic Dystrophy protein kinase (DMPK)-like Serine/Threonine Kinases

    10. XM_015124133.2 → XP_014979619.1  myotonin-protein kinase isoform X10

      UniProtKB/TrEMBL
      F7GBY5
      Conserved Domains (3) summary
      pfam08826
      Location:496 → 556
      DMPK_coil; DMPK coiled coil domain like
      smart00220
      Location:97 → 365
      S_TKc; Serine/Threonine protein kinases, catalytic domain
      cd05597
      Location:95 → 432
      STKc_DMPK_like; Catalytic domain of Myotonic Dystrophy protein kinase (DMPK)-like Serine/Threonine Kinases
    Nucleotide Protein
    Heading Accession and Version

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