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    PTPRS protein tyrosine phosphatase receptor type S [ Macaca mulatta (Rhesus monkey) ]

    Gene ID: 574274, updated on 17-Aug-2024

    Summary

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    Official Symbol
    PTPRSprovided by VGNC
    Official Full Name
    protein tyrosine phosphatase receptor type Sprovided by VGNC
    Primary source
    VGNC:VGNC:76622
    See related
    Ensembl:ENSMMUG00000011962
    Gene type
    protein coding
    RefSeq status
    MODEL
    Organism
    Macaca mulatta
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Cercopithecidae; Cercopithecinae; Macaca
    Orthologs
    human mouse all
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    Genomic context

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    See PTPRS in Genome Data Viewer
    Location:
    chromosome: 19
    Exon count:
    38
    Annotation release Status Assembly Chr Location
    103 current Mmul_10 (GCF_003339765.1) 19 NC_041772.1 (5137470..5273453, complement)
    102 previous assembly Mmul_8.0.1 (GCF_000772875.2) 19 NC_027911.1 (5364945..5504116, complement)

    Chromosome 19 - NC_041772.1Genomic Context describing neighboring genes Neighboring gene ubiquitin like with PHD and ring finger domains 1 Neighboring gene lysine demethylase 4B Neighboring gene translation initiation factor IF-2-like Neighboring gene 60S ribosomal protein L32 pseudogene Neighboring gene uncharacterized LOC114674029 Neighboring gene zinc and ring finger 4

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. Elevated gene expression levels distinguish human from non-human primate brains. Cáceres M, et al. Proc Natl Acad Sci U S A, 2003 Oct 28. PMID 14557539, Free PMC Article
    2. A new rhesus macaque assembly and annotation for next-generation sequencing analyses. Zimin AV, et al. Biol Direct, 2014 Oct 14. PMID 25319552, Free PMC Article
    3. Manual GO annotation of predictive protein signatures: the InterPro approach to GO curation. Burge S, et al. Database (Oxford), 2012. PMID 22301074, Free PMC Article

    GeneRIFs: Gene References Into Functions

    General gene information

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    Markers

    Homology

    Gene Ontology Provided by RefSeq

    Function Evidence Code Pubs
    enables protein binding IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    enables protein tyrosine phosphatase activity IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    Process Evidence Code Pubs
    involved_in protein dephosphorylation IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 

    General protein information

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    Preferred Names
    receptor-type tyrosine-protein phosphatase S
    XP_014978045.2
    XP_014978047.2
    XP_014978049.2
    XP_014978050.2
    XP_014978051.1
    XP_014978055.2
    XP_014978056.2
    XP_028695360.1
    XP_028695361.1
    XP_028695362.1
    XP_028695363.1

    NCBI Reference Sequences (RefSeq)

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    RefSeqs of Annotated Genomes: Macaca mulatta Annotation Release 103 details...Open this link in a new tab

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference Mmul_10 Primary Assembly

    Genomic

    1. NC_041772.1 Reference Mmul_10 Primary Assembly

      Range
      5137470..5273453 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_015122563.2 → XP_014978049.2  receptor-type tyrosine-protein phosphatase S isoform X4

      UniProtKB/TrEMBL
      F7HG97, F7HGA1, H9FXU8
      Related
      ENSMMUP00000015692.4, ENSMMUT00000016757.4
      Conserved Domains (8) summary
      cd00063
      Location:319 → 408
      FN3; Fibronectin type 3 domain; One of three types of internal repeats found in the plasma protein fibronectin. Its tenth fibronectin type III repeat contains an RGD cell recognition sequence in a flexible loop between 2 strands. Approximately 2% of all ...
      cd14625
      Location:1348 → 1629
      R-PTPc-S-1; catalytic domain of receptor-type tyrosine-protein phosphatase S, repeat 1
      cd14627
      Location:1631 → 1920
      R-PTP-S-2; PTP-like domain of receptor-type tyrosine-protein phosphatase S, repeat 2
      pfam07679
      Location:33 → 124
      I-set; Immunoglobulin I-set domain
      pfam18861
      Location:1186 → 1285
      PTP_tm; Transmembrane domain of protein tyrosine phosphatase, receptor type J
      cd00096
      Location:33 → 36
      Ig; Ig strand A [structural motif]
      cd05738
      Location:137 → 226
      IgI_2_RPTP_IIa_LAR_like; Second immunoglobulin (Ig)-like domain of the receptor protein tyrosine phosphatase (RPTP)-F; member of the I-set of IgSF domains
      cd05739
      Location:235 → 316
      IgI_3_RPTP_IIa_LAR_like; Third immunoglobulin (Ig)-like domain of the receptor protein tyrosine phosphatase (RPTP)-F (also known as LAR), type IIa; member of the I-set of IgSF domains

    2. XM_015122561.2 → XP_014978047.2  receptor-type tyrosine-protein phosphatase S isoform X2

      UniProtKB/TrEMBL
      F7HGA1
      Conserved Domains (8) summary
      cd00063
      Location:319 → 408
      FN3; Fibronectin type 3 domain; One of three types of internal repeats found in the plasma protein fibronectin. Its tenth fibronectin type III repeat contains an RGD cell recognition sequence in a flexible loop between 2 strands. Approximately 2% of all ...
      cd14625
      Location:1357 → 1638
      R-PTPc-S-1; catalytic domain of receptor-type tyrosine-protein phosphatase S, repeat 1
      cd14627
      Location:1640 → 1929
      R-PTP-S-2; PTP-like domain of receptor-type tyrosine-protein phosphatase S, repeat 2
      pfam07679
      Location:33 → 124
      I-set; Immunoglobulin I-set domain
      pfam18861
      Location:1195 → 1294
      PTP_tm; Transmembrane domain of protein tyrosine phosphatase, receptor type J
      cd00096
      Location:33 → 36
      Ig; Ig strand A [structural motif]
      cd05738
      Location:137 → 226
      IgI_2_RPTP_IIa_LAR_like; Second immunoglobulin (Ig)-like domain of the receptor protein tyrosine phosphatase (RPTP)-F; member of the I-set of IgSF domains
      cd05739
      Location:235 → 316
      IgI_3_RPTP_IIa_LAR_like; Third immunoglobulin (Ig)-like domain of the receptor protein tyrosine phosphatase (RPTP)-F (also known as LAR), type IIa; member of the I-set of IgSF domains

    3. XM_028839528.1 → XP_028695361.1  receptor-type tyrosine-protein phosphatase S isoform X3

      UniProtKB/TrEMBL
      F7HGA1
      Conserved Domains (8) summary
      cd00063
      Location:323 → 412
      FN3; Fibronectin type 3 domain; One of three types of internal repeats found in the plasma protein fibronectin. Its tenth fibronectin type III repeat contains an RGD cell recognition sequence in a flexible loop between 2 strands. Approximately 2% of all ...
      cd14625
      Location:1352 → 1633
      R-PTPc-S-1; catalytic domain of receptor-type tyrosine-protein phosphatase S, repeat 1
      cd14627
      Location:1635 → 1924
      R-PTP-S-2; PTP-like domain of receptor-type tyrosine-protein phosphatase S, repeat 2
      pfam07679
      Location:33 → 124
      I-set; Immunoglobulin I-set domain
      pfam18861
      Location:1190 → 1289
      PTP_tm; Transmembrane domain of protein tyrosine phosphatase, receptor type J
      cd00096
      Location:33 → 36
      Ig; Ig strand A [structural motif]
      cd05738
      Location:137 → 226
      IgI_2_RPTP_IIa_LAR_like; Second immunoglobulin (Ig)-like domain of the receptor protein tyrosine phosphatase (RPTP)-F; member of the I-set of IgSF domains
      cd05739
      Location:239 → 320
      IgI_3_RPTP_IIa_LAR_like; Third immunoglobulin (Ig)-like domain of the receptor protein tyrosine phosphatase (RPTP)-F (also known as LAR), type IIa; member of the I-set of IgSF domains

    4. XM_015122559.2 → XP_014978045.2  receptor-type tyrosine-protein phosphatase S isoform X1

      UniProtKB/TrEMBL
      F7HGA1
      Conserved Domains (8) summary
      cd00063
      Location:323 → 412
      FN3; Fibronectin type 3 domain; One of three types of internal repeats found in the plasma protein fibronectin. Its tenth fibronectin type III repeat contains an RGD cell recognition sequence in a flexible loop between 2 strands. Approximately 2% of all ...
      cd14625
      Location:1361 → 1642
      R-PTPc-S-1; catalytic domain of receptor-type tyrosine-protein phosphatase S, repeat 1
      cd14627
      Location:1644 → 1933
      R-PTP-S-2; PTP-like domain of receptor-type tyrosine-protein phosphatase S, repeat 2
      pfam07679
      Location:33 → 124
      I-set; Immunoglobulin I-set domain
      pfam18861
      Location:1199 → 1298
      PTP_tm; Transmembrane domain of protein tyrosine phosphatase, receptor type J
      cd00096
      Location:33 → 36
      Ig; Ig strand A [structural motif]
      cd05738
      Location:137 → 226
      IgI_2_RPTP_IIa_LAR_like; Second immunoglobulin (Ig)-like domain of the receptor protein tyrosine phosphatase (RPTP)-F; member of the I-set of IgSF domains
      cd05739
      Location:239 → 320
      IgI_3_RPTP_IIa_LAR_like; Third immunoglobulin (Ig)-like domain of the receptor protein tyrosine phosphatase (RPTP)-F (also known as LAR), type IIa; member of the I-set of IgSF domains

    5. XM_028839527.1 → XP_028695360.1  receptor-type tyrosine-protein phosphatase S isoform X1

      UniProtKB/TrEMBL
      F7HGA1
      Related
      ENSMMUP00000015690.4, ENSMMUT00000016755.4
      Conserved Domains (8) summary
      cd00063
      Location:323 → 412
      FN3; Fibronectin type 3 domain; One of three types of internal repeats found in the plasma protein fibronectin. Its tenth fibronectin type III repeat contains an RGD cell recognition sequence in a flexible loop between 2 strands. Approximately 2% of all ...
      cd14625
      Location:1361 → 1642
      R-PTPc-S-1; catalytic domain of receptor-type tyrosine-protein phosphatase S, repeat 1
      cd14627
      Location:1644 → 1933
      R-PTP-S-2; PTP-like domain of receptor-type tyrosine-protein phosphatase S, repeat 2
      pfam07679
      Location:33 → 124
      I-set; Immunoglobulin I-set domain
      pfam18861
      Location:1199 → 1298
      PTP_tm; Transmembrane domain of protein tyrosine phosphatase, receptor type J
      cd00096
      Location:33 → 36
      Ig; Ig strand A [structural motif]
      cd05738
      Location:137 → 226
      IgI_2_RPTP_IIa_LAR_like; Second immunoglobulin (Ig)-like domain of the receptor protein tyrosine phosphatase (RPTP)-F; member of the I-set of IgSF domains
      cd05739
      Location:239 → 320
      IgI_3_RPTP_IIa_LAR_like; Third immunoglobulin (Ig)-like domain of the receptor protein tyrosine phosphatase (RPTP)-F (also known as LAR), type IIa; member of the I-set of IgSF domains

    6. XM_028839530.1 → XP_028695363.1  receptor-type tyrosine-protein phosphatase S isoform X10

      UniProtKB/TrEMBL
      H9FXV1
      Conserved Domains (8) summary
      cd00063
      Location:319 → 408
      FN3; Fibronectin type 3 domain; One of three types of internal repeats found in the plasma protein fibronectin. Its tenth fibronectin type III repeat contains an RGD cell recognition sequence in a flexible loop between 2 strands. Approximately 2% of all ...
      cd14625
      Location:939 → 1220
      R-PTPc-S-1; catalytic domain of receptor-type tyrosine-protein phosphatase S, repeat 1
      cd14627
      Location:1222 → 1511
      R-PTP-S-2; PTP-like domain of receptor-type tyrosine-protein phosphatase S, repeat 2
      pfam07679
      Location:33 → 124
      I-set; Immunoglobulin I-set domain
      pfam18861
      Location:777 → 876
      PTP_tm; Transmembrane domain of protein tyrosine phosphatase, receptor type J
      cd00096
      Location:36 → 39
      Ig; Ig strand A [structural motif]
      cd05738
      Location:137 → 226
      IgI_2_RPTP_IIa_LAR_like; Second immunoglobulin (Ig)-like domain of the receptor protein tyrosine phosphatase (RPTP)-F; member of the I-set of IgSF domains
      cd05739
      Location:235 → 316
      IgI_3_RPTP_IIa_LAR_like; Third immunoglobulin (Ig)-like domain of the receptor protein tyrosine phosphatase (RPTP)-F (also known as LAR), type IIa; member of the I-set of IgSF domains

    7. XM_015122565.2 → XP_014978051.1  receptor-type tyrosine-protein phosphatase S isoform X7

      UniProtKB/TrEMBL
      A0A5F7ZD35
      Conserved Domains (5) summary
      cd05739
      Location:3 → 71
      Ig3_RPTP_IIa_LAR_like; Third immunoglobulin (Ig)-like domain of the receptor protein tyrosine phosphatase (RPTP)-F, also known as LAR
      smart00194
      Location:1136 → 1391
      PTPc; Protein tyrosine phosphatase, catalytic domain
      smart00410
      Location:1 → 72
      IG_like; Immunoglobulin like
      cd00047
      Location:1162 → 1391
      PTPc; Protein tyrosine phosphatases (PTP) catalyze the dephosphorylation of phosphotyrosine peptides; they regulate phosphotyrosine levels in signal transduction pathways. The depth of the active site cleft renders the enzyme specific for phosphorylated Tyr ...
      cd00063
      Location:76 → 165
      FN3; Fibronectin type 3 domain; One of three types of internal repeats found in the plasma protein fibronectin. Its tenth fibronectin type III repeat contains an RGD cell recognition sequence in a flexible loop between 2 strands. Approximately 2% of all ...

    8. XM_028839529.1 → XP_028695362.1  receptor-type tyrosine-protein phosphatase S isoform X5

      UniProtKB/TrEMBL
      F7HGA1
      Conserved Domains (8) summary
      cd00063
      Location:323 → 412
      FN3; Fibronectin type 3 domain; One of three types of internal repeats found in the plasma protein fibronectin. Its tenth fibronectin type III repeat contains an RGD cell recognition sequence in a flexible loop between 2 strands. Approximately 2% of all ...
      cd14625
      Location:1345 → 1626
      R-PTPc-S-1; catalytic domain of receptor-type tyrosine-protein phosphatase S, repeat 1
      cd14627
      Location:1628 → 1917
      R-PTP-S-2; PTP-like domain of receptor-type tyrosine-protein phosphatase S, repeat 2
      pfam07679
      Location:33 → 124
      I-set; Immunoglobulin I-set domain
      pfam18861
      Location:1199 → 1298
      PTP_tm; Transmembrane domain of protein tyrosine phosphatase, receptor type J
      cd00096
      Location:33 → 36
      Ig; Ig strand A [structural motif]
      cd05738
      Location:137 → 226
      IgI_2_RPTP_IIa_LAR_like; Second immunoglobulin (Ig)-like domain of the receptor protein tyrosine phosphatase (RPTP)-F; member of the I-set of IgSF domains
      cd05739
      Location:239 → 320
      IgI_3_RPTP_IIa_LAR_like; Third immunoglobulin (Ig)-like domain of the receptor protein tyrosine phosphatase (RPTP)-F (also known as LAR), type IIa; member of the I-set of IgSF domains

    9. XM_015122570.2 → XP_014978056.2  receptor-type tyrosine-protein phosphatase S isoform X9

      UniProtKB/TrEMBL
      H9FXV0
      Conserved Domains (6) summary
      cd05739
      Location:246 → 314
      Ig3_RPTP_IIa_LAR_like; Third immunoglobulin (Ig)-like domain of the receptor protein tyrosine phosphatase (RPTP)-F, also known as LAR
      cd00063
      Location:319 → 408
      FN3; Fibronectin type 3 domain; One of three types of internal repeats found in the plasma protein fibronectin. Its tenth fibronectin type III repeat contains an RGD cell recognition sequence in a flexible loop between 2 strands. Approximately 2% of all ...
      cd05738
      Location:152 → 226
      Ig2_RPTP_IIa_LAR_like; Second immunoglobulin (Ig)-like domain of the receptor protein tyrosine phosphatase (RPTP)-F, also known as LAR
      cd14625
      Location:923 → 1204
      R-PTPc-S-1; catalytic domain of receptor-type tyrosine-protein phosphatase S, repeat 1
      cd14627
      Location:1206 → 1495
      R-PTP-S-2; PTP-like domain of receptor-type tyrosine-protein phosphatase S, repeat 2
      pfam07679
      Location:33 → 124
      I-set; Immunoglobulin I-set domain

    10. XM_015122564.2 → XP_014978050.2  receptor-type tyrosine-protein phosphatase S isoform X6

      UniProtKB/TrEMBL
      F7HG94, F7HGA1, I2CXF0
      Related
      ENSMMUP00000015694.4, ENSMMUT00000016759.4
      Conserved Domains (6) summary
      cd05739
      Location:246 → 314
      Ig3_RPTP_IIa_LAR_like; Third immunoglobulin (Ig)-like domain of the receptor protein tyrosine phosphatase (RPTP)-F, also known as LAR
      cd00063
      Location:319 → 408
      FN3; Fibronectin type 3 domain; One of three types of internal repeats found in the plasma protein fibronectin. Its tenth fibronectin type III repeat contains an RGD cell recognition sequence in a flexible loop between 2 strands. Approximately 2% of all ...
      cd05738
      Location:152 → 226
      Ig2_RPTP_IIa_LAR_like; Second immunoglobulin (Ig)-like domain of the receptor protein tyrosine phosphatase (RPTP)-F, also known as LAR
      cd14625
      Location:1332 → 1613
      R-PTPc-S-1; catalytic domain of receptor-type tyrosine-protein phosphatase S, repeat 1
      cd14627
      Location:1615 → 1904
      R-PTP-S-2; PTP-like domain of receptor-type tyrosine-protein phosphatase S, repeat 2
      pfam07679
      Location:33 → 124
      I-set; Immunoglobulin I-set domain

    11. XM_015122569.2 → XP_014978055.2  receptor-type tyrosine-protein phosphatase S isoform X8

      UniProtKB/TrEMBL
      I2CY17
      Related
      ENSMMUP00000015698.4, ENSMMUT00000016763.4
      Conserved Domains (6) summary
      cd05739
      Location:250 → 318
      Ig3_RPTP_IIa_LAR_like; Third immunoglobulin (Ig)-like domain of the receptor protein tyrosine phosphatase (RPTP)-F, also known as LAR
      cd00063
      Location:323 → 412
      FN3; Fibronectin type 3 domain; One of three types of internal repeats found in the plasma protein fibronectin. Its tenth fibronectin type III repeat contains an RGD cell recognition sequence in a flexible loop between 2 strands. Approximately 2% of all ...
      cd05738
      Location:152 → 226
      Ig2_RPTP_IIa_LAR_like; Second immunoglobulin (Ig)-like domain of the receptor protein tyrosine phosphatase (RPTP)-F, also known as LAR
      pfam07679
      Location:33 → 124
      I-set; Immunoglobulin I-set domain
      cd14625
      Location:927 → 1208
      R-PTPc-S-1; catalytic domain of receptor-type tyrosine-protein phosphatase S, repeat 1
      cd14627
      Location:1210 → 1499
      R-PTP-S-2; PTP-like domain of receptor-type tyrosine-protein phosphatase S, repeat 2
    Nucleotide Protein
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