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    ITIH3 inter-alpha-trypsin inhibitor heavy chain 3 [ Macaca mulatta (Rhesus monkey) ]

    Gene ID: 695200, updated on 17-Aug-2024

    Summary

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    Official Symbol
    ITIH3provided by VGNC
    Official Full Name
    inter-alpha-trypsin inhibitor heavy chain 3provided by VGNC
    Primary source
    VGNC:VGNC:73795
    See related
    Ensembl:ENSMMUG00000014522
    Gene type
    protein coding
    RefSeq status
    MODEL
    Organism
    Macaca mulatta
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Cercopithecidae; Cercopithecinae; Macaca
    Orthologs
    human mouse all
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    Genomic context

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    See ITIH3 in Genome Data Viewer
    Location:
    chromosome: 2
    Exon count:
    22
    Annotation release Status Assembly Chr Location
    103 current Mmul_10 (GCF_003339765.1) 2 NC_041755.1 (108974864..108989347)
    102 previous assembly Mmul_8.0.1 (GCF_000772875.2) 2 NC_027894.1 (89370595..89385079, complement)

    Chromosome 2 - NC_041755.1Genomic Context describing neighboring genes Neighboring gene NIMA related kinase 4 Neighboring gene AKT-interacting protein-like Neighboring gene inter-alpha-trypsin inhibitor heavy chain 1 Neighboring gene inter-alpha-trypsin inhibitor heavy chain 4 Neighboring gene musculoskeletal, embryonic nuclear protein 1

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. Manual GO annotation of predictive protein signatures: the InterPro approach to GO curation. Burge S, et al. Database (Oxford), 2012. PMID 22301074, Free PMC Article

    GeneRIFs: Gene References Into Functions

    General gene information

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    Markers

    Homology

    Gene Ontology Provided by RefSeq

    Function Evidence Code Pubs
    enables serine-type endopeptidase inhibitor activity IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    Process Evidence Code Pubs
    involved_in hyaluronan metabolic process IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 

    General protein information

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    Preferred Names
    inter-alpha-trypsin inhibitor heavy chain H3
    Names
    inter-alpha (globulin) inhibitor H3

    NCBI Reference Sequences (RefSeq)

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    RefSeqs of Annotated Genomes: Macaca mulatta Annotation Release 103 details...Open this link in a new tab

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference Mmul_10 Primary Assembly

    Genomic

    1. NC_041755.1 Reference Mmul_10 Primary Assembly

      Range
      108974864..108989347
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_001085463.3 → XP_001085463.1  inter-alpha-trypsin inhibitor heavy chain H3

      UniProtKB/TrEMBL
      F7GAT4, G7ML31
      Related
      ENSMMUP00000019067.3, ENSMMUT00000020371.4
      Conserved Domains (4) summary
      smart00609
      Location:29 → 158
      VIT; Vault protein Inter-alpha-Trypsin domain
      cd01461
      Location:281 → 462
      vWA_interalpha_trypsin_inhibitor; vWA_interalpha trypsin inhibitor (ITI): ITI is a glycoprotein composed of three polypeptides- two heavy chains and one light chain (bikunin). Bikunin confers the protease-inhibitor function while the heavy chains are involved in rendering stability to ...
      TIGR03788
      Location:47 → 613
      marine_srt_targ; marine proteobacterial sortase target protein
      pfam06668
      Location:685 → 872
      ITI_HC_C; Inter-alpha-trypsin inhibitor heavy chain C-terminus
    Nucleotide Protein
    Heading Accession and Version

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