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    FANCM FA complementation group M [ Macaca mulatta (Rhesus monkey) ]

    Gene ID: 702513, updated on 17-Aug-2024

    Summary

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    Official Symbol
    FANCMprovided by VGNC
    Official Full Name
    FA complementation group Mprovided by VGNC
    Primary source
    VGNC:VGNC:72554
    See related
    Ensembl:ENSMMUG00000016513
    Gene type
    protein coding
    RefSeq status
    MODEL
    Organism
    Macaca mulatta
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Cercopithecidae; Cercopithecinae; Macaca
    Orthologs
    human mouse all
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    Genomic context

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    See FANCM in Genome Data Viewer
    Location:
    chromosome: 7
    Exon count:
    23
    Annotation release Status Assembly Chr Location
    103 current Mmul_10 (GCF_003339765.1) 7 NC_041760.1 (107434436..107506267)
    102 previous assembly Mmul_8.0.1 (GCF_000772875.2) 7 NC_027899.1 (107114750..107187717)

    Chromosome 7 - NC_041760.1Genomic Context describing neighboring genes Neighboring gene pre-mRNA processing factor 39 Neighboring gene small nucleolar RNA SNORD127 Neighboring gene FKBP prolyl isomerase 3 Neighboring gene MIS18 binding protein 1 Neighboring gene U6 spliceosomal RNA

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. A new rhesus macaque assembly and annotation for next-generation sequencing analyses. Zimin AV, et al. Biol Direct, 2014 Oct 14. PMID 25319552, Free PMC Article
    2. Manual GO annotation of predictive protein signatures: the InterPro approach to GO curation. Burge S, et al. Database (Oxford), 2012. PMID 22301074, Free PMC Article
    3. TreeGrafter: phylogenetic tree-based annotation of proteins with Gene Ontology terms and other annotations. Tang H, et al. Bioinformatics, 2019 Feb 1. PMID 30032202, Free PMC Article

    GeneRIFs: Gene References Into Functions

    General gene information

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    Markers

    Homology

    Gene Ontology Provided by RefSeq

    Function Evidence Code Pubs
    enables 3'-5' DNA helicase activity IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    enables ATP binding IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    enables four-way junction DNA binding IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    enables four-way junction helicase activity IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    enables nuclease activity IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    Process Evidence Code Pubs
    involved_in double-strand break repair via synthesis-dependent strand annealing IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    involved_in interstrand cross-link repair IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    involved_in replication fork reversal IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 

    General protein information

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    Preferred Names
    Fanconi anemia group M protein
    Names
    Fanconi anemia complementation group M

    NCBI Reference Sequences (RefSeq)

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    RefSeqs of Annotated Genomes: Macaca mulatta Annotation Release 103 details...Open this link in a new tab

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference Mmul_10 Primary Assembly

    Genomic

    1. NC_041760.1 Reference Mmul_10 Primary Assembly

      Range
      107434436..107506267
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_015143628.2 → XP_014999114.2  Fanconi anemia group M protein isoform X1

      UniProtKB/TrEMBL
      A0A5F8AEY5, F6WK00
      Related
      ENSMMUP00000021700.4, ENSMMUT00000023194.4
      Conserved Domains (3) summary
      COG1111
      Location:83 → 608
      MPH1; ERCC4-related helicase [Replication, recombination and repair]
      COG1948
      Location:1814 → 2040
      MUS81; ERCC4-type nuclease [Replication, recombination and repair]
      pfam16783
      Location:675 → 789
      FANCM-MHF_bd; FANCM to MHF binding domain

    2. XM_015143630.2 → XP_014999116.2  Fanconi anemia group M protein isoform X3

      UniProtKB/TrEMBL
      A0A5F8AEY5
      Conserved Domains (4) summary
      COG1111
      Location:83 → 544
      MPH1; ERCC4-related helicase [Replication, recombination and repair]
      COG1948
      Location:1745 → 1971
      MUS81; ERCC4-type nuclease [Replication, recombination and repair]
      pfam16783
      Location:606 → 720
      FANCM-MHF_bd; FANCM to MHF binding domain
      cd18033
      Location:89 → 270
      DEXDc_FANCM; DEAH-box helicase domain of FANCM

    3. XM_028851527.1 → XP_028707360.1  Fanconi anemia group M protein isoform X2

      UniProtKB/TrEMBL
      A0A5F7Z6V4, A0A5F8AEY5
      Related
      ENSMMUP00000061102.1, ENSMMUT00000091254.1
      Conserved Domains (3) summary
      COG1111
      Location:83 → 564
      MPH1; ERCC4-related helicase [Replication, recombination and repair]
      COG1948
      Location:1770 → 1996
      MUS81; ERCC4-type nuclease [Replication, recombination and repair]
      pfam16783
      Location:631 → 745
      FANCM-MHF_bd; FANCM to MHF binding domain

    4. XM_028851528.1 → XP_028707361.1  Fanconi anemia group M protein isoform X4

      UniProtKB/TrEMBL
      F7G0R0
      Conserved Domains (3) summary
      COG1948
      Location:1419 → 1645
      MUS81; ERCC4-type nuclease [Replication, recombination and repair]
      pfam16783
      Location:280 → 394
      FANCM-MHF_bd; FANCM to MHF binding domain
      cd18801
      Location:46 → 194
      SF2_C_FANCM_Hef; C-terminal helicase domain of Fanconi anemia group M family helicases
    Nucleotide Protein
    Heading Accession and Version

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