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    GRIA4 glutamate ionotropic receptor AMPA type subunit 4 [ Macaca mulatta (Rhesus monkey) ]

    Gene ID: 705794, updated on 17-Aug-2024

    Summary

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    Official Symbol
    GRIA4provided by VGNC
    Official Full Name
    glutamate ionotropic receptor AMPA type subunit 4provided by VGNC
    Primary source
    VGNC:VGNC:73274
    Locus tag
    EGK_06846
    See related
    Ensembl:ENSMMUG00000010987
    Gene type
    protein coding
    RefSeq status
    MODEL
    Organism
    Macaca mulatta
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Cercopithecidae; Cercopithecinae; Macaca
    Orthologs
    human mouse all
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    Genomic context

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    See GRIA4 in Genome Data Viewer
    Location:
    chromosome: 14
    Exon count:
    21
    Annotation release Status Assembly Chr Location
    103 current Mmul_10 (GCF_003339765.1) 14 NC_041767.1 (98876001..99249348)
    102 previous assembly Mmul_8.0.1 (GCF_000772875.2) 14 NC_027906.1 (98497538..98873756)

    Chromosome 14 - NC_041767.1Genomic Context describing neighboring genes Neighboring gene caspase recruitment domain-containing protein 17-like Neighboring gene caspase recruitment domain-containing protein 17 Neighboring gene caspase recruitment domain family member 18 Neighboring gene U4 spliceosomal RNA Neighboring gene Myb/SANT DNA binding domain containing 4 with coiled-coils Neighboring gene aminoadipate-semialdehyde dehydrogenase-phosphopantetheinyl transferase Neighboring gene kelch repeat and BTB domain containing 3

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. Manual GO annotation of predictive protein signatures: the InterPro approach to GO curation. Burge S, et al. Database (Oxford), 2012. PMID 22301074, Free PMC Article
    2. TreeGrafter: phylogenetic tree-based annotation of proteins with Gene Ontology terms and other annotations. Tang H, et al. Bioinformatics, 2019 Feb 1. PMID 30032202, Free PMC Article

    GeneRIFs: Gene References Into Functions

    General gene information

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    Markers

    Homology

    Gene Ontology Provided by RefSeq

    Function Evidence Code Pubs
    enables AMPA glutamate receptor activity IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    enables transmitter-gated monoatomic ion channel activity involved in regulation of postsynaptic membrane potential IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    Process Evidence Code Pubs
    involved_in modulation of chemical synaptic transmission IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    involved_in monoatomic ion transport IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    involved_in synaptic transmission, glutamatergic IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    Component Evidence Code Pubs
    part_of AMPA glutamate receptor complex IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    located_in dendritic spine IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    located_in plasma membrane IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    located_in postsynaptic membrane IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 

    General protein information

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    Preferred Names
    glutamate receptor 4
    Names
    glutamate receptor, ionotrophic, AMPA 4

    NCBI Reference Sequences (RefSeq)

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    RefSeqs of Annotated Genomes: Macaca mulatta Annotation Release 103 details...Open this link in a new tab

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference Mmul_10 Primary Assembly

    Genomic

    1. NC_041767.1 Reference Mmul_10 Primary Assembly

      Range
      98876001..99249348
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_015115583.2 → XP_014971069.1  glutamate receptor 4 isoform X1

      UniProtKB/TrEMBL
      I2CT47
      Conserved Domains (2) summary
      cd13727
      Location:414 → 795
      PBP2_iGluR_AMPA_GluR4; The ligand-binding domain of the AMPA (alpha-amino-3-hydroxyl-5-methyl-4-isoxazolepropionic acid) subtype GluR4 of ionotropic glutamate receptors, a member of the type 2 periplasmic binding fold protein superfamily
      cd06388
      Location:28 → 400
      PBP1_iGluR_AMPA_GluR4; N-terminal leucine-isoleucine-valine binding protein (LIVBP)-like domain of the GluR4 subunit of the AMPA receptor

    2. XM_015115581.2 → XP_014971067.1  glutamate receptor 4 isoform X1

      UniProtKB/TrEMBL
      I2CT47
      Conserved Domains (2) summary
      cd13727
      Location:414 → 795
      PBP2_iGluR_AMPA_GluR4; The ligand-binding domain of the AMPA (alpha-amino-3-hydroxyl-5-methyl-4-isoxazolepropionic acid) subtype GluR4 of ionotropic glutamate receptors, a member of the type 2 periplasmic binding fold protein superfamily
      cd06388
      Location:28 → 400
      PBP1_iGluR_AMPA_GluR4; N-terminal leucine-isoleucine-valine binding protein (LIVBP)-like domain of the GluR4 subunit of the AMPA receptor

    3. XM_015115585.2 → XP_014971071.1  glutamate receptor 4 isoform X3

      UniProtKB/TrEMBL
      F7AGS3, I2CT47
      Related
      ENSMMUP00000006497.4, ENSMMUT00000006906.4
      Conserved Domains (2) summary
      cd13727
      Location:414 → 795
      PBP2_iGluR_AMPA_GluR4; The ligand-binding domain of the AMPA (alpha-amino-3-hydroxyl-5-methyl-4-isoxazolepropionic acid) subtype GluR4 of ionotropic glutamate receptors, a member of the type 2 periplasmic binding fold protein superfamily
      cd06388
      Location:28 → 400
      PBP1_iGluR_AMPA_GluR4; N-terminal leucine-isoleucine-valine binding protein (LIVBP)-like domain of the GluR4 subunit of the AMPA receptor

    4. XM_015115582.2 → XP_014971068.1  glutamate receptor 4 isoform X2

      UniProtKB/TrEMBL
      G7NBS5, I2CT47
      Conserved Domains (2) summary
      cd13727
      Location:414 → 795
      PBP2_iGluR_AMPA_GluR4; The ligand-binding domain of the AMPA (alpha-amino-3-hydroxyl-5-methyl-4-isoxazolepropionic acid) subtype GluR4 of ionotropic glutamate receptors, a member of the type 2 periplasmic binding fold protein superfamily
      cd06388
      Location:28 → 400
      PBP1_iGluR_AMPA_GluR4; N-terminal leucine-isoleucine-valine binding protein (LIVBP)-like domain of the GluR4 subunit of the AMPA receptor

    5. XM_015115586.2 → XP_014971072.1  glutamate receptor 4 isoform X4

      UniProtKB/TrEMBL
      A0A5F8A4A5, I2CT47
      Related
      ENSMMUP00000071737.1, ENSMMUT00000084216.1
      Conserved Domains (2) summary
      cd13727
      Location:414 → 795
      PBP2_iGluR_AMPA_GluR4; The ligand-binding domain of the AMPA (alpha-amino-3-hydroxyl-5-methyl-4-isoxazolepropionic acid) subtype GluR4 of ionotropic glutamate receptors, a member of the type 2 periplasmic binding fold protein superfamily
      cd06388
      Location:28 → 400
      PBP1_iGluR_AMPA_GluR4; N-terminal leucine-isoleucine-valine binding protein (LIVBP)-like domain of the GluR4 subunit of the AMPA receptor

    6. XM_015115588.2 → XP_014971074.1  glutamate receptor 4 isoform X5

      UniProtKB/TrEMBL
      A0A5F8A6H9, H9ENK7
      Related
      ENSMMUP00000070896.1, ENSMMUT00000087019.1
      Conserved Domains (1) summary
      cd06388
      Location:28 → 400
      PBP1_iGluR_AMPA_GluR4; N-terminal leucine-isoleucine-valine binding protein (LIVBP)-like domain of the GluR4 subunit of the AMPA receptor

    7. XM_015115584.2 → XP_014971070.1  glutamate receptor 4 isoform X1

      UniProtKB/TrEMBL
      I2CT47
      Conserved Domains (2) summary
      cd13727
      Location:414 → 795
      PBP2_iGluR_AMPA_GluR4; The ligand-binding domain of the AMPA (alpha-amino-3-hydroxyl-5-methyl-4-isoxazolepropionic acid) subtype GluR4 of ionotropic glutamate receptors, a member of the type 2 periplasmic binding fold protein superfamily
      cd06388
      Location:28 → 400
      PBP1_iGluR_AMPA_GluR4; N-terminal leucine-isoleucine-valine binding protein (LIVBP)-like domain of the GluR4 subunit of the AMPA receptor

    RNA

    1. XR_001439691.2 RNA Sequence

    2. XR_003722738.1 RNA Sequence

    Nucleotide Protein
    Heading Accession and Version

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