PLG plasminogen [Macaca mulatta (Rhesus monkey)] - Gene

Summary

Official Symbol: PLGprovided by VGNC
Official Full Name: plasminogenprovided by VGNC
Primary source: VGNC:VGNC:82206
See related: Ensembl:ENSMMUG00000016945
Gene type: protein coding
RefSeq status: PROVISIONAL
Organism: Macaca mulatta
Lineage: Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Cercopithecidae; Cercopithecinae; Macaca
Orthologs: human mouse all
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Genomic context

Location:: chromosome: 4

Exon count:: 19

Annotation release	Status	Assembly	Chr	Location
103	current	Mmul_10 (GCF_003339765.1)	4	NC_041757.1 (9924066..9974322, complement)
102	previous assembly	Mmul_8.0.1 (GCF_000772875.2)	4	NC_027896.1 (161790243..161841642)

Chromosome 4 - NC_041757.1 Genomic Context describing neighboring genes

Genomic regions, transcripts, and products

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Genomic Sequence:

Go to nucleotide: Graphics FASTA GenBank

Bibliography

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GeneRIFs: Gene References Into Functions

What's a GeneRIF?

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General gene information

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Markers

A009P38 (e-PCR)
- UniSTS:1839

RH69724 (e-PCR)
- UniSTS:42565

G32750 (e-PCR)
- UniSTS:117331

PLG_3841 (e-PCR)
- UniSTS:462421

PLGL_8545 (e-PCR)
- UniSTS:467836

A007H01 (e-PCR)
- UniSTS:81025

SHGC-33362 (e-PCR)
- UniSTS:59028

RH122260 (e-PCR)
- UniSTS:134808

SHGC-33485 (e-PCR)
- UniSTS:82589

PLG (e-PCR)
- UniSTS:479908

Gene Ontology Provided by RefSeq

Function	Evidence Code	Pubs
enables serine-type endopeptidase activity	IEA Inferred from Electronic Annotation more info	PubMed
enables signaling receptor binding	IEA Inferred from Electronic Annotation more info	PubMed

Process	Evidence Code	Pubs
involved_in proteolysis	IEA Inferred from Electronic Annotation more info	PubMed

Component	Evidence Code	Pubs
located_in extracellular space	IEA Inferred from Electronic Annotation more info	PubMed
located_in extrinsic component of plasma membrane	IEA Inferred from Electronic Annotation more info	PubMed

General protein information

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Preferred Names: plasminogen

NP_001036540.1

EC 3.4.21.7

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

NM_001043075.1 → NP_001036540.1 plasminogen precursor

See identical proteins and their annotated locations for NP_001036540.1

Status: PROVISIONAL

Source sequence(s)

J04697

UniProtKB/Swiss-Prot

P12545

UniProtKB/TrEMBL

A0A5F7ZJ53

Related

ENSMMUP00000063092.1, ENSMMUT00000086514.1

Conserved Domains (5) summary

smart00020
Location:580 → 803

Tryp_SPc; Trypsin-like serine protease

smart00130
Location:184 → 263

KR; Kringle domain

cd00108
Location:102 → 182

KR; Kringle domain; Kringle domains are believed to play a role in binding mediators, such as peptides, other proteins, membranes, or phospholipids. They are autonomous structural domains, found in a varying number of copies, in blood clotting and ...

cd00190
Location:581 → 804

Tryp_SPc; Trypsin-like serine protease; Many of these are synthesized as inactive precursor zymogens that are cleaved during limited proteolysis to generate their active forms. Alignment contains also inactive enzymes that have substitutions of the catalytic triad ...

cd01099
Location:59 → 97

PAN_AP_HGF; Subfamily of PAN/APPLE-like domains; present in N-terminal (N) domains of plasminogen/hepatocyte growth factor proteins, and various proteins found in Bilateria, such as leech anti-platelet proteins. PAN/APPLE domains fulfill diverse biological functions ...