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    ALAS2 5'-aminolevulinate synthase 2 [ Macaca mulatta (Rhesus monkey) ]

    Gene ID: 704727, updated on 17-Aug-2024

    Summary

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    Official Symbol
    ALAS2provided by VGNC
    Official Full Name
    5'-aminolevulinate synthase 2provided by VGNC
    Primary source
    VGNC:VGNC:69781
    Locus tag
    EGK_20542
    See related
    Ensembl:ENSMMUG00000008429
    Gene type
    protein coding
    RefSeq status
    MODEL
    Organism
    Macaca mulatta
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Cercopithecidae; Cercopithecinae; Macaca
    Orthologs
    human mouse all
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    Genomic context

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    See ALAS2 in Genome Data Viewer
    Location:
    chromosome: X
    Exon count:
    10
    Annotation release Status Assembly Chr Location
    103 current Mmul_10 (GCF_003339765.1) X NC_041774.1 (54735685..54755120, complement)
    102 previous assembly Mmul_8.0.1 (GCF_000772875.2) X NC_027913.1 (54427328..54450004, complement)

    Chromosome X - NC_041774.1Genomic Context describing neighboring genes Neighboring gene 6-phosphofructo-2-kinase/fructose-2,6-biphosphatase 1 Neighboring gene apurinic/apyrimidinic endodeoxyribonuclease 2 Neighboring gene replication protein A 70 kDa DNA-binding subunit pseudogene Neighboring gene PAGE family member 2B Neighboring gene putative G antigen family E member 3

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. Genome sequencing and comparison of two nonhuman primate animal models, the cynomolgus and Chinese rhesus macaques. Yan G, et al. Nat Biotechnol, 2011 Oct 16. PMID 22002653
    2. A new rhesus macaque assembly and annotation for next-generation sequencing analyses. Zimin AV, et al. Biol Direct, 2014 Oct 14. PMID 25319552, Free PMC Article
    3. Manual GO annotation of predictive protein signatures: the InterPro approach to GO curation. Burge S, et al. Database (Oxford), 2012. PMID 22301074, Free PMC Article
    4. TreeGrafter: phylogenetic tree-based annotation of proteins with Gene Ontology terms and other annotations. Tang H, et al. Bioinformatics, 2019 Feb 1. PMID 30032202, Free PMC Article

    GeneRIFs: Gene References Into Functions

    General gene information

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    Markers

    Homology

    Gene Ontology Provided by RefSeq

    Function Evidence Code Pubs
    enables 5-aminolevulinate synthase activity IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    enables pyridoxal phosphate binding IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    Process Evidence Code Pubs
    involved_in erythrocyte development IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    involved_in heme biosynthetic process IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    involved_in hemoglobin biosynthetic process IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    Component Evidence Code Pubs
    located_in mitochondrial matrix IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    located_in mitochondrion IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 

    General protein information

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    Preferred Names
    5-aminolevulinate synthase, erythroid-specific, mitochondrial; LOW QUALITY PROTEIN: 5-aminolevulinate synthase, erythroid-specific, mitochondrial
    Names
    aminolevulinate, delta-, synthase 2
    XP_028698383.1

    NCBI Reference Sequences (RefSeq)

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    RefSeqs of Annotated Genomes: Macaca mulatta Annotation Release 103 details...Open this link in a new tab

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference Mmul_10 Primary Assembly

    Genomic

    1. NC_041774.1 Reference Mmul_10 Primary Assembly

      Range
      54735685..54755120 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_028842550.1 → XP_028698383.1  LOW QUALITY PROTEIN: 5-aminolevulinate synthase, erythroid-specific, mitochondrial

      UniProtKB/TrEMBL
      A0A5F8A044
      Related
      ENSMMUP00000011054.4, ENSMMUT00000011787.4
      Conserved Domains (2) summary
      TIGR01821
      Location:130 → 535
      5aminolev_synth; 5-aminolevulinic acid synthase
      pfam09029
      Location:29 → 124
      Preseq_ALAS; 5-aminolevulinate synthase presequence
    Nucleotide Protein
    Heading Accession and Version

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