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    STUB1 STIP1 homology and U-box containing protein 1 [ Macaca mulatta (Rhesus monkey) ]

    Gene ID: 697105, updated on 17-Aug-2024

    Summary

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    Official Symbol
    STUB1provided by VGNC
    Official Full Name
    STIP1 homology and U-box containing protein 1provided by VGNC
    Primary source
    VGNC:VGNC:99598
    Gene type
    protein coding
    RefSeq status
    PROVISIONAL
    Organism
    Macaca mulatta
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Cercopithecidae; Cercopithecinae; Macaca
    Orthologs
    human mouse all
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    Genomic context

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    See STUB1 in Genome Data Viewer
    Location:
    chromosome: 20
    Exon count:
    14
    Annotation release Status Assembly Chr Location
    103 current Mmul_10 (GCF_003339765.1) 20 NC_041773.1 (709197..713265)
    102 previous assembly Mmul_8.0.1 (GCF_000772875.2) 20 NC_027912.1 (667409..671070)

    Chromosome 20 - NC_041773.1Genomic Context describing neighboring genes Neighboring gene ras homolog family member T2 Neighboring gene uncharacterized LOC106994901 Neighboring gene rhomboid like 1 Neighboring gene jumonji domain containing 8 Neighboring gene WD repeat domain 24 Neighboring gene uncharacterized LOC114674436 Neighboring gene F-box and leucine rich repeat protein 16

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. A new rhesus macaque assembly and annotation for next-generation sequencing analyses. Zimin AV, et al. Biol Direct, 2014 Oct 14. PMID 25319552, Free PMC Article
    2. TreeGrafter: phylogenetic tree-based annotation of proteins with Gene Ontology terms and other annotations. Tang H, et al. Bioinformatics, 2019 Feb 1. PMID 30032202, Free PMC Article

    GeneRIFs: Gene References Into Functions

    General gene information

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    Markers

    Homology

    Gene Ontology Provided by RefSeq

    Function Evidence Code Pubs
    enables protein-folding chaperone binding IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    enables ubiquitin protein ligase activity IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    Process Evidence Code Pubs
    involved_in cellular response to misfolded protein IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    involved_in positive regulation of proteolysis IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    involved_in proteasome-mediated ubiquitin-dependent protein catabolic process IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    involved_in protein polyubiquitination IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    involved_in protein quality control for misfolded or incompletely synthesized proteins IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    Component Evidence Code Pubs
    located_in Z disc IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    located_in cytoplasm IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 

    General protein information

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    Preferred Names
    E3 ubiquitin-protein ligase CHIP
    NP_001244487.1
    XP_028696231.1
    XP_028696232.1

    NCBI Reference Sequences (RefSeq)

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    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_001257558.1 → NP_001244487.1  E3 ubiquitin-protein ligase CHIP

      See identical proteins and their annotated locations for NP_001244487.1

      Status: PROVISIONAL

      Source sequence(s)
      JU332467
      UniProtKB/TrEMBL
      H9FNL3
      Conserved Domains (4) summary
      PLN03088
      Location:26 → 126
      PLN03088; SGT1, suppressor of G2 allele of SKP1; Provisional
      sd00006
      Location:26 → 54
      TPR; TPR repeat [structural motif]
      cd16654
      Location:227 → 293
      RING-Ubox_CHIP; U-box domain, a modified RING finger, found in carboxyl terminus of HSP70-interacting protein (CHIP) and similar proteins
      pfam18391
      Location:142 → 225
      CHIP_TPR_N; CHIP N-terminal tetratricopeptide repeat domain

    RefSeqs of Annotated Genomes: Macaca mulatta Annotation Release 103 details...Open this link in a new tab

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference Mmul_10 Primary Assembly

    Genomic

    1. NC_041773.1 Reference Mmul_10 Primary Assembly

      Range
      709197..713265
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_028840398.1 → XP_028696231.1  E3 ubiquitin-protein ligase CHIP isoform X1

      Conserved Domains (4) summary
      sd00006
      Location:26 → 53
      TPR; TPR repeat [structural motif]
      cd16654
      Location:208 → 274
      RING-Ubox_CHIP; U-box domain, a modified RING finger, found in carboxyl terminus of HSP70-interacting protein (CHIP) and similar proteins
      pfam12895
      Location:54 → 101
      ANAPC3; Anaphase-promoting complex, cyclosome, subunit 3
      pfam18391
      Location:123 → 206
      CHIP_TPR_N; CHIP N-terminal tetratricopeptide repeat domain

    2. XM_028840399.1 → XP_028696232.1  E3 ubiquitin-protein ligase CHIP isoform X2

      UniProtKB/TrEMBL
      G7NQE5
      Conserved Domains (3) summary
      sd00006
      Location:21 → 51
      TPR; TPR repeat [structural motif]
      cd16654
      Location:155 → 221
      RING-Ubox_CHIP; U-box domain, a modified RING finger, found in carboxyl terminus of HSP70-interacting protein (CHIP) and similar proteins
      pfam12895
      Location:1 → 48
      ANAPC3; Anaphase-promoting complex, cyclosome, subunit 3
    Nucleotide Protein
    Heading Accession and Version

    Gene LinkOut

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