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    ERAP1 endoplasmic reticulum aminopeptidase 1 [ Macaca mulatta (Rhesus monkey) ]

    Gene ID: 699996, updated on 17-Aug-2024

    Summary

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    Official Symbol
    ERAP1provided by VGNC
    Official Full Name
    endoplasmic reticulum aminopeptidase 1provided by VGNC
    Primary source
    VGNC:VGNC:72066
    See related
    Ensembl:ENSMMUG00000002063
    Gene type
    protein coding
    RefSeq status
    MODEL
    Organism
    Macaca mulatta
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Cercopithecidae; Cercopithecinae; Macaca
    Also known as
    ARTS-1
    Orthologs
    human mouse all
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    Genomic context

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    See ERAP1 in Genome Data Viewer
    Location:
    chromosome: 6
    Exon count:
    20
    Annotation release Status Assembly Chr Location
    103 current Mmul_10 (GCF_003339765.1) 6 NC_041759.1 (93592808..93640640, complement)
    102 previous assembly Mmul_8.0.1 (GCF_000772875.2) 6 NC_027898.1 (93740336..93774670, complement)

    Chromosome 6 - NC_041759.1Genomic Context describing neighboring genes Neighboring gene uncharacterized LOC106998863 Neighboring gene calpastatin Neighboring gene uncharacterized LOC114678861 Neighboring gene uncharacterized LOC106998865 Neighboring gene uncharacterized LOC114678862 Neighboring gene uncharacterized LOC114678864 Neighboring gene endoplasmic reticulum aminopeptidase 2

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. A new rhesus macaque assembly and annotation for next-generation sequencing analyses. Zimin AV, et al. Biol Direct, 2014 Oct 14. PMID 25319552, Free PMC Article
    2. Manual GO annotation of predictive protein signatures: the InterPro approach to GO curation. Burge S, et al. Database (Oxford), 2012. PMID 22301074, Free PMC Article
    3. TreeGrafter: phylogenetic tree-based annotation of proteins with Gene Ontology terms and other annotations. Tang H, et al. Bioinformatics, 2019 Feb 1. PMID 30032202, Free PMC Article

    GeneRIFs: Gene References Into Functions

    General gene information

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    Markers

    Homology

    Gene Ontology Provided by RefSeq

    Function Evidence Code Pubs
    enables metalloaminopeptidase activity IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    enables peptide binding IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    enables zinc ion binding IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    Process Evidence Code Pubs
    involved_in peptide catabolic process IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    involved_in proteolysis IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    Component Evidence Code Pubs
    located_in cytoplasm IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 

    General protein information

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    Preferred Names
    endoplasmic reticulum aminopeptidase 1
    Names
    type 1 tumor necrosis factor receptor shedding aminopeptidase regulator

    NCBI Reference Sequences (RefSeq)

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    RefSeqs of Annotated Genomes: Macaca mulatta Annotation Release 103 details...Open this link in a new tab

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference Mmul_10 Primary Assembly

    Genomic

    1. NC_041759.1 Reference Mmul_10 Primary Assembly

      Range
      93592808..93640640 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_028849585.1 → XP_028705418.1  endoplasmic reticulum aminopeptidase 1 isoform X2

      UniProtKB/TrEMBL
      A0A1D5Q5Y4, A0A1D5QC90
      Related
      ENSMMUP00000045659.2, ENSMMUT00000064868.2
      Conserved Domains (2) summary
      pfam11838
      Location:597 → 891
      ERAP1_C; ERAP1-like C-terminal domain
      cd09601
      Location:61 → 526
      M1_APN-Q_like; Peptidase M1 aminopeptidase N catalytic domain family which includes aminopeptidase N (APN), aminopeptidase Q (APQ), tricorn interacting factor F3, and endoplasmic reticulum aminopeptidase 1 (ERAP1)

    2. XM_001094790.4 → XP_001094790.3  endoplasmic reticulum aminopeptidase 1 isoform X1

      UniProtKB/TrEMBL
      A0A1D5Q8U0, G7MVG9
      Related
      ENSMMUP00000044458.2, ENSMMUT00000058059.2
      Conserved Domains (2) summary
      pfam11838
      Location:597 → 916
      ERAP1_C; ERAP1-like C-terminal domain
      cd09601
      Location:61 → 526
      M1_APN-Q_like; Peptidase M1 aminopeptidase N catalytic domain family which includes aminopeptidase N (APN), aminopeptidase Q (APQ), tricorn interacting factor F3, and endoplasmic reticulum aminopeptidase 1 (ERAP1)

    3. XM_028849584.1 → XP_028705417.1  endoplasmic reticulum aminopeptidase 1 isoform X1

      UniProtKB/TrEMBL
      A0A1D5Q8U0, G7MVG9
      Related
      ENSMMUP00000075891.1, ENSMMUT00000088960.1
      Conserved Domains (2) summary
      pfam11838
      Location:597 → 916
      ERAP1_C; ERAP1-like C-terminal domain
      cd09601
      Location:61 → 526
      M1_APN-Q_like; Peptidase M1 aminopeptidase N catalytic domain family which includes aminopeptidase N (APN), aminopeptidase Q (APQ), tricorn interacting factor F3, and endoplasmic reticulum aminopeptidase 1 (ERAP1)
    Nucleotide Protein
    Heading Accession and Version

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