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    MLKL mixed lineage kinase domain like pseudokinase [ Macaca mulatta (Rhesus monkey) ]

    Gene ID: 710316, updated on 17-Aug-2024

    Summary

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    Official Symbol
    MLKLprovided by VGNC
    Official Full Name
    mixed lineage kinase domain like pseudokinaseprovided by VGNC
    Primary source
    VGNC:VGNC:82188
    Locus tag
    EGK_12996
    See related
    Ensembl:ENSMMUG00000008378
    Gene type
    protein coding
    RefSeq status
    MODEL
    Organism
    Macaca mulatta
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Cercopithecidae; Cercopithecinae; Macaca
    Orthologs
    human mouse all
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    Genomic context

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    See MLKL in Genome Data Viewer
    Location:
    chromosome: 20
    Exon count:
    13
    Annotation release Status Assembly Chr Location
    103 current Mmul_10 (GCF_003339765.1) 20 NC_041773.1 (61635338..61664485, complement)
    102 previous assembly Mmul_8.0.1 (GCF_000772875.2) 20 NC_027912.1 (58939037..58968616, complement)

    Chromosome 20 - NC_041773.1Genomic Context describing neighboring genes Neighboring gene 10 kDa heat shock protein, mitochondrial pseudogene Neighboring gene ring finger and WD repeat domain 3 Neighboring gene lamina-associated polypeptide 2 Neighboring gene fatty acid 2-hydroxylase Neighboring gene uncharacterized LOC114674277

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. Genome sequencing and comparison of two nonhuman primate animal models, the cynomolgus and Chinese rhesus macaques. Yan G, et al. Nat Biotechnol, 2011 Oct 16. PMID 22002653
    2. A new rhesus macaque assembly and annotation for next-generation sequencing analyses. Zimin AV, et al. Biol Direct, 2014 Oct 14. PMID 25319552, Free PMC Article
    3. Manual GO annotation of predictive protein signatures: the InterPro approach to GO curation. Burge S, et al. Database (Oxford), 2012. PMID 22301074, Free PMC Article
    4. TreeGrafter: phylogenetic tree-based annotation of proteins with Gene Ontology terms and other annotations. Tang H, et al. Bioinformatics, 2019 Feb 1. PMID 30032202, Free PMC Article

    GeneRIFs: Gene References Into Functions

    General gene information

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    Markers

    Homology

    Gene Ontology Provided by RefSeq

    Function Evidence Code Pubs
    enables ATP binding IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    enables protein kinase activity IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    Process Evidence Code Pubs
    involved_in cell surface receptor signaling pathway IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    involved_in protein phosphorylation IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    Component Evidence Code Pubs
    located_in plasma membrane IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 

    General protein information

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    Preferred Names
    mixed lineage kinase domain-like protein
    Names
    Mixed lineage kinase domain-like protein

    NCBI Reference Sequences (RefSeq)

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    RefSeqs of Annotated Genomes: Macaca mulatta Annotation Release 103 details...Open this link in a new tab

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference Mmul_10 Primary Assembly

    Genomic

    1. NC_041773.1 Reference Mmul_10 Primary Assembly

      Range
      61635338..61664485 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_015126620.2 → XP_014982106.1  mixed lineage kinase domain-like protein isoform X1

      Conserved Domains (2) summary
      cd21037
      Location:5 → 121
      MLKL_NTD; N-terminal domain of mixed lineage kinase domain-like protein (MLKL) and similar proteins
      cl21453
      Location:192 → 472
      PKc_like; Protein Kinases, catalytic domain

    2. XM_015126621.2 → XP_014982107.1  mixed lineage kinase domain-like protein isoform X1

      Conserved Domains (2) summary
      cd21037
      Location:5 → 121
      MLKL_NTD; N-terminal domain of mixed lineage kinase domain-like protein (MLKL) and similar proteins
      cl21453
      Location:192 → 472
      PKc_like; Protein Kinases, catalytic domain

    3. XM_015126623.2 → XP_014982109.1  mixed lineage kinase domain-like protein isoform X2

      UniProtKB/TrEMBL
      A0A5S6RCK7, A0A8J8YIM7, F7HMN7, G7NR15
      Related
      ENSMMUP00000010982.4, ENSMMUT00000011711.4
      Conserved Domains (2) summary
      cd21037
      Location:5 → 121
      MLKL_NTD; N-terminal domain of mixed lineage kinase domain-like protein (MLKL) and similar proteins
      cl21453
      Location:192 → 469
      PKc_like; Protein Kinases, catalytic domain

    4. XM_028840659.1 → XP_028696492.1  mixed lineage kinase domain-like protein isoform X1

      Conserved Domains (2) summary
      cd21037
      Location:5 → 121
      MLKL_NTD; N-terminal domain of mixed lineage kinase domain-like protein (MLKL) and similar proteins
      cl21453
      Location:192 → 472
      PKc_like; Protein Kinases, catalytic domain

    5. XM_015126622.2 → XP_014982108.1  mixed lineage kinase domain-like protein isoform X1

      Conserved Domains (2) summary
      cd21037
      Location:5 → 121
      MLKL_NTD; N-terminal domain of mixed lineage kinase domain-like protein (MLKL) and similar proteins
      cl21453
      Location:192 → 472
      PKc_like; Protein Kinases, catalytic domain

    6. XM_015126624.2 → XP_014982110.1  mixed lineage kinase domain-like protein isoform X3

      Conserved Domains (2) summary
      cd21037
      Location:5 → 121
      MLKL_NTD; N-terminal domain of mixed lineage kinase domain-like protein (MLKL) and similar proteins
      cl21453
      Location:192 → 397
      PKc_like; Protein Kinases, catalytic domain
    Nucleotide Protein
    Heading Accession and Version

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