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    MERTK MER proto-oncogene, tyrosine kinase [ Macaca mulatta (Rhesus monkey) ]

    Gene ID: 698330, updated on 17-Aug-2024

    Summary

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    Official Symbol
    MERTKprovided by VGNC
    Official Full Name
    MER proto-oncogene, tyrosine kinaseprovided by VGNC
    Primary source
    VGNC:VGNC:74706
    See related
    Ensembl:ENSMMUG00000010066
    Gene type
    protein coding
    RefSeq status
    MODEL
    Organism
    Macaca mulatta
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Cercopithecidae; Cercopithecinae; Macaca
    Orthologs
    human mouse all
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    Genomic context

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    See MERTK in Genome Data Viewer
    Location:
    chromosome: 13
    Exon count:
    19
    Annotation release Status Assembly Chr Location
    103 current Mmul_10 (GCF_003339765.1) 13 NC_041766.1 (15115927..15252511)
    102 previous assembly Mmul_8.0.1 (GCF_000772875.2) 13 NC_027905.1 (106939483..107074688)

    Chromosome 13 - NC_041766.1Genomic Context describing neighboring genes Neighboring gene uncharacterized LOC106993131 Neighboring gene eukaryotic translation elongation factor 1 epsilon-1-like Neighboring gene 40S ribosomal protein S20 pseudogene Neighboring gene RNA transcription, translation and transport factor protein pseudogene Neighboring gene transmembrane protein 87B Neighboring gene fibulin 7

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. A new rhesus macaque assembly and annotation for next-generation sequencing analyses. Zimin AV, et al. Biol Direct, 2014 Oct 14. PMID 25319552, Free PMC Article
    2. Manual GO annotation of predictive protein signatures: the InterPro approach to GO curation. Burge S, et al. Database (Oxford), 2012. PMID 22301074, Free PMC Article
    3. TreeGrafter: phylogenetic tree-based annotation of proteins with Gene Ontology terms and other annotations. Tang H, et al. Bioinformatics, 2019 Feb 1. PMID 30032202, Free PMC Article

    GeneRIFs: Gene References Into Functions

    General gene information

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    Markers

    Homology

    Gene Ontology Provided by RefSeq

    Function Evidence Code Pubs
    enables ATP binding IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    enables protein binding IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    enables transmembrane receptor protein tyrosine kinase activity IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    Process Evidence Code Pubs
    involved_in cell migration IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    involved_in cell surface receptor protein tyrosine kinase signaling pathway IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    involved_in multicellular organism development IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    involved_in nervous system development IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    involved_in phagocytosis IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    involved_in positive regulation of kinase activity IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    involved_in protein phosphorylation IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    Component Evidence Code Pubs
    part_of receptor complex IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 

    General protein information

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    Preferred Names
    tyrosine-protein kinase Mer
    Names
    c-mer proto-oncogene tyrosine kinase
    XP_001086951.2

    NCBI Reference Sequences (RefSeq)

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    RefSeqs of Annotated Genomes: Macaca mulatta Annotation Release 103 details...Open this link in a new tab

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference Mmul_10 Primary Assembly

    Genomic

    1. NC_041766.1 Reference Mmul_10 Primary Assembly

      Range
      15115927..15252511
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_001086951.4 → XP_001086951.2  tyrosine-protein kinase Mer

      UniProtKB/TrEMBL
      F6T7N0, G7NAX0
      Related
      ENSMMUP00000013160.4, ENSMMUT00000014052.4
      Conserved Domains (4) summary
      cd05749
      Location:432 → 512
      Ig2_Axl_Tyro3_like; Second immunoglobulin (Ig)-like domain of Axl/Tyro3 family receptor tyrosine kinases (RTKs)
      cd00063
      Location:517 → 611
      FN3; Fibronectin type 3 domain; One of three types of internal repeats found in the plasma protein fibronectin. Its tenth fibronectin type III repeat contains an RGD cell recognition sequence in a flexible loop between 2 strands. Approximately 2% of all ...
      cd14204
      Location:812 → 1095
      PTKc_Mer; Catalytic Domain of the Protein Tyrosine Kinase, Mer
      cd00096
      Location:344 → 409
      Ig; Immunoglobulin domain
    Nucleotide Protein
    Heading Accession and Version

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