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    ADAMTS5 ADAM metallopeptidase with thrombospondin type 1 motif 5 [ Macaca mulatta (Rhesus monkey) ]

    Gene ID: 707672, updated on 17-Aug-2024

    Summary

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    Official Symbol
    ADAMTS5provided by VGNC
    Official Full Name
    ADAM metallopeptidase with thrombospondin type 1 motif 5provided by VGNC
    Primary source
    VGNC:VGNC:69499
    See related
    Ensembl:ENSMMUG00000013405
    Gene type
    protein coding
    RefSeq status
    MODEL
    Organism
    Macaca mulatta
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Cercopithecidae; Cercopithecinae; Macaca
    Orthologs
    human mouse all
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    Genomic context

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    See ADAMTS5 in Genome Data Viewer
    Location:
    chromosome: 3
    Exon count:
    9
    Annotation release Status Assembly Chr Location
    103 current Mmul_10 (GCF_003339765.1) 3 NC_041756.1 (19704689..19750074)
    102 previous assembly Mmul_8.0.1 (GCF_000772875.2) 3 NC_027895.1 (19965199..20010068)

    Chromosome 3 - NC_041756.1Genomic Context describing neighboring genes Neighboring gene eukaryotic initiation factor 4A-I-like Neighboring gene uncharacterized LOC106997280 Neighboring gene ADAM metallopeptidase with thrombospondin type 1 motif 1 Neighboring gene uncharacterized LOC114676830 Neighboring gene cysteine and tyrosine rich 1

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. Manual GO annotation of predictive protein signatures: the InterPro approach to GO curation. Burge S, et al. Database (Oxford), 2012. PMID 22301074, Free PMC Article
    2. TreeGrafter: phylogenetic tree-based annotation of proteins with Gene Ontology terms and other annotations. Tang H, et al. Bioinformatics, 2019 Feb 1. PMID 30032202, Free PMC Article

    GeneRIFs: Gene References Into Functions

    General gene information

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    Markers

    Homology

    Gene Ontology Provided by RefSeq

    Function Evidence Code Pubs
    enables metalloendopeptidase activity IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    enables zinc ion binding IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    Process Evidence Code Pubs
    involved_in extracellular matrix organization IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    involved_in proteolysis IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    Component Evidence Code Pubs
    located_in collagen-containing extracellular matrix IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 

    General protein information

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    Preferred Names
    A disintegrin and metalloproteinase with thrombospondin motifs 5

    NCBI Reference Sequences (RefSeq)

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    RefSeqs of Annotated Genomes: Macaca mulatta Annotation Release 103 details...Open this link in a new tab

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference Mmul_10 Primary Assembly

    Genomic

    1. NC_041756.1 Reference Mmul_10 Primary Assembly

      Range
      19704689..19750074
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_028845389.1 → XP_028701222.1  A disintegrin and metalloproteinase with thrombospondin motifs 5

      UniProtKB/TrEMBL
      F6Z3S6, G7MNA8
      Related
      ENSMMUP00000017606.4, ENSMMUT00000018801.4
      Conserved Domains (4) summary
      smart00209
      Location:570 → 622
      TSP1; Thrombospondin type 1 repeats
      cd04273
      Location:269 → 473
      ZnMc_ADAMTS_like; Zinc-dependent metalloprotease, ADAMTS_like subgroup. ADAMs (A Disintegrin And Metalloprotease) are glycoproteins, which play roles in cell signaling, cell fusion, and cell-cell interactions. This particular subfamily represents domain architectures that ...
      pfam05986
      Location:732 → 852
      ADAM_spacer1; ADAM-TS Spacer 1
      pfam01562
      Location:66 → 168
      Pep_M12B_propep; Reprolysin family propeptide

    2. XM_028845390.1 → XP_028701223.1  A disintegrin and metalloproteinase with thrombospondin motifs 5

      UniProtKB/TrEMBL
      F6Z3S6, G7MNA8
      Conserved Domains (4) summary
      smart00209
      Location:570 → 622
      TSP1; Thrombospondin type 1 repeats
      cd04273
      Location:269 → 473
      ZnMc_ADAMTS_like; Zinc-dependent metalloprotease, ADAMTS_like subgroup. ADAMs (A Disintegrin And Metalloprotease) are glycoproteins, which play roles in cell signaling, cell fusion, and cell-cell interactions. This particular subfamily represents domain architectures that ...
      pfam05986
      Location:732 → 852
      ADAM_spacer1; ADAM-TS Spacer 1
      pfam01562
      Location:66 → 168
      Pep_M12B_propep; Reprolysin family propeptide
    Nucleotide Protein
    Heading Accession and Version

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