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    PCLO piccolo presynaptic cytomatrix protein [ Macaca mulatta (Rhesus monkey) ]

    Gene ID: 708685, updated on 17-Aug-2024

    Summary

    Official Symbol
    PCLOprovided by VGNC
    Official Full Name
    piccolo presynaptic cytomatrix proteinprovided by VGNC
    Primary source
    VGNC:VGNC:75595
    See related
    Ensembl:ENSMMUG00000021678
    Gene type
    protein coding
    RefSeq status
    MODEL
    Organism
    Macaca mulatta
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Cercopithecidae; Cercopithecinae; Macaca
    Orthologs
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    Try the new Transcript table

    Genomic context

    See PCLO in Genome Data Viewer
    Location:
    chromosome: 3
    Exon count:
    28
    Annotation release Status Assembly Chr Location
    103 current Mmul_10 (GCF_003339765.1) 3 NC_041756.1 (122985344..123389764)
    102 previous assembly Mmul_8.0.1 (GCF_000772875.2) 3 NC_027895.1 (111024019..111428642)

    Chromosome 3 - NC_041756.1Genomic Context describing neighboring genes Neighboring gene UV excision repair protein RAD23 homolog B pseudogene Neighboring gene semaphorin 3E Neighboring gene uncharacterized LOC114676995 Neighboring gene bifunctional methylenetetrahydrofolate dehydrogenase/cyclohydrolase, mitochondrial pseudogene Neighboring gene acyl-CoA desaturase pseudogene

    Genomic regions, transcripts, and products

    General gene information

    Markers

    Gene Ontology Provided by RefSeq

    Function Evidence Code Pubs
    enables metal ion binding IEA
    Inferred from Electronic Annotation
    more info
    PubMed 
    enables protein binding IEA
    Inferred from Electronic Annotation
    more info
    PubMed 
    enables structural constituent of presynaptic active zone IEA
    Inferred from Electronic Annotation
    more info
    PubMed 
    Process Evidence Code Pubs
    involved_in presynaptic active zone assembly IEA
    Inferred from Electronic Annotation
    more info
    PubMed 
    involved_in protein localization to synapse IEA
    Inferred from Electronic Annotation
    more info
    PubMed 
    Component Evidence Code Pubs
    located_in GABA-ergic synapse IEA
    Inferred from Electronic Annotation
    more info
    PubMed 
    located_in axon IEA
    Inferred from Electronic Annotation
    more info
    PubMed 
    located_in cytoskeleton of presynaptic active zone IEA
    Inferred from Electronic Annotation
    more info
    PubMed 
    located_in glutamatergic synapse IEA
    Inferred from Electronic Annotation
    more info
    PubMed 

    General protein information

    Preferred Names
    protein piccolo
    Names
    protein piccolo-like

    NCBI Reference Sequences (RefSeq)

    NEW Try the new Transcript table

    RefSeqs of Annotated Genomes: Macaca mulatta Annotation Release 103 details...Open this link in a new tab

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference Mmul_10 Primary Assembly

    Genomic

    1. NC_041756.1 Reference Mmul_10 Primary Assembly

      Range
      122985344..123389764
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_028846129.1XP_028701962.1  protein piccolo isoform X1

      UniProtKB/TrEMBL
      A0A5F7Z7X4
      Conserved Domains (10) summary
      PTZ00121
      Location:11331639
      PTZ00121; MAEBL; Provisional
      cd04031
      Location:46994831
      C2A_RIM1alpha; C2 domain first repeat contained in Rab3-interacting molecule (RIM) proteins
      PHA03247
      Location:245867
      PHA03247; large tegument protein UL36; Provisional
      PRK07764
      Location:32413
      PRK07764; DNA polymerase III subunits gamma and tau; Validated
      PRK10263
      Location:34383943
      PRK10263; DNA translocase FtsK; Provisional
      PRK12270
      Location:9251005
      kgd; alpha-ketoglutarate decarboxylase; Reviewed
      cd00992
      Location:45154592
      PDZ_signaling; PDZ domain found in a variety of Eumetazoan signaling molecules, often in tandem arrangements. May be responsible for specific protein-protein interactions, as most PDZ domains bind C-terminal polypeptides, and binding to internal (non-C-terminal) ...
      cd15774
      Location:567628
      FYVE1_PCLO; FYVE-related domain 1 found in protein piccolo
      pfam05715
      Location:10351093
      zf-piccolo; Piccolo Zn-finger
      cl14603
      Location:50715200
      C2; C2 domain
    2. XM_015134172.2XP_014989658.2  protein piccolo isoform X2

      UniProtKB/TrEMBL
      A0A5F7Z7X4, F7HKA9
      Related
      ENSMMUP00000022989.4, ENSMMUT00000024560.4
      Conserved Domains (10) summary
      PTZ00121
      Location:11331639
      PTZ00121; MAEBL; Provisional
      cd04031
      Location:46724804
      C2A_RIM1alpha; C2 domain first repeat contained in Rab3-interacting molecule (RIM) proteins
      PHA03247
      Location:245867
      PHA03247; large tegument protein UL36; Provisional
      PRK07764
      Location:32413
      PRK07764; DNA polymerase III subunits gamma and tau; Validated
      PRK10263
      Location:34383943
      PRK10263; DNA translocase FtsK; Provisional
      PRK12270
      Location:9251005
      kgd; alpha-ketoglutarate decarboxylase; Reviewed
      cd00992
      Location:44744565
      PDZ_signaling; PDZ domain found in a variety of Eumetazoan signaling molecules, often in tandem arrangements. May be responsible for specific protein-protein interactions, as most PDZ domains bind C-terminal polypeptides, and binding to internal (non-C-terminal) ...
      cd15774
      Location:567628
      FYVE1_PCLO; FYVE-related domain 1 found in protein piccolo
      pfam05715
      Location:10351093
      zf-piccolo; Piccolo Zn-finger
      cl14603
      Location:50445173
      C2; C2 domain
    3. XM_015134174.2XP_014989660.2  protein piccolo isoform X3

      UniProtKB/TrEMBL
      A0A5F7Z7X4, A0A5F7ZRW9
      Related
      ENSMMUP00000068371.1, ENSMMUT00000102696.1
      Conserved Domains (10) summary
      PTZ00121
      Location:11331639
      PTZ00121; MAEBL; Provisional
      cd04031
      Location:46724804
      C2A_RIM1alpha; C2 domain first repeat contained in Rab3-interacting molecule (RIM) proteins
      PHA03247
      Location:245867
      PHA03247; large tegument protein UL36; Provisional
      PRK07764
      Location:32413
      PRK07764; DNA polymerase III subunits gamma and tau; Validated
      PRK10263
      Location:34383943
      PRK10263; DNA translocase FtsK; Provisional
      PRK12270
      Location:9251005
      kgd; alpha-ketoglutarate decarboxylase; Reviewed
      cd00992
      Location:44744565
      PDZ_signaling; PDZ domain found in a variety of Eumetazoan signaling molecules, often in tandem arrangements. May be responsible for specific protein-protein interactions, as most PDZ domains bind C-terminal polypeptides, and binding to internal (non-C-terminal) ...
      cd15774
      Location:567628
      FYVE1_PCLO; FYVE-related domain 1 found in protein piccolo
      pfam05715
      Location:10351093
      zf-piccolo; Piccolo Zn-finger
      cl14603
      Location:49835112
      C2; C2 domain
    4. XM_028846131.1XP_028701964.1  protein piccolo isoform X4

      UniProtKB/TrEMBL
      F7F4I5
      Conserved Domains (8) summary
      PTZ00121
      Location:11331639
      PTZ00121; MAEBL; Provisional
      PHA03247
      Location:245867
      PHA03247; large tegument protein UL36; Provisional
      PRK01741
      Location:38213963
      PRK01741; cell division protein ZipA; Provisional
      PRK07764
      Location:32413
      PRK07764; DNA polymerase III subunits gamma and tau; Validated
      PRK10263
      Location:35483943
      PRK10263; DNA translocase FtsK; Provisional
      PRK12270
      Location:9251005
      kgd; alpha-ketoglutarate decarboxylase; Reviewed
      cd15774
      Location:567628
      FYVE1_PCLO; FYVE-related domain 1 found in protein piccolo
      pfam05715
      Location:10351093
      zf-piccolo; Piccolo Zn-finger