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    RALGPS2 Ral GEF with PH domain and SH3 binding motif 2 [ Macaca mulatta (Rhesus monkey) ]

    Gene ID: 717165, updated on 17-Aug-2024

    Summary

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    Official Symbol
    RALGPS2provided by VGNC
    Official Full Name
    Ral GEF with PH domain and SH3 binding motif 2provided by VGNC
    Primary source
    VGNC:VGNC:76572
    Locus tag
    EGK_02001
    See related
    Ensembl:ENSMMUG00000017551
    Gene type
    protein coding
    RefSeq status
    MODEL
    Organism
    Macaca mulatta
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Cercopithecidae; Cercopithecinae; Macaca
    Orthologs
    human mouse all
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    Genomic context

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    See RALGPS2 in Genome Data Viewer
    Location:
    chromosome: 1
    Exon count:
    20
    Annotation release Status Assembly Chr Location
    103 current Mmul_10 (GCF_003339765.1) 1 NC_041754.1 (35947380..36134034)
    102 previous assembly Mmul_8.0.1 (GCF_000772875.2) 1 NC_027893.1 (188555589..188741456, complement)

    Chromosome 1 - NC_041754.1Genomic Context describing neighboring genes Neighboring gene uncharacterized LOC114679382 Neighboring gene uncharacterized LOC114679383 Neighboring gene translation initiation factor IF-2-like Neighboring gene tyrosine-protein phosphatase non-receptor type 2 pseudogene Neighboring gene angiopoietin like 1 Neighboring gene uncharacterized LOC114679385 Neighboring gene 40S ribosomal protein S26-like Neighboring gene FAM20B glycosaminoglycan xylosylkinase

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. A new rhesus macaque assembly and annotation for next-generation sequencing analyses. Zimin AV, et al. Biol Direct, 2014 Oct 14. PMID 25319552, Free PMC Article
    2. Manual GO annotation of predictive protein signatures: the InterPro approach to GO curation. Burge S, et al. Database (Oxford), 2012. PMID 22301074, Free PMC Article
    3. TreeGrafter: phylogenetic tree-based annotation of proteins with Gene Ontology terms and other annotations. Tang H, et al. Bioinformatics, 2019 Feb 1. PMID 30032202, Free PMC Article

    GeneRIFs: Gene References Into Functions

    General gene information

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    Markers

    Homology

    Gene Ontology Provided by RefSeq

    Function Evidence Code Pubs
    enables guanyl-nucleotide exchange factor activity IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    Process Evidence Code Pubs
    involved_in Ras protein signal transduction IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    involved_in positive regulation of GTPase activity IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    Component Evidence Code Pubs
    located_in plasma membrane IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 

    General protein information

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    Preferred Names
    ras-specific guanine nucleotide-releasing factor RalGPS2

    NCBI Reference Sequences (RefSeq)

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    RefSeqs of Annotated Genomes: Macaca mulatta Annotation Release 103 details...Open this link in a new tab

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference Mmul_10 Primary Assembly

    Genomic

    1. NC_041754.1 Reference Mmul_10 Primary Assembly

      Range
      35947380..36134034
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_015122899.2 → XP_014978385.1  ras-specific guanine nucleotide-releasing factor RalGPS2 isoform X1

      UniProtKB/TrEMBL
      A0A663DBH2, A0A8J8XHT6, F6TH23, F6TH31, G7MFF0
      Related
      ENSMMUP00000023105.4, ENSMMUT00000024686.4
      Conserved Domains (2) summary
      smart00147
      Location:45 → 286
      RasGEF; Guanine nucleotide exchange factor for Ras-like small GTPases
      cd13310
      Location:459 → 574
      PH_RalGPS1_2; Ral GEF with PH domain and SH3 binding motif 1 and 2 Pleckstrin homology (PH) domain

    2. XM_015122913.2 → XP_014978399.1  ras-specific guanine nucleotide-releasing factor RalGPS2 isoform X2

      UniProtKB/TrEMBL
      A0A1D5QD76
      Related
      ENSMMUP00000054657.2, ENSMMUT00000060740.2
      Conserved Domains (2) summary
      smart00147
      Location:45 → 286
      RasGEF; Guanine nucleotide exchange factor for Ras-like small GTPases
      cd13310
      Location:433 → 548
      PH_RalGPS1_2; Ral GEF with PH domain and SH3 binding motif 1 and 2 Pleckstrin homology (PH) domain
    Nucleotide Protein
    Heading Accession and Version

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