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    PMS2 PMS1 homolog 2, mismatch repair system component [ Macaca mulatta (Rhesus monkey) ]

    Gene ID: 717589, updated on 17-Aug-2024

    Summary

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    Official Symbol
    PMS2provided by VGNC
    Official Full Name
    PMS1 homolog 2, mismatch repair system componentprovided by VGNC
    Primary source
    VGNC:VGNC:108428
    See related
    Ensembl:ENSMMUG00000030421
    Gene type
    protein coding
    RefSeq status
    MODEL
    Organism
    Macaca mulatta
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Cercopithecidae; Cercopithecinae; Macaca
    Orthologs
    human all
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    Genomic context

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    See PMS2 in Genome Data Viewer
    Location:
    chromosome: 3
    Exon count:
    17
    Annotation release Status Assembly Chr Location
    103 current Mmul_10 (GCF_003339765.1) 3 NC_041756.1 (39920059..39960477)
    102 previous assembly Mmul_8.0.1 (GCF_000772875.2) 3 NC_027895.1 (40740861..40778064)

    Chromosome 3 - NC_041756.1Genomic Context describing neighboring genes Neighboring gene eukaryotic translation initiation factor 2 alpha kinase 1 Neighboring gene ankyrin repeat domain 61 Neighboring gene small nucleolar RNA SNORA42/SNORA80 family Neighboring gene aminoacyl tRNA synthetase complex interacting multifunctional protein 2 Neighboring gene radial spoke head 10 homolog B Neighboring gene CCZ1 homolog, vacuolar protein trafficking and biogenesis associated

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. A new rhesus macaque assembly and annotation for next-generation sequencing analyses. Zimin AV, et al. Biol Direct, 2014 Oct 14. PMID 25319552, Free PMC Article
    2. Manual GO annotation of predictive protein signatures: the InterPro approach to GO curation. Burge S, et al. Database (Oxford), 2012. PMID 22301074, Free PMC Article
    3. TreeGrafter: phylogenetic tree-based annotation of proteins with Gene Ontology terms and other annotations. Tang H, et al. Bioinformatics, 2019 Feb 1. PMID 30032202, Free PMC Article

    GeneRIFs: Gene References Into Functions

    General gene information

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    Markers

    Homology

    Gene Ontology Provided by RefSeq

    Function Evidence Code Pubs
    enables ATP binding IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    enables ATP hydrolysis activity IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    enables ATP-dependent DNA damage sensor activity IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    enables mismatched DNA binding IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    Process Evidence Code Pubs
    involved_in mismatch repair IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    Component Evidence Code Pubs
    part_of MutLalpha complex IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 

    General protein information

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    Preferred Names
    mismatch repair endonuclease PMS2

    NCBI Reference Sequences (RefSeq)

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    RefSeqs of Annotated Genomes: Macaca mulatta Annotation Release 103 details...Open this link in a new tab

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference Mmul_10 Primary Assembly

    Genomic

    1. NC_041756.1 Reference Mmul_10 Primary Assembly

      Range
      39920059..39960477
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_015133250.2 → XP_014988736.2  mismatch repair endonuclease PMS2 isoform X1

      UniProtKB/TrEMBL
      F7DP36
      Related
      ENSMMUP00000051000.2, ENSMMUT00000061802.2
      Conserved Domains (2) summary
      COG0323
      Location:76 → 917
      MutL; DNA mismatch repair ATPase MutL [Replication, recombination and repair]
      TIGR00585
      Location:74 → 405
      mutl; DNA mismatch repair protein MutL

    2. XM_015133251.2 → XP_014988737.2  mismatch repair endonuclease PMS2 isoform X2

      UniProtKB/TrEMBL
      F7DP36, F7E6J2
      Related
      ENSMMUP00000016299.4, ENSMMUT00000017405.4
      Conserved Domains (2) summary
      COG0323
      Location:76 → 865
      MutL; DNA mismatch repair ATPase MutL [Replication, recombination and repair]
      TIGR00585
      Location:74 → 393
      mutl; DNA mismatch repair protein MutL

    3. XM_028845123.1 → XP_028700956.1  mismatch repair endonuclease PMS2 isoform X3

      UniProtKB/TrEMBL
      F7DP36
      Conserved Domains (2) summary
      smart00853
      Location:739 → 785
      MutL_C; MutL C terminal dimerisation domain
      TIGR00585
      Location:74 → 405
      mutl; DNA mismatch repair protein MutL

    4. XM_028845125.1 → XP_028700958.1  mismatch repair endonuclease PMS2 isoform X4

      Conserved Domains (2) summary
      COG0323
      Location:4 → 673
      MutL; DNA mismatch repair ATPase MutL [Replication, recombination and repair]
      cd03484
      Location:39 → 181
      MutL_Trans_hPMS_2_like; MutL_Trans_hPMS2_like: transducer domain, having a ribosomal S5 domain 2-like fold, found in proteins similar to human PSM2 (hPSM2). hPSM2 belongs to the DNA mismatch repair (MutL/MLH1/PMS2) family. This transducer domain is homologous to the second ...

    5. XM_028845124.1 → XP_028700957.1  mismatch repair endonuclease PMS2 isoform X4

      Conserved Domains (2) summary
      COG0323
      Location:4 → 673
      MutL; DNA mismatch repair ATPase MutL [Replication, recombination and repair]
      cd03484
      Location:39 → 181
      MutL_Trans_hPMS_2_like; MutL_Trans_hPMS2_like: transducer domain, having a ribosomal S5 domain 2-like fold, found in proteins similar to human PSM2 (hPSM2). hPSM2 belongs to the DNA mismatch repair (MutL/MLH1/PMS2) family. This transducer domain is homologous to the second ...

    6. XM_028845126.1 → XP_028700959.1  mismatch repair endonuclease PMS2 isoform X5

      Conserved Domains (2) summary
      COG0323
      Location:4 → 592
      MutL; DNA mismatch repair ATPase MutL [Replication, recombination and repair]
      cd03484
      Location:5 → 100
      MutL_Trans_hPMS_2_like; MutL_Trans_hPMS2_like: transducer domain, having a ribosomal S5 domain 2-like fold, found in proteins similar to human PSM2 (hPSM2). hPSM2 belongs to the DNA mismatch repair (MutL/MLH1/PMS2) family. This transducer domain is homologous to the second ...
    Nucleotide Protein
    Heading Accession and Version

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