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    ADAMTS18 ADAM metallopeptidase with thrombospondin type 1 motif 18 [ Macaca mulatta (Rhesus monkey) ]

    Gene ID: 712710, updated on 17-Aug-2024

    Summary

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    Official Symbol
    ADAMTS18provided by VGNC
    Official Full Name
    ADAM metallopeptidase with thrombospondin type 1 motif 18provided by VGNC
    Primary source
    VGNC:VGNC:69442
    See related
    Ensembl:ENSMMUG00000000824
    Gene type
    protein coding
    RefSeq status
    MODEL
    Organism
    Macaca mulatta
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Cercopithecidae; Cercopithecinae; Macaca
    Orthologs
    human mouse all
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    Genomic context

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    See ADAMTS18 in Genome Data Viewer
    Location:
    chromosome: 20
    Exon count:
    22
    Annotation release Status Assembly Chr Location
    103 current Mmul_10 (GCF_003339765.1) 20 NC_041773.1 (64323403..64475751, complement)
    102 previous assembly Mmul_8.0.1 (GCF_000772875.2) 20 NC_027912.1 (61148966..61300967)

    Chromosome 20 - NC_041773.1Genomic Context describing neighboring genes Neighboring gene uncharacterized LOC114674315 Neighboring gene vomeronasal 2 receptor 211 pseudogene Neighboring gene uncharacterized LOC106995085 Neighboring gene prohibitin-like Neighboring gene nudix hydrolase 7

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. Manual GO annotation of predictive protein signatures: the InterPro approach to GO curation. Burge S, et al. Database (Oxford), 2012. PMID 22301074, Free PMC Article
    2. TreeGrafter: phylogenetic tree-based annotation of proteins with Gene Ontology terms and other annotations. Tang H, et al. Bioinformatics, 2019 Feb 1. PMID 30032202, Free PMC Article

    GeneRIFs: Gene References Into Functions

    General gene information

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    Homology

    Gene Ontology Provided by RefSeq

    Function Evidence Code Pubs
    enables metalloendopeptidase activity IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    Process Evidence Code Pubs
    involved_in extracellular matrix organization IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    involved_in proteolysis IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    Component Evidence Code Pubs
    located_in extracellular matrix IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 

    General protein information

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    Preferred Names
    A disintegrin and metalloproteinase with thrombospondin motifs 18
    Names
    a disintegrin and metalloproteinase with thrombospondin motifs 18-like

    NCBI Reference Sequences (RefSeq)

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    RefSeqs of Annotated Genomes: Macaca mulatta Annotation Release 103 details...Open this link in a new tab

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference Mmul_10 Primary Assembly

    Genomic

    1. NC_041773.1 Reference Mmul_10 Primary Assembly

      Range
      64323403..64475751 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_028840641.1 → XP_028696474.1  A disintegrin and metalloproteinase with thrombospondin motifs 18

      UniProtKB/TrEMBL
      G7NR39
      Related
      ENSMMUP00000067249.1, ENSMMUT00000083553.1
      Conserved Domains (6) summary
      smart00209
      Location:420 → 471
      TSP1; Thrombospondin type 1 repeats
      cd04273
      Location:121 → 322
      ZnMc_ADAMTS_like; Zinc-dependent metalloprotease, ADAMTS_like subgroup. ADAMs (A Disintegrin And Metalloprotease) are glycoproteins, which play roles in cell signaling, cell fusion, and cell-cell interactions. This particular subfamily represents domain architectures that ...
      pfam05986
      Location:577 → 689
      ADAM_spacer1; ADAM-TS Spacer 1
      pfam08686
      Location:1016 → 1046
      PLAC; PLAC (protease and lacunin) domain
      pfam17771
      Location:339 → 406
      ADAM_CR_2; ADAM cysteine-rich domain
      pfam19030
      Location:763 → 819
      TSP1_ADAMTS; Thrombospondin type 1 domain
    Nucleotide Protein
    Heading Accession and Version

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