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    AGAP2 ArfGAP with GTPase domain, ankyrin repeat and PH domain 2 [ Macaca mulatta (Rhesus monkey) ]

    Gene ID: 715504, updated on 17-Aug-2024

    Summary

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    Official Symbol
    AGAP2provided by VGNC
    Official Full Name
    ArfGAP with GTPase domain, ankyrin repeat and PH domain 2provided by VGNC
    Primary source
    VGNC:VGNC:69620
    See related
    Ensembl:ENSMMUG00000023690
    Gene type
    protein coding
    RefSeq status
    PROVISIONAL
    Organism
    Macaca mulatta
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Cercopithecidae; Cercopithecinae; Macaca
    Also known as
    CENTG1
    Orthologs
    human mouse all
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    Genomic context

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    See AGAP2 in Genome Data Viewer
    Location:
    chromosome: 11
    Exon count:
    20
    Annotation release Status Assembly Chr Location
    103 current Mmul_10 (GCF_003339765.1) 11 NC_041764.1 (57309381..57327938, complement)
    102 previous assembly Mmul_8.0.1 (GCF_000772875.2) 11 NC_027903.1 (56531734..56544291, complement)

    Chromosome 11 - NC_041764.1Genomic Context describing neighboring genes Neighboring gene 60S ribosomal protein L13a pseudogene Neighboring gene OS9 endoplasmic reticulum lectin Neighboring gene tetraspanin 31 Neighboring gene vegetative cell wall protein gp1-like Neighboring gene cyclin dependent kinase 4

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. A new rhesus macaque assembly and annotation for next-generation sequencing analyses. Zimin AV, et al. Biol Direct, 2014 Oct 14. PMID 25319552, Free PMC Article
    2. Manual GO annotation of predictive protein signatures: the InterPro approach to GO curation. Burge S, et al. Database (Oxford), 2012. PMID 22301074, Free PMC Article
    3. TreeGrafter: phylogenetic tree-based annotation of proteins with Gene Ontology terms and other annotations. Tang H, et al. Bioinformatics, 2019 Feb 1. PMID 30032202, Free PMC Article

    GeneRIFs: Gene References Into Functions

    General gene information

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    Homology

    Gene Ontology Provided by RefSeq

    Function Evidence Code Pubs
    enables GTP binding IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    enables GTPase activator activity IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    enables GTPase activity IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    enables protein binding IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    Component Evidence Code Pubs
    located_in nucleus IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 

    General protein information

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    Preferred Names
    arf-GAP with GTPase, ANK repeat and PH domain-containing protein 2
    Names
    centaurin, gamma 1

    NCBI Reference Sequences (RefSeq)

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    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_001266854.1 → NP_001253783.1  arf-GAP with GTPase, ANK repeat and PH domain-containing protein 2

      See identical proteins and their annotated locations for NP_001253783.1

      Status: PROVISIONAL

      Source sequence(s)
      JV565062
      UniProtKB/TrEMBL
      H9F5U7, I2CTW2
      Related
      ENSMMUP00000066797.1, ENSMMUT00000093708.1
      Conserved Domains (6) summary
      cd04103
      Location:407 → 566
      Centaurin_gamma; Centaurin gamma (CENTG) GTPase
      PRK07764
      Location:83 → 174
      PRK07764; DNA polymerase III subunits gamma and tau; Validated
      cd01250
      Location:674 → 914
      PH_AGAP; Arf-GAP with GTPase, ANK repeat and PH domain-containing protein Pleckstrin homology (PH) domain
      sd00045
      Location:1058 → 1088
      ANK; ANK repeat [structural motif]
      cd08836
      Location:932 → 1039
      ArfGap_AGAP; ArfGAP with GTPase domain, ANK repeat and PH domains
      pfam12796
      Location:1058 → 1148
      Ank_2; Ankyrin repeats (3 copies)

    RefSeqs of Annotated Genomes: Macaca mulatta Annotation Release 103 details...Open this link in a new tab

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference Mmul_10 Primary Assembly

    Genomic

    1. NC_041764.1 Reference Mmul_10 Primary Assembly

      Range
      57309381..57327938 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_028829003.1 → XP_028684836.1  arf-GAP with GTPase, ANK repeat and PH domain-containing protein 2 isoform X3

      UniProtKB/TrEMBL
      F7HCX8, H9Z534
      Related
      ENSMMUP00000064510.1, ENSMMUT00000101730.1
      Conserved Domains (5) summary
      cd04103
      Location:71 → 230
      Centaurin_gamma; Centaurin gamma (CENTG) GTPase
      cd01250
      Location:338 → 558
      PH_AGAP; Arf-GAP with GTPase, ANK repeat and PH domain-containing protein Pleckstrin homology (PH) domain
      sd00045
      Location:702 → 732
      ANK; ANK repeat [structural motif]
      cd08836
      Location:576 → 683
      ArfGap_AGAP; ArfGAP with GTPase domain, ANK repeat and PH domains
      pfam12796
      Location:702 → 792
      Ank_2; Ankyrin repeats (3 copies)

    2. XM_028829002.1 → XP_028684835.1  arf-GAP with GTPase, ANK repeat and PH domain-containing protein 2 isoform X2

      UniProtKB/TrEMBL
      F7HCX8
      Conserved Domains (5) summary
      cd04103
      Location:71 → 230
      Centaurin_gamma; Centaurin gamma (CENTG) GTPase
      cd01250
      Location:338 → 578
      PH_AGAP; Arf-GAP with GTPase, ANK repeat and PH domain-containing protein Pleckstrin homology (PH) domain
      sd00045
      Location:722 → 752
      ANK; ANK repeat [structural motif]
      cd08836
      Location:596 → 703
      ArfGap_AGAP; ArfGAP with GTPase domain, ANK repeat and PH domains
      pfam12796
      Location:722 → 812
      Ank_2; Ankyrin repeats (3 copies)

    3. XM_028829001.1 → XP_028684834.1  arf-GAP with GTPase, ANK repeat and PH domain-containing protein 2 isoform X1

      UniProtKB/TrEMBL
      F7HCY1, H9F5U7
      Related
      ENSMMUP00000031206.4, ENSMMUT00000033343.4
      Conserved Domains (6) summary
      cd04103
      Location:407 → 566
      Centaurin_gamma; Centaurin gamma (CENTG) GTPase
      PRK07764
      Location:83 → 174
      PRK07764; DNA polymerase III subunits gamma and tau; Validated
      cd01250
      Location:674 → 894
      PH_AGAP; Arf-GAP with GTPase, ANK repeat and PH domain-containing protein Pleckstrin homology (PH) domain
      sd00045
      Location:1038 → 1068
      ANK; ANK repeat [structural motif]
      cd08836
      Location:912 → 1019
      ArfGap_AGAP; ArfGAP with GTPase domain, ANK repeat and PH domains
      pfam12796
      Location:1038 → 1128
      Ank_2; Ankyrin repeats (3 copies)
    Nucleotide Protein
    Heading Accession and Version

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