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    FLT4 fms related receptor tyrosine kinase 4 [ Macaca mulatta (Rhesus monkey) ]

    Gene ID: 716412, updated on 17-Aug-2024

    Summary

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    Official Symbol
    FLT4provided by VGNC
    Official Full Name
    fms related receptor tyrosine kinase 4provided by VGNC
    Primary source
    VGNC:VGNC:72681
    See related
    Ensembl:ENSMMUG00000018693
    Gene type
    protein coding
    RefSeq status
    MODEL
    Organism
    Macaca mulatta
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Cercopithecidae; Cercopithecinae; Macaca
    Orthologs
    human mouse all
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    Genomic context

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    See FLT4 in Genome Data Viewer
    Location:
    chromosome: 6
    Exon count:
    31
    Annotation release Status Assembly Chr Location
    103 current Mmul_10 (GCF_003339765.1) 6 NC_041759.1 (178021132..178066939, complement)
    102 previous assembly Mmul_8.0.1 (GCF_000772875.2) 6 NC_027898.1 (179330057..179376109, complement)

    Chromosome 6 - NC_041759.1Genomic Context describing neighboring genes Neighboring gene transcription initiation factor TFIID subunit 4-like Neighboring gene CCR4-NOT transcription complex subunit 6 Neighboring gene secretoglobin family 3A member 1 Neighboring gene olfactory receptor 2Y1-like Neighboring gene olfactory receptor, family 2, subfamily Y, member 1

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. A new rhesus macaque assembly and annotation for next-generation sequencing analyses. Zimin AV, et al. Biol Direct, 2014 Oct 14. PMID 25319552, Free PMC Article
    2. Manual GO annotation of predictive protein signatures: the InterPro approach to GO curation. Burge S, et al. Database (Oxford), 2012. PMID 22301074, Free PMC Article
    3. TreeGrafter: phylogenetic tree-based annotation of proteins with Gene Ontology terms and other annotations. Tang H, et al. Bioinformatics, 2019 Feb 1. PMID 30032202, Free PMC Article

    GeneRIFs: Gene References Into Functions

    General gene information

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    Homology

    Gene Ontology Provided by RefSeq

    Function Evidence Code Pubs
    enables ATP binding IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    enables transmembrane receptor protein tyrosine kinase activity IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    Process Evidence Code Pubs
    involved_in cell surface receptor protein tyrosine kinase signaling pathway IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    involved_in multicellular organism development IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    involved_in positive regulation of kinase activity IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    involved_in protein phosphorylation IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    Component Evidence Code Pubs
    part_of receptor complex IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 

    General protein information

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    Preferred Names
    vascular endothelial growth factor receptor 3
    Names
    fms related tyrosine kinase 4
    XP_014997135.2
    XP_014997136.2

    NCBI Reference Sequences (RefSeq)

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    RefSeqs of Annotated Genomes: Macaca mulatta Annotation Release 103 details...Open this link in a new tab

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference Mmul_10 Primary Assembly

    Genomic

    1. NC_041759.1 Reference Mmul_10 Primary Assembly

      Range
      178021132..178066939 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_015141649.2 → XP_014997135.2  vascular endothelial growth factor receptor 3 isoform X1

      UniProtKB/TrEMBL
      F6YJD2
      Related
      ENSMMUP00000024605.4, ENSMMUT00000026284.4
      Conserved Domains (5) summary
      cd05862
      Location:245 → 329
      Ig_VEGFR; Immunoglobulin (Ig)-like domain of vascular endothelial growth factor (VEGF) receptor(R)
      cd05863
      Location:352 → 418
      Ig_VEGFR-3; Immunoglobulin (Ig)-like domain of vascular endothelial growth factor receptor 3 (VEGFR-3)
      smart00408
      Location:693 → 755
      IGc2; Immunoglobulin C-2 Type
      pfam13927
      Location:559 → 656
      Ig_3; Immunoglobulin domain
      cl21453
      Location:837 → 1167
      PKc_like; Protein Kinases, catalytic domain

    2. XM_015141650.2 → XP_014997136.2  vascular endothelial growth factor receptor 3 isoform X2

      Conserved Domains (5) summary
      cd05862
      Location:245 → 329
      Ig_VEGFR; Immunoglobulin (Ig)-like domain of vascular endothelial growth factor (VEGF) receptor(R)
      cd05863
      Location:352 → 418
      Ig_VEGFR-3; Immunoglobulin (Ig)-like domain of vascular endothelial growth factor receptor 3 (VEGFR-3)
      smart00408
      Location:693 → 755
      IGc2; Immunoglobulin C-2 Type
      pfam13927
      Location:559 → 656
      Ig_3; Immunoglobulin domain
      cl21453
      Location:837 → 1167
      PKc_like; Protein Kinases, catalytic domain
    Nucleotide Protein
    Heading Accession and Version

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