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    SPEN spen family transcriptional repressor [ Macaca mulatta (Rhesus monkey) ]

    Gene ID: 696205, updated on 17-Aug-2024

    Summary

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    Official Symbol
    SPENprovided by VGNC
    Official Full Name
    spen family transcriptional repressorprovided by VGNC
    Primary source
    VGNC:VGNC:77940
    See related
    Ensembl:ENSMMUG00000008026
    Gene type
    protein coding
    RefSeq status
    MODEL
    Organism
    Macaca mulatta
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Cercopithecidae; Cercopithecinae; Macaca
    Orthologs
    human mouse all
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    Genomic context

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    See SPEN in Genome Data Viewer
    Location:
    chromosome: 1
    Exon count:
    15
    Annotation release Status Assembly Chr Location
    103 current Mmul_10 (GCF_003339765.1) 1 NC_041754.1 (208838220..208935989, complement)
    102 previous assembly Mmul_8.0.1 (GCF_000772875.2) 1 NC_027893.1 (14766790..14865998)

    Chromosome 1 - NC_041754.1Genomic Context describing neighboring genes Neighboring gene steroid receptor associated and regulated protein Neighboring gene zinc finger and BTB domain containing 17 Neighboring gene small nucleolar RNA U13 Neighboring gene uncharacterized LOC100423683 Neighboring gene beta-2-glycoprotein 1 pseudogene Neighboring gene 60S ribosomal protein L12 pseudogene

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. A new rhesus macaque assembly and annotation for next-generation sequencing analyses. Zimin AV, et al. Biol Direct, 2014 Oct 14. PMID 25319552, Free PMC Article
    2. TreeGrafter: phylogenetic tree-based annotation of proteins with Gene Ontology terms and other annotations. Tang H, et al. Bioinformatics, 2019 Feb 1. PMID 30032202, Free PMC Article

    GeneRIFs: Gene References Into Functions

    General gene information

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    Markers

    Homology

    Gene Ontology Provided by RefSeq

    Function Evidence Code Pubs
    enables mRNA binding IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    Process Evidence Code Pubs
    involved_in regulation of transcription by RNA polymerase II IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    Component Evidence Code Pubs
    located_in nucleus IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 

    General protein information

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    Preferred Names
    msx2-interacting protein
    Names
    msx2-interacting protein-like

    NCBI Reference Sequences (RefSeq)

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    RefSeqs of Annotated Genomes: Macaca mulatta Annotation Release 103 details...Open this link in a new tab

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference Mmul_10 Primary Assembly

    Genomic

    1. NC_041754.1 Reference Mmul_10 Primary Assembly

      Range
      208838220..208935989 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_002808274.3 → XP_002808320.3  msx2-interacting protein isoform X1

      UniProtKB/TrEMBL
      A0A1D5R6E8, H9FRK7
      Related
      ENSMMUP00000055886.2, ENSMMUT00000068265.2
      Conserved Domains (10) summary
      PTZ00121
      Location:776 → 1630
      PTZ00121; MAEBL; Provisional
      PHA03247
      Location:2947 → 3495
      PHA03247; large tegument protein UL36; Provisional
      PHA03307
      Location:2014 → 2338
      PHA03307; transcriptional regulator ICP4; Provisional
      COG0724
      Location:512 → 671
      RRM; RNA recognition motif (RRM) domain [Translation, ribosomal structure and biogenesis]
      PRK12323
      Location:1617 → 1804
      PRK12323; DNA polymerase III subunits gamma and tau; Provisional
      cd12348
      Location:7 → 81
      RRM1_SHARP; RNA recognition motif 1 in SMART/HDAC1-associated repressor protein (SHARP) and similar proteins
      cd12349
      Location:336 → 409
      RRM2_SHARP; RNA recognition motif 2 in SMART/HDAC1-associated repressor protein (SHARP) and similar proteins
      cd12350
      Location:436 → 509
      RRM3_SHARP; RNA recognition motif 3 in SMART/HDAC1-associated repressor protein (SHARP) and similar proteins
      cd12351
      Location:510 → 586
      RRM4_SHARP; RNA recognition motif 4 in SMART/HDAC1-associated repressor protein (SHARP) and similar proteins
      pfam07744
      Location:3510 → 3670
      SPOC; SPOC domain

    2. XM_015119868.2 → XP_014975354.2  msx2-interacting protein isoform X2

      UniProtKB/TrEMBL
      A0A5F7ZEA5
      Conserved Domains (8) summary
      PTZ00121
      Location:373 → 1227
      PTZ00121; MAEBL; Provisional
      PHA03247
      Location:2544 → 3092
      PHA03247; large tegument protein UL36; Provisional
      PHA03307
      Location:1611 → 1935
      PHA03307; transcriptional regulator ICP4; Provisional
      COG0724
      Location:109 → 268
      RRM; RNA recognition motif (RRM) domain [Translation, ribosomal structure and biogenesis]
      PRK12323
      Location:1214 → 1401
      PRK12323; DNA polymerase III subunits gamma and tau; Provisional
      cd12350
      Location:33 → 106
      RRM3_SHARP; RNA recognition motif 3 in SMART/HDAC1-associated repressor protein (SHARP) and similar proteins
      cd12351
      Location:107 → 183
      RRM4_SHARP; RNA recognition motif 4 in SMART/HDAC1-associated repressor protein (SHARP) and similar proteins
      pfam07744
      Location:3107 → 3267
      SPOC; SPOC domain
    Nucleotide Protein
    Heading Accession and Version

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