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    ARHGAP32 Rho GTPase activating protein 32 [ Macaca mulatta (Rhesus monkey) ]

    Gene ID: 718464, updated on 17-Aug-2024

    Summary

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    Official Symbol
    ARHGAP32provided by VGNC
    Official Full Name
    Rho GTPase activating protein 32provided by VGNC
    Primary source
    VGNC:VGNC:69855
    See related
    Ensembl:ENSMMUG00000002963
    Gene type
    protein coding
    RefSeq status
    MODEL
    Organism
    Macaca mulatta
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Cercopithecidae; Cercopithecinae; Macaca
    Orthologs
    human mouse all
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    Genomic context

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    See ARHGAP32 in Genome Data Viewer
    Location:
    chromosome: 14
    Exon count:
    28
    Annotation release Status Assembly Chr Location
    103 current Mmul_10 (GCF_003339765.1) 14 NC_041767.1 (121693094..121942894, complement)
    102 previous assembly Mmul_8.0.1 (GCF_000772875.2) 14 NC_027906.1 (121752443..121973448, complement)

    Chromosome 14 - NC_041767.1Genomic Context describing neighboring genes Neighboring gene potassium inwardly rectifying channel subfamily J member 1 Neighboring gene potassium inwardly rectifying channel subfamily J member 5 Neighboring gene tumor protein p53 regulated apoptosis inducing protein 1 Neighboring gene U6 spliceosomal RNA Neighboring gene cytochrome c oxidase subunit IV Neighboring gene U6 spliceosomal RNA Neighboring gene uncharacterized LOC106993545 Neighboring gene BARX homeobox 2 Neighboring gene uncharacterized LOC106993526

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. A new rhesus macaque assembly and annotation for next-generation sequencing analyses. Zimin AV, et al. Biol Direct, 2014 Oct 14. PMID 25319552, Free PMC Article
    2. Manual GO annotation of predictive protein signatures: the InterPro approach to GO curation. Burge S, et al. Database (Oxford), 2012. PMID 22301074, Free PMC Article
    3. TreeGrafter: phylogenetic tree-based annotation of proteins with Gene Ontology terms and other annotations. Tang H, et al. Bioinformatics, 2019 Feb 1. PMID 30032202, Free PMC Article

    GeneRIFs: Gene References Into Functions

    General gene information

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    Markers

    Homology

    Gene Ontology Provided by RefSeq

    Function Evidence Code Pubs
    enables GTPase activator activity IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    enables phosphatidylinositol phosphate binding IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    enables protein binding IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    Process Evidence Code Pubs
    involved_in small GTPase-mediated signal transduction IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    Component Evidence Code Pubs
    located_in Golgi apparatus IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    located_in actin cytoskeleton IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    located_in cell cortex IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    located_in fibrillar center IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    located_in nucleoplasm IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 

    General protein information

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    Preferred Names
    rho GTPase-activating protein 32

    NCBI Reference Sequences (RefSeq)

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    RefSeqs of Annotated Genomes: Macaca mulatta Annotation Release 103 details...Open this link in a new tab

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference Mmul_10 Primary Assembly

    Genomic

    1. NC_041767.1 Reference Mmul_10 Primary Assembly

      Range
      121693094..121942894 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_028834158.1 → XP_028689991.1  rho GTPase-activating protein 32 isoform X3

      UniProtKB/TrEMBL
      A0A5F8AFZ7
      Conserved Domains (3) summary
      cd07298
      Location:101 → 215
      PX_RICS; The phosphoinositide binding Phox Homology domain of PX-RICS
      cd11835
      Location:237 → 290
      SH3_ARHGAP32_33; Src homology 3 domain of Rho GTPase-activating proteins 32 and 33, and similar proteins
      cd04384
      Location:342 → 536
      RhoGAP_CdGAP; RhoGAP (GTPase-activator protein [GAP] for Rho-like small GTPases) domain of CdGAP-like proteins; CdGAP contains an N-terminal RhoGAP domain and a C-terminal proline-rich region, and it is active on both Cdc42 and Rac1 but not RhoA. CdGAP is recruited to ...

    2. XM_015116094.2 → XP_014971580.2  rho GTPase-activating protein 32 isoform X1

      UniProtKB/TrEMBL
      A0A5F8AFZ7
      Conserved Domains (3) summary
      cd07298
      Location:142 → 256
      PX_RICS; The phosphoinositide binding Phox Homology domain of PX-RICS
      cd11835
      Location:278 → 331
      SH3_ARHGAP32_33; Src homology 3 domain of Rho GTPase-activating proteins 32 and 33, and similar proteins
      cd04384
      Location:383 → 577
      RhoGAP_CdGAP; RhoGAP (GTPase-activator protein [GAP] for Rho-like small GTPases) domain of CdGAP-like proteins; CdGAP contains an N-terminal RhoGAP domain and a C-terminal proline-rich region, and it is active on both Cdc42 and Rac1 but not RhoA. CdGAP is recruited to ...

    3. XM_028834156.1 → XP_028689989.1  rho GTPase-activating protein 32 isoform X3

      UniProtKB/TrEMBL
      A0A5F8AFZ7
      Related
      ENSMMUP00000075860.1, ENSMMUT00000104654.1
      Conserved Domains (3) summary
      cd07298
      Location:101 → 215
      PX_RICS; The phosphoinositide binding Phox Homology domain of PX-RICS
      cd11835
      Location:237 → 290
      SH3_ARHGAP32_33; Src homology 3 domain of Rho GTPase-activating proteins 32 and 33, and similar proteins
      cd04384
      Location:342 → 536
      RhoGAP_CdGAP; RhoGAP (GTPase-activator protein [GAP] for Rho-like small GTPases) domain of CdGAP-like proteins; CdGAP contains an N-terminal RhoGAP domain and a C-terminal proline-rich region, and it is active on both Cdc42 and Rac1 but not RhoA. CdGAP is recruited to ...

    4. XM_028834157.1 → XP_028689990.1  rho GTPase-activating protein 32 isoform X3

      UniProtKB/TrEMBL
      A0A5F8AFZ7
      Conserved Domains (3) summary
      cd07298
      Location:101 → 215
      PX_RICS; The phosphoinositide binding Phox Homology domain of PX-RICS
      cd11835
      Location:237 → 290
      SH3_ARHGAP32_33; Src homology 3 domain of Rho GTPase-activating proteins 32 and 33, and similar proteins
      cd04384
      Location:342 → 536
      RhoGAP_CdGAP; RhoGAP (GTPase-activator protein [GAP] for Rho-like small GTPases) domain of CdGAP-like proteins; CdGAP contains an N-terminal RhoGAP domain and a C-terminal proline-rich region, and it is active on both Cdc42 and Rac1 but not RhoA. CdGAP is recruited to ...

    5. XM_015116096.2 → XP_014971582.2  rho GTPase-activating protein 32 isoform X2

      UniProtKB/TrEMBL
      A0A5F8AFZ7
      Conserved Domains (4) summary
      cd07298
      Location:123 → 237
      PX_RICS; The phosphoinositide binding Phox Homology domain of PX-RICS
      cd11835
      Location:259 → 312
      SH3_ARHGAP32_33; Src homology 3 domain of Rho GTPase-activating proteins 32 and 33, and similar proteins
      PHA03247
      Location:1197 → 1633
      PHA03247; large tegument protein UL36; Provisional
      cd04384
      Location:364 → 558
      RhoGAP_CdGAP; RhoGAP (GTPase-activator protein [GAP] for Rho-like small GTPases) domain of CdGAP-like proteins; CdGAP contains an N-terminal RhoGAP domain and a C-terminal proline-rich region, and it is active on both Cdc42 and Rac1 but not RhoA. CdGAP is recruited to ...

    6. XM_015116100.2 → XP_014971586.1  rho GTPase-activating protein 32 isoform X5

      UniProtKB/TrEMBL
      F7GXZ4
      Conserved Domains (3) summary
      cd07298
      Location:48 → 162
      PX_RICS; The phosphoinositide binding Phox Homology domain of PX-RICS
      cd11835
      Location:184 → 237
      SH3_ARHGAP32_33; Src homology 3 domain of Rho GTPase-activating proteins 32 and 33, and similar proteins
      cd04384
      Location:289 → 483
      RhoGAP_CdGAP; RhoGAP_CdGAP: RhoGAP (GTPase-activator protein [GAP] for Rho-like small GTPases) domain of CdGAP-like proteins; CdGAP contains an N-terminal RhoGAP domain and a C-terminal proline-rich region, and it is active on both Cdc42 and Rac1 but not RhoA. CdGAP ...

    7. XM_015116099.2 → XP_014971585.1  rho GTPase-activating protein 32 isoform X4

      UniProtKB/TrEMBL
      A0A5F8AFZ7
      Conserved Domains (3) summary
      cd07298
      Location:52 → 166
      PX_RICS; The phosphoinositide binding Phox Homology domain of PX-RICS
      cd11835
      Location:188 → 241
      SH3_ARHGAP32_33; Src homology 3 domain of Rho GTPase-activating proteins 32 and 33, and similar proteins
      cd04384
      Location:293 → 487
      RhoGAP_CdGAP; RhoGAP_CdGAP: RhoGAP (GTPase-activator protein [GAP] for Rho-like small GTPases) domain of CdGAP-like proteins; CdGAP contains an N-terminal RhoGAP domain and a C-terminal proline-rich region, and it is active on both Cdc42 and Rac1 but not RhoA. CdGAP ...

    8. XM_015116102.2 → XP_014971588.1  rho GTPase-activating protein 32 isoform X6

      UniProtKB/TrEMBL
      F7GXZ4
      Conserved Domains (1) summary
      cd04384
      Location:43 → 237
      RhoGAP_CdGAP; RhoGAP_CdGAP: RhoGAP (GTPase-activator protein [GAP] for Rho-like small GTPases) domain of CdGAP-like proteins; CdGAP contains an N-terminal RhoGAP domain and a C-terminal proline-rich region, and it is active on both Cdc42 and Rac1 but not RhoA. CdGAP ...

    9. XM_015116104.2 → XP_014971590.1  rho GTPase-activating protein 32 isoform X7

      UniProtKB/TrEMBL
      F7GXZ4
      Conserved Domains (1) summary
      cd04384
      Location:19 → 213
      RhoGAP_CdGAP; RhoGAP_CdGAP: RhoGAP (GTPase-activator protein [GAP] for Rho-like small GTPases) domain of CdGAP-like proteins; CdGAP contains an N-terminal RhoGAP domain and a C-terminal proline-rich region, and it is active on both Cdc42 and Rac1 but not RhoA. CdGAP ...
    Nucleotide Protein
    Heading Accession and Version

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