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    CHEK1 checkpoint kinase 1 [ Macaca mulatta (Rhesus monkey) ]

    Gene ID: 713358, updated on 5-Mar-2024

    Summary

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    Gene symbol
    CHEK1
    Gene description
    checkpoint kinase 1
    See related
    Ensembl:ENSMMUG00000010010
    Gene type
    protein coding
    RefSeq status
    MODEL
    Organism
    Macaca mulatta
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Cercopithecidae; Cercopithecinae; Macaca
    Orthologs
    human mouse all
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    Genomic context

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    See CHEK1 in Genome Data Viewer
    Location:
    chromosome: 14
    Exon count:
    15
    Annotation release Status Assembly Chr Location
    103 current Mmul_10 (GCF_003339765.1) 14 NC_041767.1 (118383684..118486455)
    102 previous assembly Mmul_8.0.1 (GCF_000772875.2) 14 NC_027906.1 (118342665..118375130)

    Chromosome 14 - NC_041767.1Genomic Context describing neighboring genes Neighboring gene U6 spliceosomal RNA Neighboring gene EI24 autophagy associated transmembrane protein Neighboring gene STT3 oligosaccharyltransferase complex catalytic subunit A Neighboring gene U2 spliceosomal RNA Neighboring gene acrosomal vesicle protein 1 Neighboring gene prostate and testis expressed 1 Neighboring gene prostate and testis expressed 2

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. A new rhesus macaque assembly and annotation for next-generation sequencing analyses. Zimin AV, et al. Biol Direct, 2014 Oct 14. PMID 25319552, Free PMC Article
    2. Manual GO annotation of predictive protein signatures: the InterPro approach to GO curation. Burge S, et al. Database (Oxford), 2012. PMID 22301074, Free PMC Article
    3. TreeGrafter: phylogenetic tree-based annotation of proteins with Gene Ontology terms and other annotations. Tang H, et al. Bioinformatics, 2019 Feb 1. PMID 30032202, Free PMC Article

    GeneRIFs: Gene References Into Functions

    General gene information

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    Markers

    Homology

    Gene Ontology Provided by RefSeq

    Function Evidence Code Pubs
    enables ATP binding IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    enables protein serine/threonine kinase activity IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    Process Evidence Code Pubs
    involved_in mitotic G2 DNA damage checkpoint signaling IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    involved_in protein phosphorylation IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    Component Evidence Code Pubs
    located_in cytoplasm IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    located_in nucleus IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    located_in site of double-strand break IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 

    General protein information

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    Preferred Names
    serine/threonine-protein kinase Chk1

    NCBI Reference Sequences (RefSeq)

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    RefSeqs of Annotated Genomes: Macaca mulatta Annotation Release 103 details...Open this link in a new tab

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference Mmul_10 Primary Assembly

    Genomic

    1. NC_041767.1 Reference Mmul_10 Primary Assembly

      Range
      118383684..118486455
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_028834138.1 → XP_028689971.1  serine/threonine-protein kinase Chk1 isoform X1

      UniProtKB/TrEMBL
      F6YCB3
      Related
      ENSMMUP00000036602.3, ENSMMUT00000043607.3
      Conserved Domains (1) summary
      cd14069
      Location:218 → 476
      STKc_Chk1; Catalytic domain of the Serine/Threonine kinase, Checkpoint kinase 1

    2. XM_001111431.4 → XP_001111431.4  serine/threonine-protein kinase Chk1 isoform X1

      UniProtKB/TrEMBL
      F6YCB3
      Conserved Domains (1) summary
      cd14069
      Location:218 → 476
      STKc_Chk1; Catalytic domain of the Serine/Threonine kinase, Checkpoint kinase 1

    3. XM_028834139.1 → XP_028689972.1  serine/threonine-protein kinase Chk1 isoform X2

      UniProtKB/TrEMBL
      F7DQ46, H9YYL0
      Related
      ENSMMUP00000011489.3, ENSMMUT00000012250.3
      Conserved Domains (1) summary
      cd14069
      Location:19 → 277
      STKc_Chk1; Catalytic domain of the Serine/Threonine kinase, Checkpoint kinase 1

    4. XM_028834140.1 → XP_028689973.1  serine/threonine-protein kinase Chk1 isoform X3

      UniProtKB/TrEMBL
      A0A5K1TVD8
      Conserved Domains (1) summary
      cd14069
      Location:7 → 265
      STKc_Chk1; Catalytic domain of the Serine/Threonine kinase, Checkpoint kinase 1
    Nucleotide Protein
    Heading Accession and Version

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