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    CLCN3 chloride voltage-gated channel 3 [ Macaca mulatta (Rhesus monkey) ]

    Gene ID: 694472, updated on 17-Aug-2024

    Summary

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    Official Symbol
    CLCN3provided by VGNC
    Official Full Name
    chloride voltage-gated channel 3provided by VGNC
    Primary source
    VGNC:VGNC:71236
    See related
    Ensembl:ENSMMUG00000010228
    Gene type
    protein coding
    RefSeq status
    MODEL
    Organism
    Macaca mulatta
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Cercopithecidae; Cercopithecinae; Macaca
    Orthologs
    human mouse all
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    Genomic context

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    See CLCN3 in Genome Data Viewer
    Location:
    chromosome: 5
    Exon count:
    15
    Annotation release Status Assembly Chr Location
    103 current Mmul_10 (GCF_003339765.1) 5 NC_041758.1 (166926472..167028107)
    102 previous assembly Mmul_8.0.1 (GCF_000772875.2) 5 NC_027897.1 (169834713..169944460)

    Chromosome 5 - NC_041758.1Genomic Context describing neighboring genes Neighboring gene SH3 domain containing ring finger 1 Neighboring gene NIMA related kinase 1 Neighboring gene histone PARylation factor 1 Neighboring gene prostaglandin E synthase 3 pseudogene

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. Manual GO annotation of predictive protein signatures: the InterPro approach to GO curation. Burge S, et al. Database (Oxford), 2012. PMID 22301074, Free PMC Article
    2. TreeGrafter: phylogenetic tree-based annotation of proteins with Gene Ontology terms and other annotations. Tang H, et al. Bioinformatics, 2019 Feb 1. PMID 30032202, Free PMC Article

    GeneRIFs: Gene References Into Functions

    General gene information

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    Markers

    Homology

    Gene Ontology Provided by RefSeq

    Function Evidence Code Pubs
    enables voltage-gated chloride channel activity IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    Process Evidence Code Pubs
    involved_in chloride transport IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    involved_in transmembrane transport IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    Component Evidence Code Pubs
    located_in Golgi apparatus IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    located_in early endosome IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    located_in membrane IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    located_in synaptic vesicle IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 

    General protein information

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    Preferred Names
    H(+)/Cl(-) exchange transporter 3

    NCBI Reference Sequences (RefSeq)

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    RefSeqs of Annotated Genomes: Macaca mulatta Annotation Release 103 details...Open this link in a new tab

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference Mmul_10 Primary Assembly

    Genomic

    1. NC_041758.1 Reference Mmul_10 Primary Assembly

      Range
      166926472..167028107
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_015139495.2 → XP_014994981.1  H(+)/Cl(-) exchange transporter 3 isoform X1

      UniProtKB/TrEMBL
      F6S3L2, H9EPI1, H9YYH2
      Related
      ENSMMUP00000013392.4, ENSMMUT00000014298.4
      Conserved Domains (2) summary
      cd03684
      Location:136 → 642
      ClC_3_like; ClC-3-like chloride channel proteins. This CD includes ClC-3, ClC-4, ClC-5 and ClC-Y1. ClC-3 was initially cloned from rat kidney. Expression of ClC-3 produces outwardly-rectifying Cl currents that are inhibited by protein kinase C activation. It has ...
      cd04591
      Location:653 → 803
      CBS_pair_voltage-gated_CLC_euk_bac; Two tandem repeats of the cystathionine beta-synthase (CBS pair) domains associated with the voltage gated CLC (chloride channel) in eukaryotes and bacteria

    2. XM_015139499.2 → XP_014994985.1  H(+)/Cl(-) exchange transporter 3 isoform X3

      UniProtKB/TrEMBL
      A0A1D5QNR1, H9EPI2, H9YYH3
      Related
      ENSMMUP00000049687.2, ENSMMUT00000054195.2
      Conserved Domains (2) summary
      cd03684
      Location:136 → 642
      ClC_3_like; ClC-3-like chloride channel proteins. This CD includes ClC-3, ClC-4, ClC-5 and ClC-Y1. ClC-3 was initially cloned from rat kidney. Expression of ClC-3 produces outwardly-rectifying Cl currents that are inhibited by protein kinase C activation. It has ...
      cd04591
      Location:653 → 803
      CBS_pair_voltage-gated_CLC_euk_bac; Two tandem repeats of the cystathionine beta-synthase (CBS pair) domains associated with the voltage gated CLC (chloride channel) in eukaryotes and bacteria

    3. XM_015139497.2 → XP_014994983.1  H(+)/Cl(-) exchange transporter 3 isoform X2

      UniProtKB/TrEMBL
      H9YYH2
      Related
      ENSMMUP00000048797.2, ENSMMUT00000077657.2
      Conserved Domains (2) summary
      cd03684
      Location:109 → 615
      ClC_3_like; ClC-3-like chloride channel proteins. This CD includes ClC-3, ClC-4, ClC-5 and ClC-Y1. ClC-3 was initially cloned from rat kidney. Expression of ClC-3 produces outwardly-rectifying Cl currents that are inhibited by protein kinase C activation. It has ...
      cd04591
      Location:626 → 776
      CBS_pair_voltage-gated_CLC_euk_bac; Two tandem repeats of the cystathionine beta-synthase (CBS pair) domains associated with the voltage gated CLC (chloride channel) in eukaryotes and bacteria

    4. XM_015139501.2 → XP_014994987.1  H(+)/Cl(-) exchange transporter 3 isoform X4

      UniProtKB/TrEMBL
      A0A1D5Q4G1, H9YYH3
      Related
      ENSMMUP00000042925.2, ENSMMUT00000071924.2
      Conserved Domains (2) summary
      cd03684
      Location:109 → 615
      ClC_3_like; ClC-3-like chloride channel proteins. This CD includes ClC-3, ClC-4, ClC-5 and ClC-Y1. ClC-3 was initially cloned from rat kidney. Expression of ClC-3 produces outwardly-rectifying Cl currents that are inhibited by protein kinase C activation. It has ...
      cd04591
      Location:626 → 776
      CBS_pair_voltage-gated_CLC_euk_bac; Two tandem repeats of the cystathionine beta-synthase (CBS pair) domains associated with the voltage gated CLC (chloride channel) in eukaryotes and bacteria
    Nucleotide Protein
    Heading Accession and Version

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