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    FBXW7 F-box and WD repeat domain containing 7 [ Macaca mulatta (Rhesus monkey) ]

    Gene ID: 695101, updated on 17-Aug-2024

    Summary

    Official Symbol
    FBXW7provided by VGNC
    Official Full Name
    F-box and WD repeat domain containing 7provided by VGNC
    Primary source
    VGNC:VGNC:72516
    See related
    Ensembl:ENSMMUG00000020330
    Gene type
    protein coding
    RefSeq status
    PROVISIONAL
    Organism
    Macaca mulatta
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Cercopithecidae; Cercopithecinae; Macaca
    Orthologs
    NEW
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    Genomic context

    See FBXW7 in Genome Data Viewer
    Location:
    chromosome: 5
    Exon count:
    16
    Annotation release Status Assembly Chr Location
    103 current Mmul_10 (GCF_003339765.1) 5 NC_041758.1 (149971005..150180717, complement)
    102 previous assembly Mmul_8.0.1 (GCF_000772875.2) 5 NC_027897.1 (152241055..152450787, complement)

    Chromosome 5 - NC_041758.1Genomic Context describing neighboring genes Neighboring gene uncharacterized LOC114678186 Neighboring gene uncharacterized LOC106998538 Neighboring gene microRNA mir-3140 Neighboring gene uncharacterized LOC696812 Neighboring gene 40S ribosomal protein S3a pseudogene

    Genomic regions, transcripts, and products

    General gene information

    Markers

    Gene Ontology Provided by RefSeq

    Function Evidence Code Pubs
    enables ubiquitin binding IEA
    Inferred from Electronic Annotation
    more info
    PubMed 
    Process Evidence Code Pubs
    involved_in proteasome-mediated ubiquitin-dependent protein catabolic process IEA
    Inferred from Electronic Annotation
    more info
    PubMed 
    involved_in ubiquitin recycling IEA
    Inferred from Electronic Annotation
    more info
    PubMed 
    Component Evidence Code Pubs
    located_in cytoplasm IEA
    Inferred from Electronic Annotation
    more info
    PubMed 
    located_in nucleus IEA
    Inferred from Electronic Annotation
    more info
    PubMed 

    General protein information

    Preferred Names
    F-box/WD repeat-containing protein 7
    Names
    F-box and WD repeat domain containing 7, E3 ubiquitin protein ligase

    NCBI Reference Sequences (RefSeq)

    NEW Try the new Transcript table

    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_001257948.2NP_001244877.1  F-box/WD repeat-containing protein 7

      See identical proteins and their annotated locations for NP_001244877.1

      Status: PROVISIONAL

      Source sequence(s)
      JU335305
      UniProtKB/TrEMBL
      A0A1D5Q962, G7MS47
      Related
      ENSMMUP00000044580.1, ENSMMUT00000073363.2
      Conserved Domains (3) summary
      cd00200
      Location:374650
      WD40; WD40 domain, found in a number of eukaryotic proteins that cover a wide variety of functions including adaptor/regulatory modules in signal transduction, pre-mRNA processing and cytoskeleton assembly; typically contains a GH dipeptide 11-24 residues from ...
      sd00039
      Location:384419
      7WD40; WD40 repeat [structural motif]
      pfam12937
      Location:281325
      F-box-like

    RefSeqs of Annotated Genomes: Macaca mulatta Annotation Release 103 details...Open this link in a new tab

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference Mmul_10 Primary Assembly

    Genomic

    1. NC_041758.1 Reference Mmul_10 Primary Assembly

      Range
      149971005..150180717 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_015139321.2XP_014994807.1  F-box/WD repeat-containing protein 7 isoform X2

      UniProtKB/TrEMBL
      F6WGU1
      Related
      ENSMMUP00000026757.4, ENSMMUT00000028597.4
      Conserved Domains (4) summary
      COG2319
      Location:339679
      WD40; WD40 repeat [General function prediction only]
      cd00200
      Location:346622
      WD40; WD40 domain, found in a number of eukaryotic proteins that cover a wide variety of functions including adaptor/regulatory modules in signal transduction, pre-mRNA processing and cytoskeleton assembly; typically contains a GH dipeptide 11-24 residues from ...
      pfam12937
      Location:253297
      F-box-like; F-box-like
      sd00039
      Location:356391
      7WD40; WD40 repeat [structural motif]
    2. XM_015139318.2XP_014994804.1  F-box/WD repeat-containing protein 7 isoform X1

      UniProtKB/TrEMBL
      A0A1D5Q962, G7MS47
      Conserved Domains (3) summary
      cd00200
      Location:374650
      WD40; WD40 domain, found in a number of eukaryotic proteins that cover a wide variety of functions including adaptor/regulatory modules in signal transduction, pre-mRNA processing and cytoskeleton assembly; typically contains a GH dipeptide 11-24 residues from ...
      sd00039
      Location:384419
      7WD40; WD40 repeat [structural motif]
      pfam12937
      Location:281325
      F-box-like
    3. XM_015139317.2XP_014994803.1  F-box/WD repeat-containing protein 7 isoform X1

      UniProtKB/TrEMBL
      A0A1D5Q962, G7MS47
      Conserved Domains (3) summary
      cd00200
      Location:374650
      WD40; WD40 domain, found in a number of eukaryotic proteins that cover a wide variety of functions including adaptor/regulatory modules in signal transduction, pre-mRNA processing and cytoskeleton assembly; typically contains a GH dipeptide 11-24 residues from ...
      sd00039
      Location:384419
      7WD40; WD40 repeat [structural motif]
      pfam12937
      Location:281325
      F-box-like
    4. XM_015139316.2XP_014994802.1  F-box/WD repeat-containing protein 7 isoform X1

      UniProtKB/TrEMBL
      A0A1D5Q962, G7MS47
      Conserved Domains (3) summary
      cd00200
      Location:374650
      WD40; WD40 domain, found in a number of eukaryotic proteins that cover a wide variety of functions including adaptor/regulatory modules in signal transduction, pre-mRNA processing and cytoskeleton assembly; typically contains a GH dipeptide 11-24 residues from ...
      sd00039
      Location:384419
      7WD40; WD40 repeat [structural motif]
      pfam12937
      Location:281325
      F-box-like
    5. XM_015139322.2XP_014994808.2  F-box/WD repeat-containing protein 7 isoform X3

      UniProtKB/TrEMBL
      F6WGU9, H9FWQ0
      Related
      ENSMMUP00000026756.4, ENSMMUT00000028596.4
      Conserved Domains (3) summary
      cd00200
      Location:294570
      WD40; WD40 domain, found in a number of eukaryotic proteins that cover a wide variety of functions including adaptor/regulatory modules in signal transduction, pre-mRNA processing and cytoskeleton assembly; typically contains a GH dipeptide 11-24 residues from ...
      sd00039
      Location:304339
      7WD40; WD40 repeat [structural motif]
      pfam12937
      Location:201245
      F-box-like
    6. XM_015139319.2XP_014994805.1  F-box/WD repeat-containing protein 7 isoform X1

      UniProtKB/TrEMBL
      A0A1D5Q962, G7MS47
      Conserved Domains (3) summary
      cd00200
      Location:374650
      WD40; WD40 domain, found in a number of eukaryotic proteins that cover a wide variety of functions including adaptor/regulatory modules in signal transduction, pre-mRNA processing and cytoskeleton assembly; typically contains a GH dipeptide 11-24 residues from ...
      sd00039
      Location:384419
      7WD40; WD40 repeat [structural motif]
      pfam12937
      Location:281325
      F-box-like