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    GNAO1 G protein subunit alpha o1 [ Macaca mulatta (Rhesus monkey) ]

    Gene ID: 574394, updated on 17-Aug-2024

    Summary

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    Official Symbol
    GNAO1provided by VGNC
    Official Full Name
    G protein subunit alpha o1provided by VGNC
    Primary source
    VGNC:VGNC:73092
    See related
    Ensembl:ENSMMUG00000019900
    Gene type
    protein coding
    RefSeq status
    VALIDATED
    Organism
    Macaca mulatta
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Cercopithecidae; Cercopithecinae; Macaca
    Also known as
    Gnao
    Orthologs
    human mouse all
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    Genomic context

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    See GNAO1 in Genome Data Viewer
    Location:
    chromosome: 20
    Exon count:
    11
    Annotation release Status Assembly Chr Location
    103 current Mmul_10 (GCF_003339765.1) 20 NC_041773.1 (43392689..43559583)
    102 previous assembly Mmul_8.0.1 (GCF_000772875.2) 20 NC_027912.1 (40322642..40489363)

    Chromosome 20 - NC_041773.1Genomic Context describing neighboring genes Neighboring gene carboxylesterase 5A Neighboring gene uncharacterized LOC106995032 Neighboring gene autocrine motility factor receptor Neighboring gene nudix hydrolase 21

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. Elevated gene expression levels distinguish human from non-human primate brains. Cáceres M, et al. Proc Natl Acad Sci U S A, 2003 Oct 28. PMID 14557539, Free PMC Article
    2. Analysis of the Macaca mulatta transcriptome and the sequence divergence between Macaca and human. Magness CL, et al. Genome Biol, 2005. PMID 15998449, Free PMC Article
    3. A new rhesus macaque assembly and annotation for next-generation sequencing analyses. Zimin AV, et al. Biol Direct, 2014 Oct 14. PMID 25319552, Free PMC Article
    4. Manual GO annotation of predictive protein signatures: the InterPro approach to GO curation. Burge S, et al. Database (Oxford), 2012. PMID 22301074, Free PMC Article
    5. TreeGrafter: phylogenetic tree-based annotation of proteins with Gene Ontology terms and other annotations. Tang H, et al. Bioinformatics, 2019 Feb 1. PMID 30032202, Free PMC Article

    GeneRIFs: Gene References Into Functions

    General gene information

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    Markers

    Homology

    Gene Ontology Provided by RefSeq

    Function Evidence Code Pubs
    enables G protein-coupled serotonin receptor binding IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    enables G-protein beta/gamma-subunit complex binding IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    enables GTP binding IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    enables GTPase activity IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    enables corticotropin-releasing hormone receptor 1 binding IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    enables mu-type opioid receptor binding IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    Process Evidence Code Pubs
    involved_in G protein-coupled dopamine receptor signaling pathway IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    involved_in adenylate cyclase-modulating G protein-coupled receptor signaling pathway IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    Component Evidence Code Pubs
    part_of heterotrimeric G-protein complex IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 

    General protein information

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    Preferred Names
    guanine nucleotide-binding protein G(o) subunit alpha

    NCBI Reference Sequences (RefSeq)

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    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_001195429.1 → NP_001182358.1  guanine nucleotide-binding protein G(o) subunit alpha

      See identical proteins and their annotated locations for NP_001182358.1

      Status: VALIDATED

      Source sequence(s)
      CN641989, CN641998, QNVO02000291
      UniProtKB/TrEMBL
      A0A5F8AB77, F7GQC3, F7GQC5
      Related
      ENSMMUP00000026158.2, ENSMMUT00000027960.4
      Conserved Domains (1) summary
      cd00066
      Location:34 → 348
      G-alpha; Alpha subunit of G proteins (guanine nucleotide binding)

    RefSeqs of Annotated Genomes: Macaca mulatta Annotation Release 103 details...Open this link in a new tab

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference Mmul_10 Primary Assembly

    Genomic

    1. NC_041773.1 Reference Mmul_10 Primary Assembly

      Range
      43392689..43559583
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_015126153.2 → XP_014981639.1  guanine nucleotide-binding protein G(o) subunit alpha isoform X1

      UniProtKB/TrEMBL
      A0A5F8AB77, F7GQC3, F7GQC5
      Related
      ENSMMUP00000026159.4, ENSMMUT00000027961.4
      Conserved Domains (1) summary
      cd00066
      Location:34 → 348
      G-alpha; Alpha subunit of G proteins (guanine nucleotide binding)

    2. XM_015126154.2 → XP_014981640.1  guanine nucleotide-binding protein G(o) subunit alpha isoform X2

      UniProtKB/TrEMBL
      A0A5F7ZR76, A0A5F8AB77
      Related
      ENSMMUP00000067654.1, ENSMMUT00000110266.1
      Conserved Domains (2) summary
      cd00066
      Location:34 → 348
      G-alpha; Alpha subunit of G proteins (guanine nucleotide binding)
      smart00275
      Location:14 → 352
      G_alpha; G protein alpha subunit
    Nucleotide Protein
    Heading Accession and Version

    Gene LinkOut

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