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    PDZRN3 PDZ domain containing ring finger 3 [ Macaca mulatta (Rhesus monkey) ]

    Gene ID: 709901, updated on 17-Aug-2024

    Summary

    Official Symbol
    PDZRN3provided by VGNC
    Official Full Name
    PDZ domain containing ring finger 3provided by VGNC
    Primary source
    VGNC:VGNC:75820
    See related
    Ensembl:ENSMMUG00000012661
    Gene type
    protein coding
    RefSeq status
    MODEL
    Organism
    Macaca mulatta
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Cercopithecidae; Cercopithecinae; Macaca
    Orthologs
    NEW
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    Try the new Transcript table

    Genomic context

    See PDZRN3 in Genome Data Viewer
    Location:
    chromosome: 2
    Exon count:
    13
    Annotation release Status Assembly Chr Location
    103 current Mmul_10 (GCF_003339765.1) 2 NC_041755.1 (129500418..129740849, complement)
    102 previous assembly Mmul_8.0.1 (GCF_000772875.2) 2 NC_027894.1 (68315885..68555988)

    Chromosome 2 - NC_041755.1Genomic Context describing neighboring genes Neighboring gene G patch domain-containing protein 11-like Neighboring gene U6 spliceosomal RNA Neighboring gene uncharacterized LOC114676382 Neighboring gene uncharacterized LOC106996858 Neighboring gene uncharacterized LOC106996859 Neighboring gene heat shock protein HSP 90-beta-like Neighboring gene aldose reductase pseudogene

    Genomic regions, transcripts, and products

    General gene information

    Markers

    Gene Ontology Provided by RefSeq

    Function Evidence Code Pubs
    enables protein binding IEA
    Inferred from Electronic Annotation
    more info
    PubMed 
    enables ubiquitin protein ligase activity IEA
    Inferred from Electronic Annotation
    more info
    PubMed 
    enables zinc ion binding IEA
    Inferred from Electronic Annotation
    more info
    PubMed 
    Process Evidence Code Pubs
    involved_in neuromuscular junction development IEA
    Inferred from Electronic Annotation
    more info
    PubMed 
    involved_in protein ubiquitination IEA
    Inferred from Electronic Annotation
    more info
    PubMed 
    Component Evidence Code Pubs
    located_in neuromuscular junction IEA
    Inferred from Electronic Annotation
    more info
    PubMed 

    General protein information

    Preferred Names
    E3 ubiquitin-protein ligase PDZRN3

    NCBI Reference Sequences (RefSeq)

    NEW Try the new Transcript table

    RefSeqs of Annotated Genomes: Macaca mulatta Annotation Release 103 details...Open this link in a new tab

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference Mmul_10 Primary Assembly

    Genomic

    1. NC_041755.1 Reference Mmul_10 Primary Assembly

      Range
      129500418..129740849 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_028844367.1XP_028700200.1  E3 ubiquitin-protein ligase PDZRN3 isoform X2

      UniProtKB/TrEMBL
      F7E722, G7MKV8
      Related
      ENSMMUP00000016634.4, ENSMMUT00000017761.4
      Conserved Domains (5) summary
      smart00228
      Location:245309
      PDZ; Domain present in PSD-95, Dlg, and ZO-1/2
      cd00992
      Location:391459
      PDZ_signaling; PDZ domain found in a variety of Eumetazoan signaling molecules, often in tandem arrangements. May be responsible for specific protein-protein interactions, as most PDZ domains bind C-terminal polypeptides, and binding to internal (non-C-terminal) ...
      cd00162
      Location:1856
      RING_Ubox; RING-HC finger (C3HC4-type) [structural motif]
      cl17238
      Location:1758
      RING_Ubox; The superfamily of RING finger (Really Interesting New Gene) domain and U-box domain
      cl19105
      Location:69132
      Sina; Seven in absentia (Sina) protein family, C-terminal substrate binding domain; composed of the Drosophila Sina protein, the mammalian Sina homolog (Siah), the plant protein SINAT5, and similar proteins. Sina, Siah and SINAT5 are RING-containing proteins ...
    2. XM_001098466.4XP_001098466.2  E3 ubiquitin-protein ligase PDZRN3 isoform X1

      See identical proteins and their annotated locations for XP_001098466.2

      UniProtKB/TrEMBL
      F7E732, G7MKV8
      Related
      ENSMMUP00000016631.2, ENSMMUT00000017758.4
      Conserved Domains (4) summary
      smart00228
      Location:246338
      PDZ; Domain present in PSD-95, Dlg, and ZO-1/2
      cd00162
      Location:1757
      RING; RING-finger (Really Interesting New Gene) domain, a specialized type of Zn-finger of 40 to 60 residues that binds two atoms of zinc; defined by the 'cross-brace' motif C-X2-C-X(9-39)-C-X(1-3)- H-X(2-3)-(N/C/H)-X2-C-X(4-48)C-X2-C; probably involved in ...
      cd00992
      Location:420488
      PDZ_signaling; PDZ domain found in a variety of Eumetazoan signaling molecules, often in tandem arrangements. May be responsible for specific protein-protein interactions, as most PDZ domains bind C-terminal polypeptides, and binding to internal (non-C-terminal) ...
      cl19105
      Location:69132
      Sina; Seven in absentia (Sina) protein family, C-terminal substrate binding domain; composed of the Drosophila Sina protein, the mammalian Sina homolog (Siah), the plant protein SINAT5, and similar proteins. Sina, Siah and SINAT5 are RING-containing proteins ...
    3. XM_015130386.2XP_014985872.1  E3 ubiquitin-protein ligase PDZRN3 isoform X4

      UniProtKB/TrEMBL
      A0A5F8A5K1
      Conserved Domains (2) summary
      smart00228
      Location:536
      PDZ; Domain present in PSD-95, Dlg, and ZO-1/2
      cd00992
      Location:118186
      PDZ_signaling; PDZ domain found in a variety of Eumetazoan signaling molecules, often in tandem arrangements. May be responsible for specific protein-protein interactions, as most PDZ domains bind C-terminal polypeptides, and binding to internal (non-C-terminal) ...
    4. XM_015130387.2XP_014985873.1  E3 ubiquitin-protein ligase PDZRN3 isoform X5

      UniProtKB/TrEMBL
      A0A5F8A5K1, F7E7H7
      Related
      ENSMMUP00000016629.4, ENSMMUT00000017756.4
      Conserved Domains (1) summary
      cd00992
      Location:77145
      PDZ_signaling; PDZ domain found in a variety of Eumetazoan signaling molecules, often in tandem arrangements. May be responsible for specific protein-protein interactions, as most PDZ domains bind C-terminal polypeptides, and binding to internal (non-C-terminal) ...
    5. XM_015130388.2XP_014985874.1  E3 ubiquitin-protein ligase PDZRN3 isoform X3

      UniProtKB/TrEMBL
      A0A5F8A5K1
      Conserved Domains (2) summary
      cd00992
      Location:137205
      PDZ_signaling; PDZ domain found in a variety of Eumetazoan signaling molecules, often in tandem arrangements. May be responsible for specific protein-protein interactions, as most PDZ domains bind C-terminal polypeptides, and binding to internal (non-C-terminal) ...
      cl00117
      Location:2053
      PDZ; PDZ domain, also called DHR (Dlg homologous region) or GLGF (after a conserved sequence motif). Many PDZ domains bind C-terminal polypeptides, though binding to internal (non-C-terminal) polypeptides and even to lipids has been demonstrated. ...