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    ADAM15 ADAM metallopeptidase domain 15 [ Macaca mulatta (Rhesus monkey) ]

    Gene ID: 719030, updated on 17-Aug-2024

    Summary

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    Official Symbol
    ADAM15provided by VGNC
    Official Full Name
    ADAM metallopeptidase domain 15provided by VGNC
    Primary source
    VGNC:VGNC:69477
    See related
    Ensembl:ENSMMUG00000023340
    Gene type
    protein coding
    RefSeq status
    MODEL
    Organism
    Macaca mulatta
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Cercopithecidae; Cercopithecinae; Macaca
    Orthologs
    human mouse all
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    Genomic context

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    See ADAM15 in Genome Data Viewer
    Location:
    chromosome: 1
    Exon count:
    28
    Annotation release Status Assembly Chr Location
    103 current Mmul_10 (GCF_003339765.1) 1 NC_041754.1 (95969617..95981161, complement)
    102 previous assembly Mmul_8.0.1 (GCF_000772875.2) 1 NC_027893.1 (129745601..129757145)

    Chromosome 1 - NC_041754.1Genomic Context describing neighboring genes Neighboring gene 60S ribosomal protein L10-like Neighboring gene ephrin A4 Neighboring gene DC-STAMP domain containing 1 Neighboring gene DC-STAMP domain containing 2 Neighboring gene zinc finger and BTB domain containing 7B

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. A new rhesus macaque assembly and annotation for next-generation sequencing analyses. Zimin AV, et al. Biol Direct, 2014 Oct 14. PMID 25319552, Free PMC Article
    2. Manual GO annotation of predictive protein signatures: the InterPro approach to GO curation. Burge S, et al. Database (Oxford), 2012. PMID 22301074, Free PMC Article
    3. TreeGrafter: phylogenetic tree-based annotation of proteins with Gene Ontology terms and other annotations. Tang H, et al. Bioinformatics, 2019 Feb 1. PMID 30032202, Free PMC Article

    GeneRIFs: Gene References Into Functions

    General gene information

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    Markers

    Homology

    Gene Ontology Provided by RefSeq

    Function Evidence Code Pubs
    enables integrin binding IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    enables metalloendopeptidase activity IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    Process Evidence Code Pubs
    involved_in innate immune response IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    involved_in integrin-mediated signaling pathway IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    involved_in proteolysis IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    Component Evidence Code Pubs
    located_in extracellular space IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 

    General protein information

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    Preferred Names
    disintegrin and metalloproteinase domain-containing protein 15

    NCBI Reference Sequences (RefSeq)

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    RefSeqs of Annotated Genomes: Macaca mulatta Annotation Release 103 details...Open this link in a new tab

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference Mmul_10 Primary Assembly

    Genomic

    1. NC_041754.1 Reference Mmul_10 Primary Assembly

      Range
      95969617..95981161 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_015110973.1 → XP_014966459.1  disintegrin and metalloproteinase domain-containing protein 15 isoform X6

      UniProtKB/TrEMBL
      H9G1A1
      Related
      ENSMMUP00000030730.4, ENSMMUT00000032844.4
      Conserved Domains (5) summary
      smart00050
      Location:431 → 504
      DISIN; Homologues of snake disintegrins
      smart00608
      Location:509 → 650
      ACR; ADAM Cysteine-Rich Domain
      cd04269
      Location:214 → 412
      ZnMc_adamalysin_II_like; Zinc-dependent metalloprotease; adamalysin_II_like subfamily. Adamalysin II is a snake venom zinc endopeptidase. This subfamily contains other snake venom metalloproteinases, as well as membrane-anchored metalloproteases belonging to the ADAM family. ...
      pfam01421
      Location:214 → 419
      Reprolysin; Reprolysin (M12B) family zinc metalloprotease
      pfam01562
      Location:62 → 154
      Pep_M12B_propep; Reprolysin family propeptide

    2. XM_015110958.1 → XP_014966444.1  disintegrin and metalloproteinase domain-containing protein 15 isoform X4

      UniProtKB/TrEMBL
      F7ED22
      Conserved Domains (5) summary
      smart00050
      Location:431 → 504
      DISIN; Homologues of snake disintegrins
      smart00608
      Location:509 → 650
      ACR; ADAM Cysteine-Rich Domain
      cd04269
      Location:214 → 412
      ZnMc_adamalysin_II_like; Zinc-dependent metalloprotease; adamalysin_II_like subfamily. Adamalysin II is a snake venom zinc endopeptidase. This subfamily contains other snake venom metalloproteinases, as well as membrane-anchored metalloproteases belonging to the ADAM family. ...
      pfam01421
      Location:214 → 419
      Reprolysin; Reprolysin (M12B) family zinc metalloprotease
      pfam01562
      Location:62 → 154
      Pep_M12B_propep; Reprolysin family propeptide

    3. XM_015110950.1 → XP_014966436.1  disintegrin and metalloproteinase domain-containing protein 15 isoform X2

      UniProtKB/TrEMBL
      H9G1A3
      Conserved Domains (5) summary
      smart00050
      Location:431 → 504
      DISIN; Homologues of snake disintegrins
      smart00608
      Location:509 → 650
      ACR; ADAM Cysteine-Rich Domain
      cd04269
      Location:214 → 412
      ZnMc_adamalysin_II_like; Zinc-dependent metalloprotease; adamalysin_II_like subfamily. Adamalysin II is a snake venom zinc endopeptidase. This subfamily contains other snake venom metalloproteinases, as well as membrane-anchored metalloproteases belonging to the ADAM family. ...
      pfam01421
      Location:214 → 419
      Reprolysin; Reprolysin (M12B) family zinc metalloprotease
      pfam01562
      Location:62 → 154
      Pep_M12B_propep; Reprolysin family propeptide

    4. XM_015110956.1 → XP_014966442.1  disintegrin and metalloproteinase domain-containing protein 15 isoform X3

      UniProtKB/TrEMBL
      F7ED22
      Related
      ENSMMUP00000030723.4, ENSMMUT00000032837.4
      Conserved Domains (5) summary
      smart00050
      Location:431 → 504
      DISIN; Homologues of snake disintegrins
      smart00608
      Location:509 → 650
      ACR; ADAM Cysteine-Rich Domain
      cd04269
      Location:214 → 412
      ZnMc_adamalysin_II_like; Zinc-dependent metalloprotease; adamalysin_II_like subfamily. Adamalysin II is a snake venom zinc endopeptidase. This subfamily contains other snake venom metalloproteinases, as well as membrane-anchored metalloproteases belonging to the ADAM family. ...
      pfam01421
      Location:214 → 419
      Reprolysin; Reprolysin (M12B) family zinc metalloprotease
      pfam01562
      Location:62 → 154
      Pep_M12B_propep; Reprolysin family propeptide

    5. XM_015110939.1 → XP_014966425.1  disintegrin and metalloproteinase domain-containing protein 15 isoform X1

      UniProtKB/TrEMBL
      H9G1A3
      Related
      ENSMMUP00000030726.4, ENSMMUT00000032840.4
      Conserved Domains (5) summary
      smart00050
      Location:431 → 504
      DISIN; Homologues of snake disintegrins
      smart00608
      Location:509 → 650
      ACR; ADAM Cysteine-Rich Domain
      cd04269
      Location:214 → 412
      ZnMc_adamalysin_II_like; Zinc-dependent metalloprotease; adamalysin_II_like subfamily. Adamalysin II is a snake venom zinc endopeptidase. This subfamily contains other snake venom metalloproteinases, as well as membrane-anchored metalloproteases belonging to the ADAM family. ...
      pfam01421
      Location:214 → 419
      Reprolysin; Reprolysin (M12B) family zinc metalloprotease
      pfam01562
      Location:62 → 154
      Pep_M12B_propep; Reprolysin family propeptide

    6. XM_015110966.2 → XP_014966452.1  disintegrin and metalloproteinase domain-containing protein 15 isoform X5

      UniProtKB/TrEMBL
      H9G1A1
      Conserved Domains (5) summary
      smart00050
      Location:441 → 514
      DISIN; Homologues of snake disintegrins
      smart00608
      Location:519 → 660
      ACR; ADAM Cysteine-Rich Domain
      cd04269
      Location:224 → 422
      ZnMc_adamalysin_II_like; Zinc-dependent metalloprotease; adamalysin_II_like subfamily. Adamalysin II is a snake venom zinc endopeptidase. This subfamily contains other snake venom metalloproteinases, as well as membrane-anchored metalloproteases belonging to the ADAM family. ...
      pfam01421
      Location:224 → 429
      Reprolysin; Reprolysin (M12B) family zinc metalloprotease
      pfam01562
      Location:72 → 164
      Pep_M12B_propep; Reprolysin family propeptide

    7. XM_015110989.2 → XP_014966475.1  disintegrin and metalloproteinase domain-containing protein 15 isoform X7

      UniProtKB/TrEMBL
      F7ED22
      Conserved Domains (5) summary
      smart00050
      Location:441 → 514
      DISIN; Homologues of snake disintegrins
      smart00608
      Location:519 → 660
      ACR; ADAM Cysteine-Rich Domain
      cd04269
      Location:224 → 422
      ZnMc_adamalysin_II_like; Zinc-dependent metalloprotease; adamalysin_II_like subfamily. Adamalysin II is a snake venom zinc endopeptidase. This subfamily contains other snake venom metalloproteinases, as well as membrane-anchored metalloproteases belonging to the ADAM family. ...
      pfam01421
      Location:224 → 429
      Reprolysin; Reprolysin (M12B) family zinc metalloprotease
      pfam01562
      Location:72 → 164
      Pep_M12B_propep; Reprolysin family propeptide

    8. XM_015111011.2 → XP_014966497.1  disintegrin and metalloproteinase domain-containing protein 15 isoform X9

      UniProtKB/TrEMBL
      H9G1A1
      Conserved Domains (5) summary
      smart00050
      Location:441 → 514
      DISIN; Homologues of snake disintegrins
      smart00608
      Location:519 → 660
      ACR; ADAM Cysteine-Rich Domain
      cd04269
      Location:224 → 422
      ZnMc_adamalysin_II_like; Zinc-dependent metalloprotease; adamalysin_II_like subfamily. Adamalysin II is a snake venom zinc endopeptidase. This subfamily contains other snake venom metalloproteinases, as well as membrane-anchored metalloproteases belonging to the ADAM family. ...
      pfam01421
      Location:224 → 429
      Reprolysin; Reprolysin (M12B) family zinc metalloprotease
      pfam01562
      Location:72 → 164
      Pep_M12B_propep; Reprolysin family propeptide

    9. XM_015111004.2 → XP_014966490.1  disintegrin and metalloproteinase domain-containing protein 15 isoform X8

      UniProtKB/TrEMBL
      A0A1D5REF8
      Related
      ENSMMUP00000058701.2, ENSMMUT00000057679.2
      Conserved Domains (5) summary
      smart00050
      Location:441 → 514
      DISIN; Homologues of snake disintegrins
      smart00608
      Location:519 → 660
      ACR; ADAM Cysteine-Rich Domain
      cd04269
      Location:224 → 422
      ZnMc_adamalysin_II_like; Zinc-dependent metalloprotease; adamalysin_II_like subfamily. Adamalysin II is a snake venom zinc endopeptidase. This subfamily contains other snake venom metalloproteinases, as well as membrane-anchored metalloproteases belonging to the ADAM family. ...
      pfam01421
      Location:224 → 429
      Reprolysin; Reprolysin (M12B) family zinc metalloprotease
      pfam01562
      Location:72 → 164
      Pep_M12B_propep; Reprolysin family propeptide

    10. XM_028828448.1 → XP_028684281.1  disintegrin and metalloproteinase domain-containing protein 15 isoform X10

      UniProtKB/TrEMBL
      H9G1A1
      Conserved Domains (4) summary
      smart00050
      Location:441 → 514
      DISIN; Homologues of snake disintegrins
      smart00608
      Location:519 → 660
      ACR; ADAM Cysteine-Rich Domain
      cd04269
      Location:224 → 422
      ZnMc_adamalysin_II_like; Zinc-dependent metalloprotease; adamalysin_II_like subfamily. Adamalysin II is a snake venom zinc endopeptidase. This subfamily contains other snake venom metalloproteinases, as well as membrane-anchored metalloproteases belonging to the ADAM family. ...
      pfam01562
      Location:71 → 164
      Pep_M12B_propep; Reprolysin family propeptide

    11. XM_015111026.2 → XP_014966512.1  disintegrin and metalloproteinase domain-containing protein 15 isoform X11

      Conserved Domains (5) summary
      smart00050
      Location:415 → 488
      DISIN; Homologues of snake disintegrins
      smart00608
      Location:493 → 625
      ACR; ADAM Cysteine-Rich Domain
      cd04269
      Location:198 → 396
      ZnMc_adamalysin_II_like; Zinc-dependent metalloprotease; adamalysin_II_like subfamily. Adamalysin II is a snake venom zinc endopeptidase. This subfamily contains other snake venom metalloproteinases, as well as membrane-anchored metalloproteases belonging to the ADAM family. ...
      pfam01421
      Location:198 → 403
      Reprolysin; Reprolysin (M12B) family zinc metalloprotease
      pfam01562
      Location:72 → 138
      Pep_M12B_propep; Reprolysin family propeptide

    RNA

    1. XR_001438761.2 RNA Sequence

    2. XR_003720138.1 RNA Sequence

    Nucleotide Protein
    Heading Accession and Version

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