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    PFKL phosphofructokinase, liver type [ Macaca mulatta (Rhesus monkey) ]

    Gene ID: 722173, updated on 17-Aug-2024

    Summary

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    Official Symbol
    PFKLprovided by VGNC
    Official Full Name
    phosphofructokinase, liver typeprovided by VGNC
    Primary source
    VGNC:VGNC:81737
    See related
    Ensembl:ENSMMUG00000004173
    Gene type
    protein coding
    RefSeq status
    MODEL
    Organism
    Macaca mulatta
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Cercopithecidae; Cercopithecinae; Macaca
    Orthologs
    human mouse all
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    Genomic context

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    See PFKL in Genome Data Viewer
    Location:
    chromosome: 3
    Exon count:
    23
    Annotation release Status Assembly Chr Location
    103 current Mmul_10 (GCF_003339765.1) 3 NC_041756.1 (2400421..2429229, complement)
    102 previous assembly Mmul_8.0.1 (GCF_000772875.2) 3 NC_027895.1 (2392379..2420646, complement)

    Chromosome 3 - NC_041756.1Genomic Context describing neighboring genes Neighboring gene uncharacterized LOC114676790 Neighboring gene Z6 small nucleolar RNA Neighboring gene transient receptor potential cation channel subfamily M member 2 Neighboring gene uncharacterized LOC106997221 Neighboring gene cilia and flagella associated protein 410 Neighboring gene autoimmune regulator Neighboring gene uncharacterized LOC106997222 Neighboring gene DNA methyltransferase 3 like

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. A new rhesus macaque assembly and annotation for next-generation sequencing analyses. Zimin AV, et al. Biol Direct, 2014 Oct 14. PMID 25319552, Free PMC Article
    2. Manual GO annotation of predictive protein signatures: the InterPro approach to GO curation. Burge S, et al. Database (Oxford), 2012. PMID 22301074, Free PMC Article
    3. TreeGrafter: phylogenetic tree-based annotation of proteins with Gene Ontology terms and other annotations. Tang H, et al. Bioinformatics, 2019 Feb 1. PMID 30032202, Free PMC Article

    GeneRIFs: Gene References Into Functions

    General gene information

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    Homology

    Gene Ontology Provided by RefSeq

    Function Evidence Code Pubs
    enables 6-phosphofructokinase activity IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    enables AMP binding IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    enables ATP binding IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    enables fructose-6-phosphate binding IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    enables identical protein binding IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    enables monosaccharide binding IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    Process Evidence Code Pubs
    involved_in canonical glycolysis IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    involved_in fructose 1,6-bisphosphate metabolic process IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    involved_in fructose 6-phosphate metabolic process IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    Component Evidence Code Pubs
    part_of 6-phosphofructokinase complex IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    located_in cytoplasm IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    located_in membrane IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 

    General protein information

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    Preferred Names
    ATP-dependent 6-phosphofructokinase, liver type
    Names
    6-phosphofructokinase, liver type

    NCBI Reference Sequences (RefSeq)

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    RefSeqs of Annotated Genomes: Macaca mulatta Annotation Release 103 details...Open this link in a new tab

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference Mmul_10 Primary Assembly

    Genomic

    1. NC_041756.1 Reference Mmul_10 Primary Assembly

      Range
      2400421..2429229 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_015132775.2 → XP_014988261.1  ATP-dependent 6-phosphofructokinase, liver type isoform X1

      UniProtKB/TrEMBL
      A0A1D5QYR2, H9FVT0
      Related
      ENSMMUP00000072376.1, ENSMMUT00000107270.1
      Conserved Domains (2) summary
      cd00764
      Location:13 → 773
      Eukaryotic_PFK; Phosphofructokinase, a key regulatory enzyme in glycolysis, catalyzes the phosphorylation of fructose-6-phosphate to fructose-1,6-biphosphate. The members belong to a subfamily of the PFKA family (cd00363) and include eukaryotic ATP-dependent ...
      TIGR02478
      Location:16 → 755
      6PF1K_euk; 6-phosphofructokinase, eukaryotic type

    2. XM_028845274.1 → XP_028701107.1  ATP-dependent 6-phosphofructokinase, liver type isoform X2

      UniProtKB/TrEMBL
      A0A1D5QYR2
      Conserved Domains (1) summary
      cd00764
      Location:21 → 740
      Eukaryotic_PFK; Phosphofructokinase, a key regulatory enzyme in glycolysis, catalyzes the phosphorylation of fructose-6-phosphate to fructose-1,6-biphosphate. The members belong to a subfamily of the PFKA family (cd00363) and include eukaryotic ATP-dependent ...
    Nucleotide Protein
    Heading Accession and Version

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