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    EPS8L3 EPS8 signaling adaptor L3 [ Macaca mulatta (Rhesus monkey) ]

    Gene ID: 700441, updated on 17-Aug-2024

    Summary

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    Official Symbol
    EPS8L3provided by VGNC
    Official Full Name
    EPS8 signaling adaptor L3provided by VGNC
    Primary source
    VGNC:VGNC:72082
    See related
    Ensembl:ENSMMUG00000008030
    Gene type
    protein coding
    RefSeq status
    MODEL
    Organism
    Macaca mulatta
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Cercopithecidae; Cercopithecinae; Macaca
    Orthologs
    human mouse all
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    Genomic context

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    See EPS8L3 in Genome Data Viewer
    Location:
    chromosome: 1
    Exon count:
    19
    Annotation release Status Assembly Chr Location
    103 current Mmul_10 (GCF_003339765.1) 1 NC_041754.1 (114372188..114386089)
    102 previous assembly Mmul_8.0.1 (GCF_000772875.2) 1 NC_027893.1 (110768824..110780757, complement)

    Chromosome 1 - NC_041754.1Genomic Context describing neighboring genes Neighboring gene uncharacterized LOC114671281 Neighboring gene NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 5 pseudogene Neighboring gene glutathione S-transferase mu 3 Neighboring gene glutathione S-transferase mu 5

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. A new rhesus macaque assembly and annotation for next-generation sequencing analyses. Zimin AV, et al. Biol Direct, 2014 Oct 14. PMID 25319552, Free PMC Article
    2. TreeGrafter: phylogenetic tree-based annotation of proteins with Gene Ontology terms and other annotations. Tang H, et al. Bioinformatics, 2019 Feb 1. PMID 30032202, Free PMC Article

    GeneRIFs: Gene References Into Functions

    General gene information

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    Markers

    Homology

    Gene Ontology Provided by RefSeq

    Function Evidence Code Pubs
    enables actin binding IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    Process Evidence Code Pubs
    involved_in Rho protein signal transduction IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    involved_in positive regulation of ruffle assembly IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    involved_in regulation of Rho protein signal transduction IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    Component Evidence Code Pubs
    located_in plasma membrane IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    located_in ruffle membrane IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    located_in vesicle IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 

    General protein information

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    Preferred Names
    epidermal growth factor receptor kinase substrate 8-like protein 3
    Names
    EPS8 like 3

    NCBI Reference Sequences (RefSeq)

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    RefSeqs of Annotated Genomes: Macaca mulatta Annotation Release 103 details...Open this link in a new tab

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference Mmul_10 Primary Assembly

    Genomic

    1. NC_041754.1 Reference Mmul_10 Primary Assembly

      Range
      114372188..114386089
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_028830591.1 → XP_028686424.1  epidermal growth factor receptor kinase substrate 8-like protein 3 isoform X1

      UniProtKB/TrEMBL
      F7H5A6, G7MIE9
      Conserved Domains (3) summary
      cd11764
      Location:457 → 509
      SH3_Eps8; Src Homology 3 domain of Epidermal growth factor receptor kinase substrate 8 and similar proteins
      cd01210
      Location:25 → 154
      PTB_EPS8; Epidermal growth factor receptor kinase substrate (EPS8)-like Phosphotyrosine-binding (PTB) domain
      cl15755
      Location:526 → 591
      SAM_superfamily; SAM (Sterile alpha motif )

    2. XM_015147874.2 → XP_015003360.1  epidermal growth factor receptor kinase substrate 8-like protein 3 isoform X2

      UniProtKB/TrEMBL
      G7MIE9
      Conserved Domains (3) summary
      cd11764
      Location:456 → 508
      SH3_Eps8; Src Homology 3 domain of Epidermal growth factor receptor kinase substrate 8 and similar proteins
      cd01210
      Location:25 → 154
      PTB_EPS8; Epidermal growth factor receptor kinase substrate (EPS8)-like Phosphotyrosine-binding (PTB) domain
      cl15755
      Location:525 → 590
      SAM_superfamily; SAM (Sterile alpha motif )

    3. XM_028830597.1 → XP_028686430.1  epidermal growth factor receptor kinase substrate 8-like protein 3 isoform X1

      UniProtKB/TrEMBL
      F7H5A6, G7MIE9
      Related
      ENSMMUP00000010530.2, ENSMMUT00000011234.4
      Conserved Domains (3) summary
      cd11764
      Location:457 → 509
      SH3_Eps8; Src Homology 3 domain of Epidermal growth factor receptor kinase substrate 8 and similar proteins
      cd01210
      Location:25 → 154
      PTB_EPS8; Epidermal growth factor receptor kinase substrate (EPS8)-like Phosphotyrosine-binding (PTB) domain
      cl15755
      Location:526 → 591
      SAM_superfamily; SAM (Sterile alpha motif )
    Nucleotide Protein
    Heading Accession and Version

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