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    Vmn2r121 vomeronasal 2, receptor 121 [ Mus musculus (house mouse) ]

    Gene ID: 100038941, updated on 27-Nov-2024

    Summary

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    Official Symbol
    Vmn2r121provided by MGI
    Official Full Name
    vomeronasal 2, receptor 121provided by MGI
    Primary source
    MGI:MGI:3643045
    See related
    Ensembl:ENSMUSG00000072049 AllianceGenome:MGI:3643045
    Gene type
    protein coding
    RefSeq status
    PROVISIONAL
    Organism
    Mus musculus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
    Also known as
    EG625699
    Summary
    Predicted to enable G protein-coupled receptor activity. Predicted to be active in plasma membrane. [provided by Alliance of Genome Resources, Nov 2024]
    Expression
    Low expression observed in reference dataset See more
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    Genomic context

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    See Vmn2r121 in Genome Data Viewer
    Location:
    X E3; X 49.81 cM
    Exon count:
    6
    Annotation release Status Assembly Chr Location
    RS_2024_02 current GRCm39 (GCF_000001635.27) X NC_000086.8 (123037036..123045607, complement)
    108.20200622 previous assembly GRCm38.p6 (GCF_000001635.26) X NC_000086.7 (124127339..124135910, complement)

    Chromosome X - NC_000086.8Genomic Context describing neighboring genes Neighboring gene ribosomal protein S12, pseudogene 20 Neighboring gene claudin 34C5 Neighboring gene STARR-seq mESC enhancer starr_47885 Neighboring gene STARR-seq mESC enhancer starr_47886 Neighboring gene STARR-seq mESC enhancer starr_47887 Neighboring gene ribosomal protein S12, pseudogene 6 Neighboring gene ribosomal protein S12, pseudogene 11

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Expression

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    • Project title: Mouse ENCODE transcriptome data
    • Description: RNA profiling data sets generated by the Mouse ENCODE project.
    • BioProject: PRJNA66167
    • Publication: PMID 25409824
    • Analysis date: n/a

    Bibliography

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    Related articles in PubMed

    1. A multigene family encoding a diverse array of putative pheromone receptors in mammals. Matsunami H, et al. Cell, 1997 Aug 22. PMID 9288756
    2. Diversity within olfactory sensory derivatives revealed by the contribution of Dbx1 lineages. Causeret F, et al. J Comp Neurol, 2023 Aug. PMID 37125418
    3. V2R gene families degenerated in primates, dog and cow, but expanded in opossum. Young JM, et al. Trends Genet, 2007 May. PMID 17382427
    4. Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. Strausberg RL, et al. Proc Natl Acad Sci U S A, 2002 Dec 24. PMID 12477932, Free PMC Article
    5. Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Gaudet P, et al. Brief Bioinform, 2011 Sep. PMID 21873635, Free PMC Article

    GeneRIFs: Gene References Into Functions

    General gene information

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    Homology

    Gene Ontology Provided by MGI

    Function Evidence Code Pubs
    enables G protein-coupled receptor activity IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    Component Evidence Code Pubs
    is_active_in plasma membrane IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  

    General protein information

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    Preferred Names
    vomeronasal 2, receptor 121
    Names
    vomeronasal receptor Vmn2r121

    NCBI Reference Sequences (RefSeq)

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    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_001100616.1 → NP_001094086.1  vomeronasal 2, receptor 121 precursor

      Status: PROVISIONAL

      Source sequence(s)
      BX005197
      Consensus CDS
      CCDS53179.1
      UniProtKB/TrEMBL
      A0A3Q4EIC8, A2BE32
      Related
      ENSMUSP00000092067.4, ENSMUST00000094491.5
      Conserved Domains (3) summary
      cd06365
      Location:40 → 499
      PBP1_Pheromone_receptor; Ligand-binding domain of the V2R phermone receptor, a member of the family C receptors within the G-protein coupled receptor superfamily
      pfam00003
      Location:594 → 828
      7tm_3; 7 transmembrane sweet-taste receptor of 3 GCPR
      pfam07562
      Location:507 → 559
      NCD3G; Nine Cysteines Domain of family 3 GPCR

    RefSeqs of Annotated Genomes: GCF_000001635.27-RS_2024_02

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCm39 C57BL/6J

    Genomic

    1. NC_000086.8 Reference GRCm39 C57BL/6J

      Range
      123037036..123045607 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_036161743.1 → XP_036017636.1  vomeronasal 2, receptor 121 isoform X1

      UniProtKB/TrEMBL
      A0A3Q4EIC8
      Conserved Domains (3) summary
      cd15283
      Location:579 → 829
      7tmC_V2R_pheromone; vomeronasal type-2 pheromone receptors, member of the class C family of seven-transmembrane G protein-coupled receptors
      cd06365
      Location:46 → 499
      PBP1_pheromone_receptor; Ligand-binding domain of the V2R pheromone receptor, a member of the family C receptors within the G-protein coupled receptor superfamily
      pfam07562
      Location:506 → 559
      NCD3G; Nine Cysteines Domain of family 3 GPCR

    2. XM_017318330.1 → XP_017173819.1  vomeronasal 2, receptor 121 isoform X3

      Conserved Domains (1) summary
      cl10011
      Location:46 → 431
      Periplasmic_Binding_Protein_type1; Type 1 periplasmic binding fold superfamily

    3. XM_017318329.1 → XP_017173818.1  vomeronasal 2, receptor 121 isoform X2

      Conserved Domains (1) summary
      cl10011
      Location:46 → 430
      Periplasmic_Binding_Protein_type1; Type 1 periplasmic binding fold superfamily
    Nucleotide Protein Strain
    Heading Accession and Version

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