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    Cldn34b4 claudin 34B4 [ Mus musculus (house mouse) ]

    Gene ID: 619294, updated on 9-Dec-2024

    Summary

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    Official Symbol
    Cldn34b4provided by MGI
    Official Full Name
    claudin 34B4provided by MGI
    Primary source
    MGI:MGI:3588232
    See related
    Ensembl:ENSMUSG00000073085 AllianceGenome:MGI:3588232
    Gene type
    protein coding
    RefSeq status
    VALIDATED
    Organism
    Mus musculus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
    Also known as
    4930428D18Rik
    Summary
    Predicted to be involved in bicellular tight junction assembly and cell adhesion. Predicted to be active in bicellular tight junction and plasma membrane. Orthologous to human CLDN34 (claudin 34). [provided by Alliance of Genome Resources, Dec 2024]
    Expression
    Restricted expression toward testis adult (RPKM 5.7) See more
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    Genomic context

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    See Cldn34b4 in Genome Data Viewer
    Location:
    X A7.3; X 38.3 cM
    Exon count:
    4
    Annotation release Status Assembly Chr Location
    RS_2024_02 current GRCm39 (GCF_000001635.27) X NC_000086.8 (75428929..75441585)
    108.20200622 previous assembly GRCm38.p6 (GCF_000001635.26) X NC_000086.7 (76385323..76397979)

    Chromosome X - NC_000086.8Genomic Context describing neighboring genes Neighboring gene leucine rich repeat containing 58 pseudogene Neighboring gene MAGE family member A7, pseudogene Neighboring gene STARR-seq mESC enhancer starr_47398 Neighboring gene STARR-seq mESC enhancer starr_47399 Neighboring gene STARR-seq mESC enhancer starr_47400 Neighboring gene STARR-seq mESC enhancer starr_47401 Neighboring gene predicted pseudogene 5793 Neighboring gene claudin 34D

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Expression

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    • Project title: Mouse ENCODE transcriptome data
    • Description: RNA profiling data sets generated by the Mouse ENCODE project.
    • BioProject: PRJNA66167
    • Publication: PMID 25409824
    • Analysis date: n/a

    Bibliography

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    Related articles in PubMed

    1. Antisense transcription in the mammalian transcriptome. Katayama S, et al. Science, 2005 Sep 2. PMID 16141073
    2. High-efficiency full-length cDNA cloning. Carninci P, et al. Methods Enzymol, 1999. PMID 10349636
    3. RIKEN integrated sequence analysis (RISA) system--384-format sequencing pipeline with 384 multicapillary sequencer. Shibata K, et al. Genome Res, 2000 Nov. PMID 11076861, Free PMC Article
    4. Normalization and subtraction of cap-trapper-selected cDNAs to prepare full-length cDNA libraries for rapid discovery of new genes. Carninci P, et al. Genome Res, 2000 Oct. PMID 11042159, Free PMC Article
    5. Functional annotation of a full-length mouse cDNA collection. Kawai J, et al. Nature, 2001 Feb 8. PMID 11217851

    See all (9) citations in PubMed

    GeneRIFs: Gene References Into Functions

    Variation

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    Alleles

    Alleles of this type are documented at Mouse Genome Informatics  (MGI)
    • Endonuclease-mediated (1) 

    General gene information

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    Homology

    Gene Ontology Provided by MGI

    Function Evidence Code Pubs
    enables molecular_function ND
    No biological Data available
    more info
    		  
    Process Evidence Code Pubs
    involved_in bicellular tight junction assembly IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    involved_in cell adhesion IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    Component Evidence Code Pubs
    is_active_in bicellular tight junction IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    is_active_in plasma membrane IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  

    General protein information

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    Preferred Names
    claudin 34B4

    NCBI Reference Sequences (RefSeq)

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    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_001033799.2 → NP_001028971.1  claudin 34B4

      See identical proteins and their annotated locations for NP_001028971.1

      Status: VALIDATED

      Source sequence(s)
      AK132827
      Consensus CDS
      CCDS53116.1
      UniProtKB/TrEMBL
      Q3V0X2
      Related
      ENSMUSP00000098964.2, ENSMUST00000101419.2
      Conserved Domains (1) summary
      cl21598
      Location:19 → 198
      PMP22_Claudin; PMP-22/EMP/MP20/Claudin family

    2. NM_001356396.1 → NP_001343325.1  claudin 34B4

      Status: VALIDATED

      Source sequence(s)
      AL672017, BC147626
      Consensus CDS
      CCDS53116.1
      UniProtKB/TrEMBL
      Q3V0X2
      Conserved Domains (1) summary
      cl21598
      Location:19 → 198
      PMP22_Claudin; PMP-22/EMP/MP20/Claudin family

    RefSeqs of Annotated Genomes: GCF_000001635.27-RS_2024_02

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCm39 C57BL/6J

    Genomic

    1. NC_000086.8 Reference GRCm39 C57BL/6J

      Range
      75428929..75441585
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_006528213.2 → XP_006528276.1  claudin 34B4 isoform X1

      See identical proteins and their annotated locations for XP_006528276.1

      UniProtKB/TrEMBL
      Q3V0X2
      Related
      ENSMUSP00000159557.1, ENSMUST00000249074.1
      Conserved Domains (1) summary
      cl21598
      Location:19 → 198
      PMP22_Claudin; PMP-22/EMP/MP20/Claudin family
    Nucleotide Protein Strain
    Heading Accession and Version

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