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    Phyhip phytanoyl-CoA hydroxylase interacting protein [ Mus musculus (house mouse) ]

    Gene ID: 105653, updated on 9-Dec-2024

    Summary

    Official Symbol
    Phyhipprovided by MGI
    Official Full Name
    phytanoyl-CoA hydroxylase interacting proteinprovided by MGI
    Primary source
    MGI:MGI:1860417
    See related
    Ensembl:ENSMUSG00000003469 AllianceGenome:MGI:1860417
    Gene type
    protein coding
    RefSeq status
    PROVISIONAL
    Organism
    Mus musculus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
    Also known as
    Lnap1ip; PAHX-AP1; PAHX-AP#1; C630010D02Rik
    Summary
    Predicted to enable protein tyrosine kinase binding activity. Predicted to be involved in protein localization. Predicted to be active in cytoplasm. Is expressed in several structures, including central nervous system; hemolymphoid system gland; musculoskeletal system; nose; and skin. Orthologous to human PHYHIP (phytanoyl-CoA 2-hydroxylase interacting protein). [provided by Alliance of Genome Resources, Dec 2024]
    Expression
    Biased expression in cerebellum adult (RPKM 89.9), cortex adult (RPKM 83.2) and 4 other tissues See more
    Orthologs
    NEW
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    Try the new Transcript table

    Genomic context

    See Phyhip in Genome Data Viewer
    Location:
    14 D2; 14 36.32 cM
    Exon count:
    7
    Annotation release Status Assembly Chr Location
    RS_2024_02 current GRCm39 (GCF_000001635.27) 14 NC_000080.7 (70694957..70706266)
    108.20200622 previous assembly GRCm38.p6 (GCF_000001635.26) 14 NC_000080.6 (70457517..70468826)

    Chromosome 14 - NC_000080.7Genomic Context describing neighboring genes Neighboring gene STARR-positive B cell enhancer mm9_chr14:70842927-70843227 Neighboring gene polymerase (RNA) III (DNA directed) polypeptide D Neighboring gene microRNA 320 Neighboring gene STARR-positive B cell enhancer ABC_E7332 Neighboring gene bone morphogenetic protein 1 Neighboring gene predicted gene, 52136 Neighboring gene CapStarr-seq enhancer MGSCv37_chr14:70920317-70920426 Neighboring gene surfactant associated protein C

    Genomic regions, transcripts, and products

    Expression

    • Project title: Mouse ENCODE transcriptome data
    • Description: RNA profiling data sets generated by the Mouse ENCODE project.
    • BioProject: PRJNA66167
    • Publication: PMID 25409824
    • Analysis date: n/a

    Variation

    Alleles

    Alleles of this type are documented at Mouse Genome Informatics  (MGI)
    • Endonuclease-mediated (1) 
    • Targeted (1) 

    Interactions

    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

    Markers

    Clone Names

    • MGC40960

    Gene Ontology Provided by MGI

    Function Evidence Code Pubs
    enables protein binding IPI
    Inferred from Physical Interaction
    more info
    PubMed 
    enables protein tyrosine kinase binding IEA
    Inferred from Electronic Annotation
    more info
     
    enables protein tyrosine kinase binding ISO
    Inferred from Sequence Orthology
    more info
     
    Process Evidence Code Pubs
    involved_in protein localization ISO
    Inferred from Sequence Orthology
    more info
     
    involved_in protein localization ISS
    Inferred from Sequence or Structural Similarity
    more info
     
    Component Evidence Code Pubs
    is_active_in cytoplasm IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    located_in cytoplasm ISO
    Inferred from Sequence Orthology
    more info
     
    located_in cytoplasm ISS
    Inferred from Sequence or Structural Similarity
    more info
     

    General protein information

    Preferred Names
    phytanoyl-CoA hydroxylase-interacting protein
    Names
    PAHXAP1
    lupus nephritis-associated peptide 1 interacting protein
    phytanoyl-CoA hydroxylase-associated protein 1

    NCBI Reference Sequences (RefSeq)

    NEW Try the new Transcript table

    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_145981.3NP_666093.1  phytanoyl-CoA hydroxylase-interacting protein

      See identical proteins and their annotated locations for NP_666093.1

      Status: PROVISIONAL

      Source sequence(s)
      AK049900
      Consensus CDS
      CCDS36971.1
      UniProtKB/Swiss-Prot
      Q8K0S0
      UniProtKB/TrEMBL
      B9EIC7
      Related
      ENSMUSP00000003561.4, ENSMUST00000003561.10
      Conserved Domains (1) summary
      cd00063
      Location:5112
      FN3; Fibronectin type 3 domain; One of three types of internal repeats found in the plasma protein fibronectin. Its tenth fibronectin type III repeat contains an RGD cell recognition sequence in a flexible loop between 2 strands. Approximately 2% of all ...

    RefSeqs of Annotated Genomes: GCF_000001635.27-RS_2024_02

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCm39 C57BL/6J

    Genomic

    1. NC_000080.7 Reference GRCm39 C57BL/6J

      Range
      70694957..70706266
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_006518379.5XP_006518442.1  phytanoyl-CoA hydroxylase-interacting protein isoform X1

      See identical proteins and their annotated locations for XP_006518442.1

      UniProtKB/Swiss-Prot
      Q8K0S0
      UniProtKB/TrEMBL
      B9EIC7
      Conserved Domains (1) summary
      cd00063
      Location:5112
      FN3; Fibronectin type 3 domain; One of three types of internal repeats found in the plasma protein fibronectin. Its tenth fibronectin type III repeat contains an RGD cell recognition sequence in a flexible loop between 2 strands. Approximately 2% of all ...
    2. XM_006518380.4XP_006518443.1  phytanoyl-CoA hydroxylase-interacting protein isoform X1

      See identical proteins and their annotated locations for XP_006518443.1

      UniProtKB/Swiss-Prot
      Q8K0S0
      UniProtKB/TrEMBL
      B9EIC7
      Conserved Domains (1) summary
      cd00063
      Location:5112
      FN3; Fibronectin type 3 domain; One of three types of internal repeats found in the plasma protein fibronectin. Its tenth fibronectin type III repeat contains an RGD cell recognition sequence in a flexible loop between 2 strands. Approximately 2% of all ...