Mei1 meiotic double-stranded break formation protein 1 [Rattus norvegicus (Norway rat)] - Gene

Summary

Official Symbol: Mei1provided by RGD
Official Full Name: meiotic double-stranded break formation protein 1provided by RGD
Primary source: RGD:1307210
See related: EnsemblRapid:ENSRNOG00000007003 AllianceGenome:RGD:1307210
Gene type: protein coding
RefSeq status: PROVISIONAL
Organism: Rattus norvegicus
Lineage: Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Rattus
Summary: Predicted to be involved in meiosis I. Predicted to act upstream of or within germ cell development; meiotic nuclear division; and meiotic spindle organization. Human ortholog(s) of this gene implicated in gestational trophoblastic neoplasm. Orthologous to human MEI1 (meiotic double-stranded break formation protein 1). [provided by Alliance of Genome Resources, Dec 2024]
Expression: Biased expression in Testes (RPKM 10.8), Brain (RPKM 3.8) and 3 other tissues See more
Orthologs: human mouse all
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Genomic context

Location:: 7q34

Exon count:: 32

Annotation release	Status	Assembly	Chr	Location
RS_2024_02	current	GRCr8 (GCF_036323735.1)	7	NC_086025.1 (115470256..115523618)
RS_2023_06	previous assembly	mRatBN7.2 (GCF_015227675.2)	7	NC_051342.1 (113590142..113643513)
106	previous assembly	Rnor_6.0 (GCF_000001895.5)	7	NC_005106.4 (123308041..123361391)

Chromosome 7 - NC_086025.1 Genomic Context describing neighboring genes

Genomic regions, transcripts, and products

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Genomic Sequence:

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Expression

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See details

Project title: A rat RNA-Seq transcriptomic BodyMap across 11 organs and 4 developmental stages
Description: 320 RNA samples isolated from 11 organs (adrenal gland, brain, heart, kidney, liver, lung, muscle, spleen, thymus, and testes or uterus) from both sexes of Fischer 344 rats across four developmental stages (2-, 6-, 21-, and 104-weeks-old)
BioProject: PRJNA238328
Publication: PMID 24510058
Analysis date: Mon Jun 6 17:44:12 2016

Bibliography

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GeneRIFs: Gene References Into Functions

What's a GeneRIF?

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General gene information

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Gene Ontology Provided by RGD

Process	Evidence Code	Pubs
acts_upstream_of_or_within gamete generation	ISO Inferred from Sequence Orthology more info
acts_upstream_of_or_within male meiosis I	ISO Inferred from Sequence Orthology more info
involved_in meiosis I	IBA Inferred from Biological aspect of Ancestor more info
acts_upstream_of_or_within meiotic cell cycle	ISO Inferred from Sequence Orthology more info
acts_upstream_of_or_within meiotic spindle organization	ISO Inferred from Sequence Orthology more info
acts_upstream_of_or_within meiotic telomere clustering	ISO Inferred from Sequence Orthology more info
acts_upstream_of_or_within oogenesis	ISO Inferred from Sequence Orthology more info
acts_upstream_of_or_within polar body extrusion after meiotic divisions	ISO Inferred from Sequence Orthology more info
acts_upstream_of_or_within spermatid development	ISO Inferred from Sequence Orthology more info
acts_upstream_of_or_within spermatogenesis	ISO Inferred from Sequence Orthology more info

General protein information

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Preferred Names: meiosis inhibitor protein 1

Names: meiosis defective 1; meiosis inhibitor 1

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.