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    USH1C USH1 protein network component harmonin [ Bos taurus (domestic cattle) ]

    Gene ID: 530709, updated on 27-Dec-2024

    Summary

    Official Symbol
    USH1Cprovided by VGNC
    Official Full Name
    USH1 protein network component harmoninprovided by VGNC
    Primary source
    VGNC:VGNC:36704
    See related
    BGD:BT26172; Ensembl:ENSBTAG00000000986
    Gene type
    protein coding
    RefSeq status
    PROVISIONAL
    Organism
    Bos taurus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Laurasiatheria; Artiodactyla; Ruminantia; Pecora; Bovidae; Bovinae; Bos
    Orthologs
    NEW
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    Genomic context

    See USH1C in Genome Data Viewer
    Location:
    chromosome: 15
    Exon count:
    26
    Annotation release Status Assembly Chr Location
    RS_2024_12 current ARS-UCD2.0 (GCF_002263795.3) 15 NC_037342.1 (34963006..35011742)

    Chromosome 15 - NC_037342.1Genomic Context describing neighboring genes Neighboring gene myogenic differentiation 1 Neighboring gene otogelin Neighboring gene ATP binding cassette subfamily C member 8 Neighboring gene potassium inwardly rectifying channel subfamily J member 11

    Genomic regions, transcripts, and products

    Genomic Sequence:
    NC_037342.1 Chromosome 15 Reference ARS-UCD2.0 Primary Assembly

    Expression

    • Project title: Dominette sequence data
    • BioProject: PRJNA294306
    • Analysis date: Tue Dec 17 08:57:05 2024

    General gene information

    Clone Names

    • MGC127911

    Gene Ontology Provided by RefSeq

    Function Evidence Code Pubs
    enables protein binding IEA
    Inferred from Electronic Annotation
    more info
    PubMed 
    Process Evidence Code Pubs
    involved_in inner ear auditory receptor cell differentiation IEA
    Inferred from Electronic Annotation
    more info
    PubMed 
    involved_in inner ear morphogenesis IEA
    Inferred from Electronic Annotation
    more info
    PubMed 
    involved_in inner ear receptor cell stereocilium organization IEA
    Inferred from Electronic Annotation
    more info
    PubMed 
    involved_in retinal cone cell development IEA
    Inferred from Electronic Annotation
    more info
    PubMed 
    involved_in sensory perception of sound IEA
    Inferred from Electronic Annotation
    more info
    PubMed 
    Component Evidence Code Pubs
    located_in cilium IEA
    Inferred from Electronic Annotation
    more info
    PubMed 
    located_in photoreceptor inner segment IEA
    Inferred from Electronic Annotation
    more info
    PubMed 
    located_in plasma membrane IEA
    Inferred from Electronic Annotation
    more info
    PubMed 
    part_of stereocilia ankle link complex IEA
    Inferred from Electronic Annotation
    more info
    PubMed 
    located_in stereocilium tip IEA
    Inferred from Electronic Annotation
    more info
    PubMed 

    General protein information

    Preferred Names
    harmonin
    Names
    Usher syndrome 1C (autosomal recessive, severe)
    usher syndrome type-1C protein homolog

    NCBI Reference Sequences (RefSeq)

    NEW Try the new Transcript table

    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_001035382.2NP_001030459.1  harmonin

      See identical proteins and their annotated locations for NP_001030459.1

      Status: PROVISIONAL

      Source sequence(s)
      BC105153
      UniProtKB/Swiss-Prot
      Q3MHQ0
      UniProtKB/TrEMBL
      F1MIQ5
      Related
      ENSBTAP00000001304.5, ENSBTAT00000001304.6
      Conserved Domains (3) summary
      cd00992
      Location:85165
      PDZ_signaling; PDZ domain found in a variety of Eumetazoan signaling molecules, often in tandem arrangements. May be responsible for specific protein-protein interactions, as most PDZ domains bind C-terminal polypeptides, and binding to internal (non-C-terminal) ...
      cd07353
      Location:280
      harmonin_N; N-terminal protein-binding module of harmonin
      pfam03879
      Location:316358
      Cgr1; Cgr1 family

    RefSeqs of Annotated Genomes: GCF_002263795.3-RS_2024_12

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference ARS-UCD2.0 Primary Assembly

    Genomic

    1. NC_037342.1 Reference ARS-UCD2.0 Primary Assembly

      Range
      34963006..35011742
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_010812478.4XP_010810780.2  harmonin isoform X1

      Conserved Domains (3) summary
      cd00992
      Location:85165
      PDZ_signaling; PDZ domain found in a variety of Eumetazoan signaling molecules, often in tandem arrangements. May be responsible for specific protein-protein interactions, as most PDZ domains bind C-terminal polypeptides, and binding to internal (non-C-terminal) ...
      cd07353
      Location:280
      harmonin_N; N-terminal protein-binding module of harmonin
      cl25545
      Location:301353
      V-ATPase_G_2; Vacuolar (H+)-ATPase G subunit
    2. XM_059874776.1XP_059730759.1  harmonin isoform X2

    3. XM_010812479.4XP_010810781.2  harmonin isoform X3

      Conserved Domains (3) summary
      cd00992
      Location:85165
      PDZ_signaling; PDZ domain found in a variety of Eumetazoan signaling molecules, often in tandem arrangements. May be responsible for specific protein-protein interactions, as most PDZ domains bind C-terminal polypeptides, and binding to internal (non-C-terminal) ...
      cd07353
      Location:280
      harmonin_N; N-terminal protein-binding module of harmonin
      cl25545
      Location:301353
      V-ATPase_G_2; Vacuolar (H+)-ATPase G subunit