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    REXO1 RNA exonuclease 1 homolog [ Bos taurus (domestic cattle) ]

    Gene ID: 512048, updated on 27-Dec-2024

    Summary

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    Official Symbol
    REXO1provided by VGNC
    Official Full Name
    RNA exonuclease 1 homologprovided by VGNC
    Primary source
    VGNC:VGNC:55305
    See related
    BGD:BT17090; Ensembl:ENSBTAG00000020232
    Gene type
    protein coding
    RefSeq status
    VALIDATED
    Organism
    Bos taurus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Laurasiatheria; Artiodactyla; Ruminantia; Pecora; Bovidae; Bovinae; Bos
    Orthologs
    human mouse all
    NEW
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    Genomic context

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    See REXO1 in Genome Data Viewer
    Location:
    chromosome: 7
    Exon count:
    16
    Annotation release Status Assembly Chr Location
    RS_2024_12 current ARS-UCD2.0 (GCF_002263795.3) 7 NC_037334.1 (44149350..44168830, complement)

    Chromosome 7 - NC_037334.1Genomic Context describing neighboring genes Neighboring gene ATPase phospholipid transporting 8B3 Neighboring gene uncharacterized LOC132345744 Neighboring gene uncharacterized LOC112447414 Neighboring gene KLF transcription factor 16 Neighboring gene abhydrolase domain containing 17A, depalmitoylase

    Genomic regions, transcripts, and products

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    Genomic Sequence:
    NC_037334.1 Chromosome 7 Reference ARS-UCD2.0 Primary Assembly

    Go to nucleotide: Graphics FASTA GenBank

    Expression

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    • Project title: Dominette sequence data
    • BioProject: PRJNA294306
    • Analysis date: Tue Dec 17 08:57:05 2024

    Bibliography

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    Related articles in PubMed

    1. Methylation patterns in 5' terminal regions of pluripotency-related genes in mature bovine gametes. Lan J, et al. Zygote, 2011 May. PMID 20604984
    2. A whole-genome assembly of the domestic cow, Bos taurus. Zimin AV, et al. Genome Biol, 2009. PMID 19393038, Free PMC Article
    3. Manual GO annotation of predictive protein signatures: the InterPro approach to GO curation. Burge S, et al. Database (Oxford), 2012. PMID 22301074, Free PMC Article
    4. TreeGrafter: phylogenetic tree-based annotation of proteins with Gene Ontology terms and other annotations. Tang H, et al. Bioinformatics, 2019 Feb 1. PMID 30032202, Free PMC Article

    GeneRIFs: Gene References Into Functions

    What's a GeneRIF?
    1. Rex1 showed a relatively high methylation level in sperm than in oocytes, although no significant differences were found
      Title: Methylation patterns in 5' terminal regions of pluripotency-related genes in mature bovine gametes.
    Submit: New GeneRIF Correction

    General gene information

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    Homology

    Gene Ontology Provided by RefSeq

    Function Evidence Code Pubs
    enables exonuclease activity IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    enables nucleic acid binding IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    Component Evidence Code Pubs
    located_in nucleus IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 

    General protein information

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    Preferred Names
    RNA exonuclease 1 homolog

    NCBI Reference Sequences (RefSeq)

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    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_001192308.2 → NP_001179237.2  RNA exonuclease 1 homolog

      Status: VALIDATED

      Source sequence(s)
      NKLS02000007
      UniProtKB/TrEMBL
      A0A3Q1ME34
      Related
      ENSBTAP00000067121.2, ENSBTAT00000086146.2
      Conserved Domains (4) summary
      cd06145
      Location:1047 → 1195
      REX1_like; DEDDh 3'-5' exonuclease domain of RNA exonuclease 1, -3 and similar eukaryotic proteins
      PHA03307
      Location:386 → 538
      PHA03307; transcriptional regulator ICP4; Provisional
      PRK07003
      Location:241 → 458
      PRK07003; DNA polymerase III subunit gamma/tau
      pfam15870
      Location:788 → 948
      EloA-BP1; ElonginA binding-protein 1

    RefSeqs of Annotated Genomes: GCF_002263795.3-RS_2024_12

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference ARS-UCD2.0 Primary Assembly

    Genomic

    1. NC_037334.1 Reference ARS-UCD2.0 Primary Assembly

      Range
      44149350..44168830 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_059888093.1 → XP_059744076.1  RNA exonuclease 1 homolog isoform X1

    Nucleotide Protein Strain
    Heading Accession and Version

    Gene LinkOut

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    Molecular Biology Databases
    Research Materials