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    RAP1GAP RAP1 GTPase activating protein [ Bos taurus (domestic cattle) ]

    Gene ID: 532839, updated on 29-Jan-2025

    Summary

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    Official Symbol
    RAP1GAPprovided by VGNC
    Official Full Name
    RAP1 GTPase activating proteinprovided by VGNC
    Primary source
    VGNC:VGNC:33716
    See related
    Ensembl:ENSBTAG00000008952
    Gene type
    protein coding
    RefSeq status
    PROVISIONAL
    Organism
    Bos taurus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Laurasiatheria; Artiodactyla; Ruminantia; Pecora; Bovidae; Bovinae; Bos
    Orthologs
    human mouse all
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    Genomic context

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    See RAP1GAP in Genome Data Viewer
    Location:
    chromosome: 2
    Exon count:
    28
    Annotation release Status Assembly Chr Location
    RS_2024_12 current ARS-UCD2.0 (GCF_002263795.3) 2 NC_037329.1 (131095754..131165879)

    Chromosome 2 - NC_037329.1Genomic Context describing neighboring genes Neighboring gene heparan sulfate proteoglycan 2 Neighboring gene low density lipoprotein receptor class A domain containing 2 Neighboring gene small nucleolar RNA U13 Neighboring gene ubiquitin specific peptidase 48 Neighboring gene U6 spliceosomal RNA Neighboring gene alkaline phosphatase, biomineralization associated Neighboring gene large ribosomal subunit protein eL39-like

    Genomic regions, transcripts, and products

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    Genomic Sequence:
    NC_037329.1 Chromosome 2 Reference ARS-UCD2.0 Primary Assembly

    Go to nucleotide: Graphics FASTA GenBank

    Expression

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    • Project title: Dominette sequence data
    • BioProject: PRJNA294306
    • Analysis date: Tue Dec 17 08:57:05 2024

    Bibliography

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    Related articles in PubMed

    1. A whole-genome assembly of the domestic cow, Bos taurus. Zimin AV, et al. Genome Biol, 2009. PMID 19393038, Free PMC Article
    2. Manual GO annotation of predictive protein signatures: the InterPro approach to GO curation. Burge S, et al. Database (Oxford), 2012. PMID 22301074, Free PMC Article
    3. TreeGrafter: phylogenetic tree-based annotation of proteins with Gene Ontology terms and other annotations. Tang H, et al. Bioinformatics, 2019 Feb 1. PMID 30032202, Free PMC Article

    GeneRIFs: Gene References Into Functions

    Pathways from PubChem

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    General gene information

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    Homology

    Clone Names

    • MGC139675

    Gene Ontology Provided by RefSeq

    Function Evidence Code Pubs
    enables GTPase activator activity IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    Process Evidence Code Pubs
    involved_in activation of GTPase activity IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    involved_in regulation of small GTPase mediated signal transduction IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    Component Evidence Code Pubs
    located_in cytoplasm IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    located_in membrane IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 

    General protein information

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    Preferred Names
    rap1 GTPase-activating protein 1

    NCBI Reference Sequences (RefSeq)

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    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_001076888.1 → NP_001070356.1  rap1 GTPase-activating protein 1

      Status: PROVISIONAL

      Source sequence(s)
      BC123395
      UniProtKB/TrEMBL
      A0A3S5ZPH9, F1MVZ0, Q08E64
      Related
      ENSBTAP00070013765.1, ENSBTAT00070023340.1
      Conserved Domains (2) summary
      pfam02145
      Location:211 → 390
      Rap_GAP; Rap/ran-GAP
      pfam02188
      Location:1 → 17
      GoLoco; GoLoco motif

    RefSeqs of Annotated Genomes: GCF_002263795.3-RS_2024_12

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference ARS-UCD2.0 Primary Assembly

    Genomic

    1. NC_037329.1 Reference ARS-UCD2.0 Primary Assembly

      Range
      131095754..131165879
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_015460372.3 → XP_015315858.2  rap1 GTPase-activating protein 1 isoform X3

      UniProtKB/TrEMBL
      A0A3S5ZPH9
      Conserved Domains (2) summary
      pfam02145
      Location:275 → 454
      Rap_GAP; Rap/ran-GAP
      pfam02188
      Location:61 → 81
      GoLoco; GoLoco motif

    2. XM_024975609.2 → XP_024831377.1  rap1 GTPase-activating protein 1 isoform X4

      UniProtKB/TrEMBL
      A0A3Q1MU40, A0A3S5ZPH9
      Related
      ENSBTAP00070013762.1, ENSBTAT00070023335.1
      Conserved Domains (2) summary
      pfam02145
      Location:275 → 454
      Rap_GAP; Rap/ran-GAP
      pfam02188
      Location:61 → 81
      GoLoco; GoLoco motif

    3. XM_059875135.1 → XP_059731118.1  rap1 GTPase-activating protein 1 isoform X1

      UniProtKB/TrEMBL
      A0A3Q1MS88, A0A3Q1N6Z7
      Related
      ENSBTAP00070013745.1, ENSBTAT00070023309.1

    4. XM_059875136.1 → XP_059731119.1  rap1 GTPase-activating protein 1 isoform X2

      UniProtKB/TrEMBL
      A0A3S5ZPH9
      Related
      ENSBTAP00070013754.1, ENSBTAT00070023325.1
    Nucleotide Protein Strain
    Heading Accession and Version

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