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    SUPT6H SPT6 homolog, histone chaperone and transcription elongation factor [ Bos taurus (domestic cattle) ]

    Gene ID: 538671, updated on 1-Jan-2025

    Summary

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    Official Symbol
    SUPT6Hprovided by VGNC
    Official Full Name
    SPT6 homolog, histone chaperone and transcription elongation factorprovided by VGNC
    Primary source
    VGNC:VGNC:50619
    See related
    BGD:BT14143; Ensembl:ENSBTAG00000009036
    Gene type
    protein coding
    RefSeq status
    PROVISIONAL
    Organism
    Bos taurus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Laurasiatheria; Artiodactyla; Ruminantia; Pecora; Bovidae; Bovinae; Bos
    Orthologs
    human mouse all
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    Genomic context

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    See SUPT6H in Genome Data Viewer
    Location:
    chromosome: 19
    Exon count:
    37
    Annotation release Status Assembly Chr Location
    RS_2024_12 current ARS-UCD2.0 (GCF_002263795.3) 19 NC_037346.1 (20098400..20129723)

    Chromosome 19 - NC_037346.1Genomic Context describing neighboring genes Neighboring gene KIAA0100 Neighboring gene uncharacterized LOC132343026 Neighboring gene stromal cell derived factor 2 Neighboring gene protein interacting with cyclin A1 Neighboring gene RAB34, member RAS oncogene family

    Genomic regions, transcripts, and products

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    Genomic Sequence:
    NC_037346.1 Chromosome 19 Reference ARS-UCD2.0 Primary Assembly

    Go to nucleotide: Graphics FASTA GenBank

    Expression

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    • Project title: Dominette sequence data
    • BioProject: PRJNA294306
    • Analysis date: Tue Dec 17 08:57:05 2024

    Bibliography

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    Related articles in PubMed

    1. A whole-genome assembly of the domestic cow, Bos taurus. Zimin AV, et al. Genome Biol, 2009. PMID 19393038, Free PMC Article
    2. Manual GO annotation of predictive protein signatures: the InterPro approach to GO curation. Burge S, et al. Database (Oxford), 2012. PMID 22301074, Free PMC Article
    3. TreeGrafter: phylogenetic tree-based annotation of proteins with Gene Ontology terms and other annotations. Tang H, et al. Bioinformatics, 2019 Feb 1. PMID 30032202, Free PMC Article

    GeneRIFs: Gene References Into Functions

    General gene information

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    Markers

    Homology

    Gene Ontology Provided by RefSeq

    Function Evidence Code Pubs
    enables DNA binding IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    enables histone binding IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    enables nucleosome binding IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    Process Evidence Code Pubs
    involved_in nucleosome organization IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    involved_in transcription elongation by RNA polymerase II IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    involved_in transcription elongation-coupled chromatin remodeling IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    Component Evidence Code Pubs
    part_of transcription elongation factor complex IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 

    General protein information

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    Preferred Names
    transcription elongation factor SPT6
    Names
    suppressor of Ty 6 homolog

    NCBI Reference Sequences (RefSeq)

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    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_001193126.1 → NP_001180055.1  transcription elongation factor SPT6

      See identical proteins and their annotated locations for NP_001180055.1

      Status: PROVISIONAL

      Source sequence(s)
      NKLS02000019
      UniProtKB/TrEMBL
      A0A3Q1LVF3
      Conserved Domains (2) summary
      pfam14633
      Location:1304 → 1514
      SH2_2; SH2 domain
      cl28255
      Location:372 → 1353
      Pnp; Polyribonucleotide nucleotidyltransferase (polynucleotide phosphorylase) [Translation, ribosomal structure and biogenesis]

    RefSeqs of Annotated Genomes: GCF_002263795.3-RS_2024_12

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference ARS-UCD2.0 Primary Assembly

    Genomic

    1. NC_037346.1 Reference ARS-UCD2.0 Primary Assembly

      Range
      20098400..20129723
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_005220111.5 → XP_005220168.1  transcription elongation factor SPT6 isoform X1

      See identical proteins and their annotated locations for XP_005220168.1

      UniProtKB/TrEMBL
      A0A3Q1LVF3
      Related
      ENSBTAP00000061169.1, ENSBTAT00000068168.2
      Conserved Domains (2) summary
      pfam14633
      Location:1304 → 1514
      SH2_2; SH2 domain
      cl28255
      Location:372 → 1353
      Pnp; Polyribonucleotide nucleotidyltransferase (polynucleotide phosphorylase) [Translation, ribosomal structure and biogenesis]

    2. XM_010815840.4 → XP_010814142.1  transcription elongation factor SPT6 isoform X1

      See identical proteins and their annotated locations for XP_010814142.1

      UniProtKB/TrEMBL
      A0A3Q1LVF3
      Conserved Domains (2) summary
      pfam14633
      Location:1304 → 1514
      SH2_2; SH2 domain
      cl28255
      Location:372 → 1353
      Pnp; Polyribonucleotide nucleotidyltransferase (polynucleotide phosphorylase) [Translation, ribosomal structure and biogenesis]
    Nucleotide Protein Strain
    Heading Accession and Version

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