U.S. flag

An official website of the United States government

Format

Send to:

Choose Destination

Links from GEO Profiles

    • Showing Current items.

    AOX1 aldehyde oxidase 1 [ Bos taurus (domestic cattle) ]

    Gene ID: 338074, updated on 1-Jan-2025

    Summary

    Go to the top of the page Help
    Official Symbol
    AOX1provided by VGNC
    Official Full Name
    aldehyde oxidase 1provided by VGNC
    Primary source
    VGNC:VGNC:25974
    See related
    BGD:BT20930; Ensembl:ENSBTAG00000009725
    Gene type
    protein coding
    RefSeq status
    PROVISIONAL
    Organism
    Bos taurus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Laurasiatheria; Artiodactyla; Ruminantia; Pecora; Bovidae; Bovinae; Bos
    Orthologs
    human mouse all
    NEW
    Try the new Gene table
    Try the new Transcript table

    Genomic context

    Go to the top of the page Help
    See AOX1 in Genome Data Viewer
    Location:
    chromosome: 2
    Exon count:
    36
    Annotation release Status Assembly Chr Location
    RS_2024_12 current ARS-UCD2.0 (GCF_002263795.3) 2 NC_037329.1 (89102187..89173909)

    Chromosome 2 - NC_037329.1Genomic Context describing neighboring genes Neighboring gene potassium channel tetramerization domain containing 18 Neighboring gene shugoshin 2 Neighboring gene biogenesis of lysosome-related organelles complex 1 subunit 1-like Neighboring gene aldehyde oxidase 4 Neighboring gene aldehyde oxidase 2 Neighboring gene uncharacterized LOC112442951

    Genomic regions, transcripts, and products

    Go to the top of the page Help
    Genomic Sequence:
    NC_037329.1 Chromosome 2 Reference ARS-UCD2.0 Primary Assembly

    Go to nucleotide: Graphics FASTA GenBank

    Expression

    Go to the top of the page Help
    • Project title: Dominette sequence data
    • BioProject: PRJNA294306
    • Analysis date: Tue Dec 17 08:57:05 2024

    Bibliography

    Go to the top of the pageHelp

    Related articles in PubMed

    1. Purification, cDNA cloning, and tissue distribution of bovine liver aldehyde oxidase. Calzi ML, et al. J Biol Chem, 1995 Dec 29. PMID 8537361
    2. Structure and evolution of vertebrate aldehyde oxidases: from gene duplication to gene suppression. Kurosaki M, et al. Cell Mol Life Sci, 2013 May. PMID 23263164, Free PMC Article
    3. A whole-genome assembly of the domestic cow, Bos taurus. Zimin AV, et al. Genome Biol, 2009. PMID 19393038, Free PMC Article
    4. Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. Strausberg RL, et al. Proc Natl Acad Sci U S A, 2002 Dec 24. PMID 12477932, Free PMC Article
    5. Manual GO annotation of predictive protein signatures: the InterPro approach to GO curation. Burge S, et al. Database (Oxford), 2012. PMID 22301074, Free PMC Article

    See all (6) citations in PubMed

    GeneRIFs: Gene References Into Functions

    Pathways from PubChem

    Go to the top of the page

    General gene information

    Go to the top of the page Help

    Markers

    Homology

    Clone Names

    • MGC128959

    Gene Ontology Provided by RefSeq

    Function Evidence Code Pubs
    enables 2 iron, 2 sulfur cluster binding IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    enables FAD binding IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    enables NAD binding IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    enables aldehyde oxidase activity IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    enables iron ion binding IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    enables molybdopterin cofactor binding IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 

    General protein information

    Go to the top of the page Help
    Preferred Names
    aldehyde oxidase 1
    Names
    azaheterocycle hydroxylase 1
    NP_788841.1
    XP_024855122.1

    NCBI Reference Sequences (RefSeq)

    Go to the top of the page Help

    NEW Try the new Transcript table

    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_176668.3 → NP_788841.1  aldehyde oxidase 1

      See identical proteins and their annotated locations for NP_788841.1

      Status: PROVISIONAL

      Source sequence(s)
      X87251
      UniProtKB/Swiss-Prot
      P48034, Q3MHE7
      UniProtKB/TrEMBL
      F1MRY9
      Related
      ENSBTAP00000012827.6, ENSBTAT00000012827.6
      Conserved Domains (6) summary
      TIGR02969
      Location:5 → 1339
      mam_aldehyde_ox; aldehyde oxidase
      pfam00941
      Location:240 → 419
      FAD_binding_5; FAD binding domain in molybdopterin dehydrogenase
      pfam01315
      Location:594 → 702
      Ald_Xan_dh_C; Aldehyde oxidase and xanthine dehydrogenase, a/b hammerhead domain
      pfam01799
      Location:88 → 161
      Fer2_2; [2Fe-2S] binding domain
      pfam02738
      Location:715 → 1246
      Ald_Xan_dh_C2; Molybdopterin-binding domain of aldehyde dehydrogenase
      pfam03450
      Location:426 → 530
      CO_deh_flav_C; CO dehydrogenase flavoprotein C-terminal domain

    RefSeqs of Annotated Genomes: GCF_002263795.3-RS_2024_12

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference ARS-UCD2.0 Primary Assembly

    Genomic

    1. NC_037329.1 Reference ARS-UCD2.0 Primary Assembly

      Range
      89102187..89173909
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_024999354.2 → XP_024855122.1  aldehyde oxidase 1 isoform X1

      UniProtKB/TrEMBL
      F1MRY9
      Conserved Domains (1) summary
      cl27380
      Location:1 → 1314
      Ald_Xan_dh_C2; Molybdopterin-binding domain of aldehyde dehydrogenase
    Nucleotide Protein Strain
    Heading Accession and Version
    Protein Accession Links
    GenPept Link UniProtKB Link
    P48034.2 GenPept UniProtKB/Swiss-Prot:P48034

    Gene LinkOut

    The following LinkOut resources are supplied by external providers. These providers are responsible for maintaining the links.

    Molecular Biology Databases
    Research Materials