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    HSF4 heat shock transcription factor 4 [ Bos taurus (domestic cattle) ]

    Gene ID: 614788, updated on 27-Dec-2024

    Summary

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    Official Symbol
    HSF4provided by VGNC
    Official Full Name
    heat shock transcription factor 4provided by VGNC
    Primary source
    VGNC:VGNC:29984
    See related
    BGD:BT13684; Ensembl:ENSBTAG00000003514
    Gene type
    protein coding
    RefSeq status
    VALIDATED
    Organism
    Bos taurus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Laurasiatheria; Artiodactyla; Ruminantia; Pecora; Bovidae; Bovinae; Bos
    Orthologs
    human mouse all
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    Genomic context

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    See HSF4 in Genome Data Viewer
    Location:
    chromosome: 18
    Exon count:
    13
    Annotation release Status Assembly Chr Location
    RS_2024_12 current ARS-UCD2.0 (GCF_002263795.3) 18 NC_037345.1 (34803086..34807857)

    Chromosome 18 - NC_037345.1Genomic Context describing neighboring genes Neighboring gene uncharacterized LOC132342821 Neighboring gene TNFRSF1A associated via death domain Neighboring gene F-box and leucine rich repeat protein 8 Neighboring gene nucleolar protein 3 Neighboring gene microtubule associated tyrosine carboxypeptidase 1

    Genomic regions, transcripts, and products

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    Genomic Sequence:
    NC_037345.1 Chromosome 18 Reference ARS-UCD2.0 Primary Assembly

    Go to nucleotide: Graphics FASTA GenBank

    Expression

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    • Project title: Dominette sequence data
    • BioProject: PRJNA294306
    • Analysis date: Tue Dec 17 08:57:05 2024

    Bibliography

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    Related articles in PubMed

    1. Sequence evaluation of four pooled-tissue normalized bovine cDNA libraries and construction of a gene index for cattle. Smith TP, et al. Genome Res, 2001 Apr. PMID 11282978, Free PMC Article
    2. A whole-genome assembly of the domestic cow, Bos taurus. Zimin AV, et al. Genome Biol, 2009. PMID 19393038, Free PMC Article
    3. Manual GO annotation of predictive protein signatures: the InterPro approach to GO curation. Burge S, et al. Database (Oxford), 2012. PMID 22301074, Free PMC Article

    GeneRIFs: Gene References Into Functions

    General gene information

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    Markers

    Homology

    Gene Ontology Provided by RefSeq

    Function Evidence Code Pubs
    enables DNA-binding transcription factor activity IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    enables sequence-specific DNA binding IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    Process Evidence Code Pubs
    involved_in regulation of DNA-templated transcription IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 

    General protein information

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    Preferred Names
    heat shock factor protein 4

    NCBI Reference Sequences (RefSeq)

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    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_001191202.1 → NP_001178131.1  heat shock factor protein 4

      See identical proteins and their annotated locations for NP_001178131.1

      Status: VALIDATED

      Source sequence(s)
      BM106949, CK773361, CN786860, DV892633, DY048372
      UniProtKB/TrEMBL
      A0AAA9TEZ1
      Conserved Domains (3) summary
      smart00415
      Location:16 → 120
      HSF; heat shock factor
      pfam06546
      Location:258 → 489
      Vert_HS_TF; Vertebrate heat shock transcription factor
      pfam15035
      Location:110 → 175
      Rootletin; Ciliary rootlet component, centrosome cohesion

    RefSeqs of Annotated Genomes: GCF_002263795.3-RS_2024_12

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference ARS-UCD2.0 Primary Assembly

    Genomic

    1. NC_037345.1 Reference ARS-UCD2.0 Primary Assembly

      Range
      34803086..34807857
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_005218720.5 → XP_005218777.1  heat shock factor protein 4 isoform X7

      See identical proteins and their annotated locations for XP_005218777.1

      Conserved Domains (2) summary
      smart00415
      Location:16 → 120
      HSF; heat shock factor
      pfam15035
      Location:110 → 175
      Rootletin; Ciliary rootlet component, centrosome cohesion

    2. XM_010814556.4 → XP_010812858.1  heat shock factor protein 4 isoform X1

      UniProtKB/TrEMBL
      A0AAA9TEZ1
      Conserved Domains (2) summary
      smart00415
      Location:16 → 120
      HSF; heat shock factor
      pfam15035
      Location:110 → 175
      Rootletin; Ciliary rootlet component, centrosome cohesion

    3. XM_005218719.5 → XP_005218776.1  heat shock factor protein 4 isoform X2

      UniProtKB/TrEMBL
      A0AAA9TEZ1
      Conserved Domains (2) summary
      smart00415
      Location:16 → 120
      HSF; heat shock factor
      pfam15035
      Location:110 → 175
      Rootletin; Ciliary rootlet component, centrosome cohesion

    4. XM_010814558.3 → XP_010812860.1  heat shock factor protein 4 isoform X4

      UniProtKB/TrEMBL
      A0AAA9TEZ1, F1MVT6
      Related
      ENSBTAP00000004568.5, ENSBTAT00000004568.6
      Conserved Domains (3) summary
      smart00415
      Location:16 → 120
      HSF; heat shock factor
      pfam06546
      Location:258 → 443
      Vert_HS_TF; Vertebrate heat shock transcription factor
      pfam15035
      Location:110 → 175
      Rootletin; Ciliary rootlet component, centrosome cohesion

    5. XM_059876895.1 → XP_059732878.1  heat shock factor protein 4 isoform X5

    6. XM_059876897.1 → XP_059732880.1  heat shock factor protein 4 isoform X6

    7. XM_010814557.4 → XP_010812859.1  heat shock factor protein 4 isoform X3

      UniProtKB/TrEMBL
      A0AAA9TEZ1
      Conserved Domains (2) summary
      smart00415
      Location:16 → 120
      HSF; heat shock factor
      pfam15035
      Location:110 → 175
      Rootletin; Ciliary rootlet component, centrosome cohesion
    Nucleotide Protein Strain
    Heading Accession and Version

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