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    PCDH12 protocadherin 12 [ Bos taurus (domestic cattle) ]

    Gene ID: 540115, updated on 30-Jan-2025

    Summary

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    Official Symbol
    PCDH12provided by VGNC
    Official Full Name
    protocadherin 12provided by VGNC
    Primary source
    VGNC:VGNC:32616
    See related
    BGD:BT29670; EnsemblRapid:ENSBTAG00070030901
    Gene type
    protein coding
    RefSeq status
    PROVISIONAL
    Organism
    Bos taurus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Laurasiatheria; Artiodactyla; Ruminantia; Pecora; Bovidae; Bovinae; Bos
    Orthologs
    human mouse all
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    Genomic context

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    See PCDH12 in Genome Data Viewer
    Location:
    chromosome: 7
    Exon count:
    5
    Annotation release Status Assembly Chr Location
    RS_2024_12 current ARS-UCD2.0 (GCF_002263795.3) 7 NC_037334.1 (53008892..53021661, complement)

    Chromosome 7 - NC_037334.1Genomic Context describing neighboring genes Neighboring gene uncharacterized LOC104969197 Neighboring gene DAP3 binding cell death enhancer 1 Neighboring gene ring finger protein 14 Neighboring gene glucosamine-6-phosphate deaminase 1 Neighboring gene Nedd4 family interacting protein 1

    Genomic regions, transcripts, and products

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    Genomic Sequence:
    NC_037334.1 Chromosome 7 Reference ARS-UCD2.0 Primary Assembly

    Go to nucleotide: Graphics FASTA GenBank

    Expression

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    • Project title: Dominette sequence data
    • BioProject: PRJNA294306
    • Analysis date: Tue Dec 17 08:57:05 2024

    Bibliography

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    Related articles in PubMed

    1. A whole-genome assembly of the domestic cow, Bos taurus. Zimin AV, et al. Genome Biol, 2009. PMID 19393038, Free PMC Article
    2. Manual GO annotation of predictive protein signatures: the InterPro approach to GO curation. Burge S, et al. Database (Oxford), 2012. PMID 22301074, Free PMC Article
    3. TreeGrafter: phylogenetic tree-based annotation of proteins with Gene Ontology terms and other annotations. Tang H, et al. Bioinformatics, 2019 Feb 1. PMID 30032202, Free PMC Article

    GeneRIFs: Gene References Into Functions

    General gene information

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    Markers

    Homology

    Clone Names

    • MGC149025

    Gene Ontology Provided by RefSeq

    Function Evidence Code Pubs
    enables calcium ion binding IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    Process Evidence Code Pubs
    involved_in homophilic cell adhesion via plasma membrane adhesion molecules IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    Component Evidence Code Pubs
    located_in plasma membrane IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 

    General protein information

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    Preferred Names
    protocadherin-12

    NCBI Reference Sequences (RefSeq)

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    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_001098111.1 → NP_001091580.1  protocadherin-12 precursor

      See identical proteins and their annotated locations for NP_001091580.1

      Status: PROVISIONAL

      Source sequence(s)
      BC140692
      UniProtKB/TrEMBL
      A5D7V2, F1N0X0
      Related
      ENSBTAP00070042580.1, ENSBTAT00070069968.1
      Conserved Domains (2) summary
      cd11304
      Location:250 → 347
      Cadherin_repeat; Cadherin tandem repeat domain
      cl09101
      Location:30 → 110
      E_set; Early set domain associated with the catalytic domain of sugar utilizing enzymes at either the N or C terminus

    RefSeqs of Annotated Genomes: GCF_002263795.3-RS_2024_12

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference ARS-UCD2.0 Primary Assembly

    Genomic

    1. NC_037334.1 Reference ARS-UCD2.0 Primary Assembly

      Range
      53008892..53021661 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_010807361.4 → XP_010805663.1  protocadherin-12 isoform X1

      UniProtKB/TrEMBL
      F1N0X0
      Conserved Domains (2) summary
      cd11304
      Location:250 → 347
      Cadherin_repeat; Cadherin tandem repeat domain
      cl09101
      Location:30 → 110
      E_set; Early set domain associated with the catalytic domain of sugar utilizing enzymes at either the N or C terminus
    Nucleotide Protein Strain
    Heading Accession and Version

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