SPSB2 splA/ryanodine receptor domain and SOCS box containing 2 [Bos taurus (domestic cattle)] - Gene

Summary

Official Symbol: SPSB2provided by VGNC
Official Full Name: splA/ryanodine receptor domain and SOCS box containing 2provided by VGNC
Primary source: VGNC:VGNC:50141
See related: BGD:BT30204; Ensembl:ENSBTAG00000053346
Gene type: protein coding
RefSeq status: PROVISIONAL
Organism: Bos taurus
Lineage: Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Laurasiatheria; Artiodactyla; Ruminantia; Pecora; Bovidae; Bovinae; Bos
Orthologs: human mouse all
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Genomic context

Location:: chromosome: 5

Exon count:: 3

Annotation release	Status	Assembly	Chr	Location
RS_2024_12	current	ARS-UCD2.0 (GCF_002263795.3)	5	NC_037332.1 (103576908..103580006)

Chromosome 5 - NC_037332.1 Genomic Context describing neighboring genes

Genomic regions, transcripts, and products

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Go to reference sequence details

Genomic Sequence:: NC_037332.1 Chromosome 5 Reference ARS-UCD2.0 Primary Assembly

Go to nucleotide: Graphics FASTA GenBank

Expression

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See details

Project title: Dominette sequence data
BioProject: PRJNA294306
Analysis date: Tue Dec 17 08:57:05 2024

Bibliography

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GeneRIFs: Gene References Into Functions

What's a GeneRIF?

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General gene information

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Gene Ontology Provided by RefSeq

Function	Evidence Code	Pubs
enables protein binding	IEA Inferred from Electronic Annotation more info	PubMed

Process	Evidence Code	Pubs
involved_in intracellular signal transduction	IEA Inferred from Electronic Annotation more info	PubMed
involved_in proteasome-mediated ubiquitin-dependent protein catabolic process	IEA Inferred from Electronic Annotation more info	PubMed

Component	Evidence Code	Pubs
part_of SCF ubiquitin ligase complex	IEA Inferred from Electronic Annotation more info	PubMed

General protein information

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Preferred Names: SPRY domain-containing SOCS box protein 2

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

NM_001076280.1 → NP_001069748.1 SPRY domain-containing SOCS box protein 2

See identical proteins and their annotated locations for NP_001069748.1

Status: PROVISIONAL

Source sequence(s)

BC118107

UniProtKB/TrEMBL

A0A3Q1MJT8, Q17QZ2

Related

ENSBTAP00000090776.1, ENSBTAT00000093343.1

Conserved Domains (1) summary

cd12906
Location:46 → 217

SPRY_SOCS1-2-4; SPRY domain in the suppressor of cytokine signaling 1, 2, 4 families (SOCS1, SOCS2, SOCS4)

RefSeqs of Annotated Genomes: GCF_002263795.3-RS_2024_12

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference ARS-UCD2.0 Primary Assembly

Genomic

NC_037332.1 Reference ARS-UCD2.0 Primary Assembly

Range

103576908..103580006

Download

GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

XM_015471310.3 → XP_015326796.1 SPRY domain-containing SOCS box protein 2 isoform X1

UniProtKB/TrEMBL

A0A3Q1MJT8, Q17QZ2

Conserved Domains (1) summary

cd12906
Location:46 → 217

SPRY_SOCS1-2-4; SPRY domain in the suppressor of cytokine signaling 1, 2, 4 families (SOCS1, SOCS2, SOCS4)
XM_005207162.5 → XP_005207219.1 SPRY domain-containing SOCS box protein 2 isoform X2

UniProtKB/TrEMBL

A0AAA9SWJ4

Conserved Domains (2) summary

cd12906
Location:46 → 217

SPRY_SOCS1-2-4; SPRY domain in the suppressor of cytokine signaling 1, 2, 4 families (SOCS1, SOCS2, SOCS4)

cl02533
Location:222 → 263

SOCS; SOCS (suppressors of cytokine signaling) box. The SOCS box is found in the C-terminal region of CIS/SOCS family proteins (in combination with a SH2 domain), ASBs (ankyrin repeat-containing proteins with a SOCS box), SSBs (SPRY domain-containing proteins ...