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    ARL2 ADP ribosylation factor like GTPase 2 [ Bos taurus (domestic cattle) ]

    Gene ID: 511349, updated on 27-Dec-2024

    Summary

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    Official Symbol
    ARL2provided by VGNC
    Official Full Name
    ADP ribosylation factor like GTPase 2provided by VGNC
    Primary source
    VGNC:VGNC:97240
    See related
    BGD:BT11737; Ensembl:ENSBTAG00000002238
    Gene type
    protein coding
    RefSeq status
    PROVISIONAL
    Organism
    Bos taurus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Laurasiatheria; Artiodactyla; Ruminantia; Pecora; Bovidae; Bovinae; Bos
    Orthologs
    human mouse all
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    Genomic context

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    See ARL2 in Genome Data Viewer
    Location:
    chromosome: 29
    Exon count:
    7
    Annotation release Status Assembly Chr Location
    RS_2024_12 current ARS-UCD2.0 (GCF_002263795.3) 29 NC_037356.1 (43227243..43235043)

    Chromosome 29 - NC_037356.1Genomic Context describing neighboring genes Neighboring gene membrane anchored junction protein Neighboring gene uncharacterized LOC132344207 Neighboring gene basic leucine zipper ATF-like transcription factor 2 Neighboring gene sorting nexin 15 Neighboring gene N-acetylated alpha-linked acidic dipeptidase like 1 Neighboring gene SAC3 domain containing 1

    Genomic regions, transcripts, and products

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    Genomic Sequence:
    NC_037356.1 Chromosome 29 Reference ARS-UCD2.0 Primary Assembly

    Go to nucleotide: Graphics FASTA GenBank

    Expression

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    • Project title: Dominette sequence data
    • BioProject: PRJNA294306
    • Analysis date: Tue Dec 17 08:57:05 2024

    Bibliography

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    Related articles in PubMed

    1. Beta-tubulin cofactor D and ARL2 take part in apical junctional complex disassembly and abrogate epithelial structure. Shultz T, et al. FASEB J, 2008 Jan. PMID 17704193
    2. ELMOD2 is an Arl2 GTPase-activating protein that also acts on Arfs. Bowzard JB, et al. J Biol Chem, 2007 Jun 15. PMID 17452337
    3. Cytosolic Arl2 is complexed with cofactor D and protein phosphatase 2A. Shern JF, et al. J Biol Chem, 2003 Oct 17. PMID 12912990
    4. A whole-genome assembly of the domestic cow, Bos taurus. Zimin AV, et al. Genome Biol, 2009. PMID 19393038, Free PMC Article
    5. Manual GO annotation of predictive protein signatures: the InterPro approach to GO curation. Burge S, et al. Database (Oxford), 2012. PMID 22301074, Free PMC Article

    See all (6) citations in PubMed

    GeneRIFs: Gene References Into Functions

    Pathways from PubChem

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    General gene information

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    Homology

    Clone Names

    • MGC134005

    Gene Ontology Provided by RefSeq

    Function Evidence Code Pubs
    enables GTP binding IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    enables GTPase activity IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    Process Evidence Code Pubs
    involved_in protein folding IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    Component Evidence Code Pubs
    located_in cytoplasm IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    located_in microtubule cytoskeleton IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 

    General protein information

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    Preferred Names
    ADP-ribosylation factor-like protein 2
    Names
    ADP-ribosylation factor-like 2

    NCBI Reference Sequences (RefSeq)

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    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_001038079.2 → NP_001033168.1  ADP-ribosylation factor-like protein 2

      See identical proteins and their annotated locations for NP_001033168.1

      Status: PROVISIONAL

      Source sequence(s)
      BC111133
      UniProtKB/Swiss-Prot
      Q2TA37
      Related
      ENSBTAP00000002890.3, ENSBTAT00000002890.4
      Conserved Domains (1) summary
      cd04154
      Location:3 → 175
      Arl2; Arf-like 2 (Arl2) GTPase

    RefSeqs of Annotated Genomes: GCF_002263795.3-RS_2024_12

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference ARS-UCD2.0 Primary Assembly

    Genomic

    1. NC_037356.1 Reference ARS-UCD2.0 Primary Assembly

      Range
      43227243..43235043
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_059882846.1 → XP_059738829.1  ADP-ribosylation factor-like protein 2 isoform X1

    2. XM_024987063.1 → XP_024842831.1  ADP-ribosylation factor-like protein 2 isoform X1

      Conserved Domains (1) summary
      cd04154
      Location:27 → 179
      Arl2; Arf-like 2 (Arl2) GTPase
    Nucleotide Protein Strain
    Heading Accession and Version
    Protein Accession Links
    GenPept Link UniProtKB Link
    Q2TA37.1 GenPept UniProtKB/Swiss-Prot:Q2TA37

    Gene LinkOut

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