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    STXBP5 syntaxin binding protein 5 [ Bos taurus (domestic cattle) ]

    Gene ID: 537603, updated on 27-Dec-2024

    Summary

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    Official Symbol
    STXBP5provided by VGNC
    Official Full Name
    syntaxin binding protein 5provided by VGNC
    Primary source
    VGNC:VGNC:35448
    See related
    BGD:BT10169; Ensembl:ENSBTAG00000021107
    Gene type
    protein coding
    RefSeq status
    PROVISIONAL
    Organism
    Bos taurus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Laurasiatheria; Artiodactyla; Ruminantia; Pecora; Bovidae; Bovinae; Bos
    Orthologs
    human mouse all
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    Genomic context

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    See STXBP5 in Genome Data Viewer
    Location:
    chromosome: 9
    Exon count:
    30
    Annotation release Status Assembly Chr Location
    RS_2024_12 current ARS-UCD2.0 (GCF_002263795.3) 9 NC_037336.1 (84506097..84664023)

    Chromosome 9 - NC_037336.1Genomic Context describing neighboring genes Neighboring gene medium-chain specific acyl-CoA dehydrogenase, mitochondrial Neighboring gene androglobin Neighboring gene calcium-independent phospholipase A2-gamma-like Neighboring gene tyrosine-protein kinase RYK-like Neighboring gene UL16-binding protein 3 Neighboring gene UL16-binding protein 3-like

    Genomic regions, transcripts, and products

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    Genomic Sequence:
    NC_037336.1 Chromosome 9 Reference ARS-UCD2.0 Primary Assembly

    Go to nucleotide: Graphics FASTA GenBank

    Expression

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    • Project title: Dominette sequence data
    • BioProject: PRJNA294306
    • Analysis date: Tue Dec 17 08:57:05 2024

    Bibliography

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    Related articles in PubMed

    1. Receptor-mediated regulation of tomosyn-syntaxin 1A interactions in bovine adrenal chromaffin cells. Gladycheva SE, et al. J Biol Chem, 2007 Aug 3. PMID 17545156
    2. Genomic organization and evolution of the ULBP genes in cattle. Larson JH, et al. BMC Genomics, 2006 Sep 5. PMID 16953885, Free PMC Article
    3. A whole-genome assembly of the domestic cow, Bos taurus. Zimin AV, et al. Genome Biol, 2009. PMID 19393038, Free PMC Article
    4. TreeGrafter: phylogenetic tree-based annotation of proteins with Gene Ontology terms and other annotations. Tang H, et al. Bioinformatics, 2019 Feb 1. PMID 30032202, Free PMC Article

    GeneRIFs: Gene References Into Functions

    General gene information

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    Homology

    Gene Ontology Provided by RefSeq

    Function Evidence Code Pubs
    enables GTPase activator activity IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    enables myosin II binding IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    enables syntaxin binding IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    Process Evidence Code Pubs
    involved_in regulation of exocytosis IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    involved_in regulation of protein secretion IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    Component Evidence Code Pubs
    part_of SNARE complex IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    located_in cytoplasm IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    located_in plasma membrane IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 

    General protein information

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    Preferred Names
    syntaxin-binding protein 5

    NCBI Reference Sequences (RefSeq)

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    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_001191540.1 → NP_001178469.1  syntaxin-binding protein 5

      See identical proteins and their annotated locations for NP_001178469.1

      Status: PROVISIONAL

      Source sequence(s)
      NKLS02000009
      UniProtKB/TrEMBL
      A0AAA9SMC8
      Related
      ENSBTAP00000069753.1, ENSBTAT00000082509.2
      Conserved Domains (5) summary
      COG2319
      Location:100 → 493
      WD40; WD40 repeat [General function prediction only]
      cd15893
      Location:1085 → 1145
      R-SNARE_STXBP5; SNARE domain of STXBP5
      pfam08366
      Location:277 → 384
      LLGL; LLGL2
      sd00039
      Location:62 → 95
      7WD40; WD40 repeat [structural motif]
      cl02567
      Location:62 → 280
      WD40; WD40 domain, found in a number of eukaryotic proteins that cover a wide variety of functions including adaptor/regulatory modules in signal transduction, pre-mRNA processing and cytoskeleton assembly; typically contains a GH dipeptide 11-24 residues from ...

    RefSeqs of Annotated Genomes: GCF_002263795.3-RS_2024_12

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference ARS-UCD2.0 Primary Assembly

    Genomic

    1. NC_037336.1 Reference ARS-UCD2.0 Primary Assembly

      Range
      84506097..84664023
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_015472897.3 → XP_015328383.1  syntaxin-binding protein 5 isoform X2

      UniProtKB/TrEMBL
      A0A3Q1LKT6, A0AAA9SMC8
      Related
      ENSBTAP00000057082.1, ENSBTAT00000073234.2
      Conserved Domains (5) summary
      COG2319
      Location:64 → 489
      WD40; WD40 repeat [General function prediction only]
      cd15893
      Location:1069 → 1129
      R-SNARE_STXBP5; SNARE domain of STXBP5
      pfam08366
      Location:277 → 384
      LLGL; LLGL2
      sd00039
      Location:62 → 95
      7WD40; WD40 repeat [structural motif]
      cl02567
      Location:62 → 280
      WD40; WD40 domain, found in a number of eukaryotic proteins that cover a wide variety of functions including adaptor/regulatory modules in signal transduction, pre-mRNA processing and cytoskeleton assembly; typically contains a GH dipeptide 11-24 residues from ...

    2. XM_005211027.5 → XP_005211084.1  syntaxin-binding protein 5 isoform X3

      See identical proteins and their annotated locations for XP_005211084.1

      UniProtKB/TrEMBL
      A0A3Q1LW14, A0AAA9SMC8
      Related
      ENSBTAP00000059562.1, ENSBTAT00000083985.2
      Conserved Domains (5) summary
      COG2319
      Location:64 → 489
      WD40; WD40 repeat [General function prediction only]
      cd15893
      Location:1049 → 1109
      R-SNARE_STXBP5; SNARE domain of STXBP5
      pfam08366
      Location:277 → 384
      LLGL; LLGL2
      sd00039
      Location:62 → 95
      7WD40; WD40 repeat [structural motif]
      cl02567
      Location:62 → 280
      WD40; WD40 domain, found in a number of eukaryotic proteins that cover a wide variety of functions including adaptor/regulatory modules in signal transduction, pre-mRNA processing and cytoskeleton assembly; typically contains a GH dipeptide 11-24 residues from ...

    3. XM_024996769.2 → XP_024852537.1  syntaxin-binding protein 5 isoform X1

      UniProtKB/TrEMBL
      A0AAA9SMC8, E1BNK4
      Related
      ENSBTAP00000053504.3, ENSBTAT00000061280.4
      Conserved Domains (5) summary
      COG2319
      Location:237 → 539
      WD40; WD40 repeat [General function prediction only]
      cd15893
      Location:1084 → 1144
      R-SNARE_STXBP5; SNARE domain of STXBP5
      sd00039
      Location:62 → 95
      7WD40; WD40 repeat [structural motif]
      pfam08366
      Location:277 → 384
      LLGL; LLGL2
      cl25539
      Location:62 → 280
      WD40; WD40 domain, found in a number of eukaryotic proteins that cover a wide variety of functions including adaptor/regulatory modules in signal transduction, pre-mRNA processing and cytoskeleton assembly; typically contains a GH dipeptide 11-24 residues from ...

    4. XM_024996771.2 → XP_024852539.1  syntaxin-binding protein 5 isoform X4

      UniProtKB/TrEMBL
      A0AAA9SMC8
      Conserved Domains (5) summary
      COG2319
      Location:237 → 539
      WD40; WD40 repeat [General function prediction only]
      cd15893
      Location:1048 → 1108
      R-SNARE_STXBP5; SNARE domain of STXBP5
      sd00039
      Location:62 → 95
      7WD40; WD40 repeat [structural motif]
      pfam08366
      Location:277 → 384
      LLGL; LLGL2
      cl25539
      Location:62 → 280
      WD40; WD40 domain, found in a number of eukaryotic proteins that cover a wide variety of functions including adaptor/regulatory modules in signal transduction, pre-mRNA processing and cytoskeleton assembly; typically contains a GH dipeptide 11-24 residues from ...

    5. XM_059889790.1 → XP_059745773.1  syntaxin-binding protein 5 isoform X5

    Nucleotide Protein Strain
    Heading Accession and Version

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