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    TNFRSF25 TNF receptor superfamily member 25 [ Bos taurus (domestic cattle) ]

    Gene ID: 783432, updated on 30-Jan-2025

    Summary

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    Official Symbol
    TNFRSF25provided by VGNC
    Official Full Name
    TNF receptor superfamily member 25provided by VGNC
    Primary source
    VGNC:VGNC:36167
    See related
    BGD:BT11052; EnsemblRapid:ENSBTAG00070017970
    Gene type
    protein coding
    RefSeq status
    INFERRED
    Organism
    Bos taurus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Laurasiatheria; Artiodactyla; Ruminantia; Pecora; Bovidae; Bovinae; Bos
    Also known as
    TNFRSF12
    Orthologs
    human mouse all
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    Genomic context

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    See TNFRSF25 in Genome Data Viewer
    Location:
    chromosome: 16
    Exon count:
    9
    Annotation release Status Assembly Chr Location
    RS_2024_12 current ARS-UCD2.0 (GCF_002263795.3) 16 NC_037343.1 (46904489..46909417)

    Chromosome 16 - NC_037343.1Genomic Context describing neighboring genes Neighboring gene nucleolar protein 9 Neighboring gene pleckstrin homology and RhoGEF domain containing G5 Neighboring gene espin Neighboring gene hes family bHLH transcription factor 2

    Genomic regions, transcripts, and products

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    Genomic Sequence:
    NC_037343.1 Chromosome 16 Reference ARS-UCD2.0 Primary Assembly

    Go to nucleotide: Graphics FASTA GenBank

    Expression

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    • Project title: Dominette sequence data
    • BioProject: PRJNA294306
    • Analysis date: Tue Dec 17 08:57:05 2024

    Bibliography

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    Related articles in PubMed

    1. A whole-genome assembly of the domestic cow, Bos taurus. Zimin AV, et al. Genome Biol, 2009. PMID 19393038, Free PMC Article
    2. Manual GO annotation of predictive protein signatures: the InterPro approach to GO curation. Burge S, et al. Database (Oxford), 2012. PMID 22301074, Free PMC Article
    3. TreeGrafter: phylogenetic tree-based annotation of proteins with Gene Ontology terms and other annotations. Tang H, et al. Bioinformatics, 2019 Feb 1. PMID 30032202, Free PMC Article

    GeneRIFs: Gene References Into Functions

    Pathways from PubChem

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    General gene information

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    Markers

    Homology

    Gene Ontology Provided by RefSeq

    Function Evidence Code Pubs
    enables protein binding IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    Process Evidence Code Pubs
    involved_in signal transduction IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    Component Evidence Code Pubs
    located_in plasma membrane IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 

    General protein information

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    Preferred Names
    tumor necrosis factor receptor superfamily member 25
    Names
    translocating chain-association membrane protein
    tumor necrosis factor receptor superfamily, member 25
    tumor necrosis factor receptor superfamily, member12

    NCBI Reference Sequences (RefSeq)

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    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_001144077.1 → NP_001137549.1  tumor necrosis factor receptor superfamily member 25 precursor

      See identical proteins and their annotated locations for NP_001137549.1

      Status: INFERRED

      Source sequence(s)
      NKLS02000016
      UniProtKB/TrEMBL
      E1BHL8
      Related
      ENSBTAP00070024045.1, ENSBTAT00070040513.1
      Conserved Domains (3) summary
      cd13420
      Location:35 → 148
      TNFRSF25; tumor necrosis factor receptor superfamily member 25 (TNFRSF25), also known as death receptor 3 (DR3)
      cl14633
      Location:335 → 411
      DD; Death Domain Superfamily of protein-protein interaction domains
      cl22855
      Location:141 → 173
      TNFRSF; Tumor necrosis factor receptor superfamily (TNFRSF)

    RefSeqs of Annotated Genomes: GCF_002263795.3-RS_2024_12

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference ARS-UCD2.0 Primary Assembly

    Genomic

    1. NC_037343.1 Reference ARS-UCD2.0 Primary Assembly

      Range
      46904489..46909417
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_005217148.5 → XP_005217205.1  tumor necrosis factor receptor superfamily member 25 isoform X1

      UniProtKB/TrEMBL
      E1BHL8
      Conserved Domains (3) summary
      cd13420
      Location:62 → 175
      TNFRSF25; tumor necrosis factor receptor superfamily member 25 (TNFRSF25), also known as death receptor 3 (DR3)
      cl14633
      Location:366 → 442
      DD; Death Domain Superfamily of protein-protein interaction domains
      cl22855
      Location:168 → 200
      TNFRSF; Tumor necrosis factor receptor superfamily (TNFRSF)

    2. XM_010813376.4 → XP_010811678.1  tumor necrosis factor receptor superfamily member 25 isoform X5

      UniProtKB/TrEMBL
      E1BHL8
      Conserved Domains (3) summary
      cd13420
      Location:62 → 175
      TNFRSF25; tumor necrosis factor receptor superfamily member 25 (TNFRSF25), also known as death receptor 3 (DR3)
      cl14633
      Location:327 → 403
      DD; Death Domain Superfamily of protein-protein interaction domains
      cl22855
      Location:168 → 200
      TNFRSF; Tumor necrosis factor receptor superfamily (TNFRSF)

    3. XM_005217149.5 → XP_005217206.1  tumor necrosis factor receptor superfamily member 25 isoform X2

      UniProtKB/TrEMBL
      E1BHL8
      Conserved Domains (3) summary
      cd13420
      Location:62 → 175
      TNFRSF25; tumor necrosis factor receptor superfamily member 25 (TNFRSF25), also known as death receptor 3 (DR3)
      cl14633
      Location:365 → 441
      DD; Death Domain Superfamily of protein-protein interaction domains
      cl22855
      Location:168 → 200
      TNFRSF; Tumor necrosis factor receptor superfamily (TNFRSF)

    4. XM_010813377.4 → XP_010811679.1  tumor necrosis factor receptor superfamily member 25 isoform X6

      UniProtKB/TrEMBL
      E1BHL8
      Conserved Domains (3) summary
      cd13420
      Location:62 → 175
      TNFRSF25; tumor necrosis factor receptor superfamily member 25 (TNFRSF25), also known as death receptor 3 (DR3)
      cl14633
      Location:326 → 402
      DD; Death Domain Superfamily of protein-protein interaction domains
      cl22855
      Location:168 → 200
      TNFRSF; Tumor necrosis factor receptor superfamily (TNFRSF)

    5. XM_005217150.5 → XP_005217207.1  tumor necrosis factor receptor superfamily member 25 isoform X3

      UniProtKB/TrEMBL
      A0A3Q1LIC4, E1BHL8
      Related
      ENSBTAP00070024036.1, ENSBTAT00070040504.1
      Conserved Domains (3) summary
      cd13420
      Location:62 → 175
      TNFRSF25; tumor necrosis factor receptor superfamily member 25 (TNFRSF25), also known as death receptor 3 (DR3)
      cl14633
      Location:362 → 438
      DD; Death Domain Superfamily of protein-protein interaction domains
      cl22855
      Location:168 → 200
      TNFRSF; Tumor necrosis factor receptor superfamily (TNFRSF)

    6. XM_005217151.5 → XP_005217208.1  tumor necrosis factor receptor superfamily member 25 isoform X4

      UniProtKB/TrEMBL
      E1BHL8
      Conserved Domains (3) summary
      cd13420
      Location:62 → 175
      TNFRSF25; tumor necrosis factor receptor superfamily member 25 (TNFRSF25), also known as death receptor 3 (DR3)
      cl14633
      Location:361 → 437
      DD; Death Domain Superfamily of protein-protein interaction domains
      cl22855
      Location:168 → 200
      TNFRSF; Tumor necrosis factor receptor superfamily (TNFRSF)
    Nucleotide Protein Strain
    Heading Accession and Version

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