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    ALS2CL ALS2 C-terminal like [ Bos taurus (domestic cattle) ]

    Gene ID: 506969, updated on 1-Jan-2025

    Summary

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    Official Symbol
    ALS2CLprovided by VGNC
    Official Full Name
    ALS2 C-terminal likeprovided by VGNC
    Primary source
    VGNC:VGNC:25852
    See related
    Ensembl:ENSBTAG00000017812
    Gene type
    protein coding
    RefSeq status
    PROVISIONAL
    Organism
    Bos taurus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Laurasiatheria; Artiodactyla; Ruminantia; Pecora; Bovidae; Bovinae; Bos
    Orthologs
    human mouse all
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    Genomic context

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    See ALS2CL in Genome Data Viewer
    Location:
    chromosome: 22
    Exon count:
    29
    Annotation release Status Assembly Chr Location
    RS_2024_12 current ARS-UCD2.0 (GCF_002263795.3) 22 NC_037349.1 (52793614..52815791)

    Chromosome 22 - NC_037349.1Genomic Context describing neighboring genes Neighboring gene serine protease 50 Neighboring gene transmembrane inner ear Neighboring gene vomeronasal 2 receptor 409 pseudogene Neighboring gene family with sequence similarity 240 member A

    Genomic regions, transcripts, and products

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    Genomic Sequence:
    NC_037349.1 Chromosome 22 Reference ARS-UCD2.0 Primary Assembly

    Go to nucleotide: Graphics FASTA GenBank

    Expression

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    • Project title: Dominette sequence data
    • BioProject: PRJNA294306
    • Analysis date: Tue Dec 17 08:57:05 2024

    Bibliography

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    Related articles in PubMed

    1. A whole-genome assembly of the domestic cow, Bos taurus. Zimin AV, et al. Genome Biol, 2009. PMID 19393038, Free PMC Article
    2. TreeGrafter: phylogenetic tree-based annotation of proteins with Gene Ontology terms and other annotations. Tang H, et al. Bioinformatics, 2019 Feb 1. PMID 30032202, Free PMC Article

    GeneRIFs: Gene References Into Functions

    General gene information

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    Homology

    Clone Names

    • MGC155060

    Gene Ontology Provided by RefSeq

    Function Evidence Code Pubs
    enables guanyl-nucleotide exchange factor activity IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    enables small GTPase binding IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    Process Evidence Code Pubs
    involved_in endosomal transport IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    involved_in regulation of GTPase activity IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    Component Evidence Code Pubs
    located_in cytoplasm IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    located_in cytoplasmic vesicle IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 

    General protein information

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    Preferred Names
    ALS2 C-terminal-like protein

    NCBI Reference Sequences (RefSeq)

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    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_001102488.1 → NP_001095958.1  ALS2 C-terminal-like protein

      See identical proteins and their annotated locations for NP_001095958.1

      Status: PROVISIONAL

      Source sequence(s)
      BC149185
      UniProtKB/Swiss-Prot
      A6QP75
      UniProtKB/TrEMBL
      A0A3Q1LIF8
      Related
      ENSBTAP00000023681.5, ENSBTAT00000023681.6
      Conserved Domains (4) summary
      COG4642
      Location:457 → 597
      COG4642; Uncharacterized conserved protein [Function unknown]
      pfam02204
      Location:834 → 938
      VPS9; Vacuolar sorting protein 9 (VPS9) domain
      pfam02493
      Location:358 → 378
      MORN; MORN repeat
      cl17171
      Location:223 → 321
      PH-like; Pleckstrin homology-like domain

    RefSeqs of Annotated Genomes: GCF_002263795.3-RS_2024_12

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference ARS-UCD2.0 Primary Assembly

    Genomic

    1. NC_037349.1 Reference ARS-UCD2.0 Primary Assembly

      Range
      52793614..52815791
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_059879550.1 → XP_059735533.1  ALS2 C-terminal-like protein isoform X3

      UniProtKB/TrEMBL
      A0A3Q1LIF8

    2. XM_059879548.1 → XP_059735531.1  ALS2 C-terminal-like protein isoform X1

      UniProtKB/TrEMBL
      A0A3Q1LIF8, A0A3Q1M2N1

    3. XM_059879547.1 → XP_059735530.1  ALS2 C-terminal-like protein isoform X1

      UniProtKB/TrEMBL
      A0A3Q1LIF8, A0A3Q1M2N1
      Related
      ENSBTAP00000067689.2, ENSBTAT00000073069.2

    4. XM_059879549.1 → XP_059735532.1  ALS2 C-terminal-like protein isoform X2

      UniProtKB/TrEMBL
      A0A3Q1LIF8

    5. XM_005223046.5 → XP_005223103.2  ALS2 C-terminal-like protein isoform X3

      UniProtKB/TrEMBL
      A0A3Q1LIF8
      Conserved Domains (3) summary
      pfam02204
      Location:843 → 947
      VPS9; Vacuolar sorting protein 9 (VPS9) domain
      cl17171
      Location:232 → 330
      PH-like; Pleckstrin homology-like domain
      cl27415
      Location:366 → 559
      COG4642; Uncharacterized conserved protein [Function unknown]

    6. XM_005223047.5 → XP_005223104.2  ALS2 C-terminal-like protein isoform X4

      UniProtKB/TrEMBL
      A0A3Q1LIF8
      Conserved Domains (2) summary
      cl17171
      Location:244 → 342
      PH-like; Pleckstrin homology-like domain
      cl27415
      Location:378 → 571
      COG4642; Uncharacterized conserved protein [Function unknown]
    Nucleotide Protein Strain
    Heading Accession and Version
    Protein Accession Links
    GenPept Link UniProtKB Link
    A6QP75.1 GenPept UniProtKB/Swiss-Prot:A6QP75

    Gene LinkOut

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