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    POLH DNA polymerase eta [ Bos taurus (domestic cattle) ]

    Gene ID: 513606, updated on 27-Dec-2024

    Summary

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    Official Symbol
    POLHprovided by VGNC
    Official Full Name
    DNA polymerase etaprovided by VGNC
    Primary source
    VGNC:VGNC:33124
    See related
    BGD:BT29397; Ensembl:ENSBTAG00000006015
    Gene type
    protein coding
    RefSeq status
    PROVISIONAL
    Organism
    Bos taurus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Laurasiatheria; Artiodactyla; Ruminantia; Pecora; Bovidae; Bovinae; Bos
    Orthologs
    human mouse all
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    Genomic context

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    See POLH in Genome Data Viewer
    Location:
    chromosome: 23
    Exon count:
    11
    Annotation release Status Assembly Chr Location
    RS_2024_12 current ARS-UCD2.0 (GCF_002263795.3) 23 NC_037350.1 (17114531..17143659)

    Chromosome 23 - NC_037350.1Genomic Context describing neighboring genes Neighboring gene Yip1 domain family member 3 Neighboring gene RNA polymerase I and III subunit C Neighboring gene exportin 5 Neighboring gene transfer RNA glutamic acid (anticodon UUC) Neighboring gene GTP binding protein 2 Neighboring gene MAD2L1 binding protein

    Genomic regions, transcripts, and products

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    Genomic Sequence:
    NC_037350.1 Chromosome 23 Reference ARS-UCD2.0 Primary Assembly

    Go to nucleotide: Graphics FASTA GenBank

    Expression

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    • Project title: Dominette sequence data
    • BioProject: PRJNA294306
    • Analysis date: Tue Dec 17 08:57:05 2024

    Bibliography

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    Related articles in PubMed

    1. Sequence evaluation of four pooled-tissue normalized bovine cDNA libraries and construction of a gene index for cattle. Smith TP, et al. Genome Res, 2001 Apr. PMID 11282978, Free PMC Article
    2. Characterization of 954 bovine full-CDS cDNA sequences. Harhay GP, et al. BMC Genomics, 2005 Nov 23. PMID 16305752, Free PMC Article
    3. A whole-genome assembly of the domestic cow, Bos taurus. Zimin AV, et al. Genome Biol, 2009. PMID 19393038, Free PMC Article
    4. Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. Strausberg RL, et al. Proc Natl Acad Sci U S A, 2002 Dec 24. PMID 12477932, Free PMC Article
    5. Manual GO annotation of predictive protein signatures: the InterPro approach to GO curation. Burge S, et al. Database (Oxford), 2012. PMID 22301074, Free PMC Article

    See all (6) citations in PubMed

    GeneRIFs: Gene References Into Functions

    General gene information

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    Homology

    Clone Names

    • MGC127832

    Gene Ontology Provided by RefSeq

    Function Evidence Code Pubs
    enables DNA-directed DNA polymerase activity IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    enables damaged DNA binding IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    Process Evidence Code Pubs
    involved_in error-prone translesion synthesis IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    involved_in response to radiation IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    Component Evidence Code Pubs
    located_in nucleus IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    located_in replication fork IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    located_in site of double-strand break IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 

    General protein information

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    Preferred Names
    DNA polymerase eta
    Names
    DNA-directed DNA polymerase eta
    polymerase (DNA directed), eta
    NP_001029622.1
    XP_059736291.1

    NCBI Reference Sequences (RefSeq)

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    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_001034450.1 → NP_001029622.1  DNA polymerase eta

      See identical proteins and their annotated locations for NP_001029622.1

      Status: PROVISIONAL

      Source sequence(s)
      BC103396
      UniProtKB/TrEMBL
      F1MZ79, Q3ZBE3
      Related
      ENSBTAP00000007900.5, ENSBTAT00000007900.6
      Conserved Domains (2) summary
      cd01702
      Location:10 → 428
      PolY_Pol_eta; DNA Polymerase eta
      COG0389
      Location:7 → 354
      DinP; Nucleotidyltransferase/DNA polymerase involved in DNA repair [Replication, recombination and repair]

    RefSeqs of Annotated Genomes: GCF_002263795.3-RS_2024_12

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference ARS-UCD2.0 Primary Assembly

    Genomic

    1. NC_037350.1 Reference ARS-UCD2.0 Primary Assembly

      Range
      17114531..17143659
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_059880308.1 → XP_059736291.1  DNA polymerase eta isoform X1

    Nucleotide Protein Strain
    Heading Accession and Version

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