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    SKA1 spindle and kinetochore associated complex subunit 1 [ Bos taurus (domestic cattle) ]

    Gene ID: 507703, updated on 27-Dec-2024

    Summary

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    Official Symbol
    SKA1provided by VGNC
    Official Full Name
    spindle and kinetochore associated complex subunit 1provided by VGNC
    Primary source
    VGNC:VGNC:34643
    See related
    Ensembl:ENSBTAG00000018216
    Gene type
    protein coding
    RefSeq status
    VALIDATED
    Organism
    Bos taurus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Laurasiatheria; Artiodactyla; Ruminantia; Pecora; Bovidae; Bovinae; Bos
    Orthologs
    human mouse all
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    Genomic context

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    See SKA1 in Genome Data Viewer
    Location:
    chromosome: 24
    Exon count:
    10
    Annotation release Status Assembly Chr Location
    RS_2024_12 current ARS-UCD2.0 (GCF_002263795.3) 24 NC_037351.1 (49964089..49995083)

    Chromosome 24 - NC_037351.1Genomic Context describing neighboring genes Neighboring gene methyl-CpG binding domain protein 1 Neighboring gene CXXC finger protein 1 Neighboring gene microRNA mir-2285cg Neighboring gene mitogen-activated protein kinase 4

    Genomic regions, transcripts, and products

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    Genomic Sequence:
    NC_037351.1 Chromosome 24 Reference ARS-UCD2.0 Primary Assembly

    Go to nucleotide: Graphics FASTA GenBank

    Expression

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    • Project title: Dominette sequence data
    • BioProject: PRJNA294306
    • Analysis date: Tue Dec 17 08:57:05 2024

    Bibliography

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    Related articles in PubMed

    1. A second generation radiation hybrid map to aid the assembly of the bovine genome sequence. Jann OC, et al. BMC Genomics, 2006 Nov 6. PMID 17087818, Free PMC Article
    2. Sequence evaluation of four pooled-tissue normalized bovine cDNA libraries and construction of a gene index for cattle. Smith TP, et al. Genome Res, 2001 Apr. PMID 11282978, Free PMC Article
    3. Characterization of 954 bovine full-CDS cDNA sequences. Harhay GP, et al. BMC Genomics, 2005 Nov 23. PMID 16305752, Free PMC Article
    4. A whole-genome assembly of the domestic cow, Bos taurus. Zimin AV, et al. Genome Biol, 2009. PMID 19393038, Free PMC Article
    5. Manual GO annotation of predictive protein signatures: the InterPro approach to GO curation. Burge S, et al. Database (Oxford), 2012. PMID 22301074, Free PMC Article

    See all (6) citations in PubMed

    GeneRIFs: Gene References Into Functions

    General gene information

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    Homology

    Gene Ontology Provided by RefSeq

    Function Evidence Code Pubs
    enables microtubule binding IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    Process Evidence Code Pubs
    involved_in cell division IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    involved_in chromosome segregation IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    involved_in mitotic cell cycle IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    involved_in regulation of microtubule polymerization or depolymerization IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    Component Evidence Code Pubs
    located_in mitotic spindle IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    part_of outer kinetochore IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    located_in spindle microtubule IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 

    General protein information

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    Preferred Names
    SKA complex subunit 1
    Names
    spindle and KT associated 1
    spindle and kinetochore-associated protein 1

    NCBI Reference Sequences (RefSeq)

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    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_001075327.2 → NP_001068795.2  SKA complex subunit 1

      See identical proteins and their annotated locations for NP_001068795.2

      Status: VALIDATED

      Source sequence(s)
      BT026543, CK971393, CO881184
      UniProtKB/Swiss-Prot
      G3X7D1, Q0V7M7
      UniProtKB/TrEMBL
      A0A3Q1NEK5
      Related
      ENSBTAP00000070061.1, ENSBTAT00000074446.2
      Conserved Domains (1) summary
      pfam07160
      Location:16 → 245
      SKA1; Spindle and kinetochore-associated protein 1

    RefSeqs of Annotated Genomes: GCF_002263795.3-RS_2024_12

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference ARS-UCD2.0 Primary Assembly

    Genomic

    1. NC_037351.1 Reference ARS-UCD2.0 Primary Assembly

      Range
      49964089..49995083
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_024984203.2 → XP_024839971.1  SKA complex subunit 1 isoform X1

      UniProtKB/Swiss-Prot
      G3X7D1, Q0V7M7
      UniProtKB/TrEMBL
      A0A3Q1NEK5
      Conserved Domains (1) summary
      pfam07160
      Location:16 → 245
      SKA1; Spindle and kinetochore-associated protein 1

    2. XM_005224135.5 → XP_005224192.1  SKA complex subunit 1 isoform X1

      See identical proteins and their annotated locations for XP_005224192.1

      UniProtKB/Swiss-Prot
      G3X7D1, Q0V7M7
      UniProtKB/TrEMBL
      A0A3Q1NEK5
      Conserved Domains (1) summary
      pfam07160
      Location:16 → 245
      SKA1; Spindle and kinetochore-associated protein 1

    3. XM_005224136.5 → XP_005224193.1  SKA complex subunit 1 isoform X1

      See identical proteins and their annotated locations for XP_005224193.1

      UniProtKB/Swiss-Prot
      G3X7D1, Q0V7M7
      UniProtKB/TrEMBL
      A0A3Q1NEK5
      Conserved Domains (1) summary
      pfam07160
      Location:16 → 245
      SKA1; Spindle and kinetochore-associated protein 1

    4. XM_059880780.1 → XP_059736763.1  SKA complex subunit 1 isoform X1

      UniProtKB/Swiss-Prot
      G3X7D1, Q0V7M7
      UniProtKB/TrEMBL
      A0A3Q1NEK5
      Related
      ENSBTAP00000024245.6, ENSBTAT00000024245.7
    Nucleotide Protein Strain
    Heading Accession and Version
    Protein Accession Links
    GenPept Link UniProtKB Link
    Q0V7M7.3 GenPept UniProtKB/Swiss-Prot:Q0V7M7

    Gene LinkOut

    The following LinkOut resources are supplied by external providers. These providers are responsible for maintaining the links.