U.S. flag

An official website of the United States government

Format

Send to:

Choose Destination

Links from GEO Profiles

    • Showing Current items.

    CRISP2 cysteine rich secretory protein 2 [ Bos taurus (domestic cattle) ]

    Gene ID: 512443, updated on 27-Dec-2024

    Summary

    Go to the top of the page Help
    Official Symbol
    CRISP2provided by VGNC
    Official Full Name
    cysteine rich secretory protein 2provided by VGNC
    Primary source
    VGNC:VGNC:53964
    See related
    BGD:BT25798; Ensembl:ENSBTAG00000002166
    Gene type
    protein coding
    RefSeq status
    PROVISIONAL
    Organism
    Bos taurus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Laurasiatheria; Artiodactyla; Ruminantia; Pecora; Bovidae; Bovinae; Bos
    Also known as
    TPX1; CRISP-1; CRISP-2
    Orthologs
    human mouse all
    NEW
    Try the new Gene table
    Try the new Transcript table

    Genomic context

    Go to the top of the page Help
    See CRISP2 in Genome Data Viewer
    Location:
    chromosome: 23
    Exon count:
    10
    Annotation release Status Assembly Chr Location
    RS_2024_12 current ARS-UCD2.0 (GCF_002263795.3) 23 NC_037350.1 (22413746..22439244, complement)

    Chromosome 23 - NC_037350.1Genomic Context describing neighboring genes Neighboring gene U6 spliceosomal RNA Neighboring gene Rh associated glycoprotein Neighboring gene uncharacterized LOC112443708 Neighboring gene cysteine-rich secretory protein 3 Neighboring gene eukaryotic translation elongation factor 1 alpha 1 pseudogene

    Genomic regions, transcripts, and products

    Go to the top of the page Help
    Genomic Sequence:
    NC_037350.1 Chromosome 23 Reference ARS-UCD2.0 Primary Assembly

    Go to nucleotide: Graphics FASTA GenBank

    Expression

    Go to the top of the page Help
    • Project title: Dominette sequence data
    • BioProject: PRJNA294306
    • Analysis date: Tue Dec 17 08:57:05 2024

    Bibliography

    Go to the top of the pageHelp

    Related articles in PubMed

    1. Association of CRISP2, CCT8, PEBP1 mRNA abundance in sperm and sire conception rate in Holstein bulls. Arangasamy A, et al. Theriogenology, 2011 Aug. PMID 21529916
    2. A whole-genome assembly of the domestic cow, Bos taurus. Zimin AV, et al. Genome Biol, 2009. PMID 19393038, Free PMC Article
    3. Manual GO annotation of predictive protein signatures: the InterPro approach to GO curation. Burge S, et al. Database (Oxford), 2012. PMID 22301074, Free PMC Article
    4. TreeGrafter: phylogenetic tree-based annotation of proteins with Gene Ontology terms and other annotations. Tang H, et al. Bioinformatics, 2019 Feb 1. PMID 30032202, Free PMC Article

    GeneRIFs: Gene References Into Functions

    What's a GeneRIF?
    1. CRISP2 mRNA levels are associated with male fertility.
      Title: Association of CRISP2, CCT8, PEBP1 mRNA abundance in sperm and sire conception rate in Holstein bulls.
    Submit: New GeneRIF Correction

    General gene information

    Go to the top of the page Help

    Homology

    Clone Names

    • MGC133685

    Gene Ontology Provided by RefSeq

    Component Evidence Code Pubs
    located_in extracellular region IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    located_in extracellular space IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 

    General protein information

    Go to the top of the page Help
    Preferred Names
    cysteine-rich secretory protein 2
    Names
    cysteine-rich secretory protein 1
    testis specific protein 1

    NCBI Reference Sequences (RefSeq)

    Go to the top of the page Help

    NEW Try the new Transcript table

    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_001038089.2 → NP_001033178.1  cysteine-rich secretory protein 2 precursor

      See identical proteins and their annotated locations for NP_001033178.1

      Status: PROVISIONAL

      Source sequence(s)
      BC109478
      UniProtKB/TrEMBL
      A0A3Q1N2J9, Q32LP8
      Related
      ENSBTAP00000002805.5, ENSBTAT00000002805.7
      Conserved Domains (2) summary
      cd05383
      Location:36 → 173
      SCP_CRISP; SCP_CRISP: SCP-like extracellular protein domain, CRISP-like sub-family. The wider family of SCP containing proteins includes plant pathogenesis-related protein 1 (PR-1), CRISPs, mammalian cysteine-rich secretory proteins, which combine SCP with a ...
      pfam08562
      Location:190 → 244
      Crisp; Crisp

    RefSeqs of Annotated Genomes: GCF_002263795.3-RS_2024_12

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference ARS-UCD2.0 Primary Assembly

    Genomic

    1. NC_037350.1 Reference ARS-UCD2.0 Primary Assembly

      Range
      22413746..22439244 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_024983543.2 → XP_024839311.1  cysteine-rich secretory protein 2 isoform X1

      UniProtKB/TrEMBL
      A0A3Q1N2J9, F1N2L7
      Related
      ENSBTAP00000063513.2, ENSBTAT00000075369.2
      Conserved Domains (3) summary
      cd05383
      Location:36 → 173
      SCP_CRISP; SCP_CRISP: SCP-like extracellular protein domain, CRISP-like sub-family. The wider family of SCP containing proteins includes plant pathogenesis-related protein 1 (PR-1), CRISPs, mammalian cysteine-rich secretory proteins, which combine SCP with a ...
      pfam08562
      Location:190 → 244
      Crisp; Crisp
      cl22415
      Location:5 → 52
      ESP; Exocrine gland-secreting peptide 1 (ESP1) and similar pheromones
    Nucleotide Protein Strain
    Heading Accession and Version

    Gene LinkOut

    The following LinkOut resources are supplied by external providers. These providers are responsible for maintaining the links.