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    PITPNA phosphatidylinositol transfer protein alpha [ Bos taurus (domestic cattle) ]

    Gene ID: 616550, updated on 27-Dec-2024

    Summary

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    Official Symbol
    PITPNAprovided by VGNC
    Official Full Name
    phosphatidylinositol transfer protein alphaprovided by VGNC
    Primary source
    VGNC:VGNC:32919
    See related
    BGD:BT17277; Ensembl:ENSBTAG00000011480
    Gene type
    protein coding
    RefSeq status
    PROVISIONAL
    Organism
    Bos taurus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Laurasiatheria; Artiodactyla; Ruminantia; Pecora; Bovidae; Bovinae; Bos
    Orthologs
    human mouse all
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    Genomic context

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    See PITPNA in Genome Data Viewer
    Location:
    chromosome: 19
    Exon count:
    12
    Annotation release Status Assembly Chr Location
    RS_2024_12 current ARS-UCD2.0 (GCF_002263795.3) 19 NC_037346.1 (22644897..22678492, complement)

    Chromosome 19 - NC_037346.1Genomic Context describing neighboring genes Neighboring gene inositol polyphosphate-5-phosphatase K Neighboring gene uncharacterized LOC132343030 Neighboring gene uncharacterized LOC112442780 Neighboring gene solute carrier family 43 member 2 Neighboring gene scavenger receptor class F member 1

    Genomic regions, transcripts, and products

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    Genomic Sequence:
    NC_037346.1 Chromosome 19 Reference ARS-UCD2.0 Primary Assembly

    Go to nucleotide: Graphics FASTA GenBank

    Expression

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    • Project title: Dominette sequence data
    • BioProject: PRJNA294306
    • Analysis date: Tue Dec 17 08:57:05 2024

    Bibliography

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    Related articles in PubMed

    1. An isoform of the phosphatidylinositol-transfer protein transfers sphingomyelin and is associated with the Golgi system. de Vries KJ, et al. Biochem J, 1995 Sep 1. PMID 7654206, Free PMC Article
    2. A whole-genome assembly of the domestic cow, Bos taurus. Zimin AV, et al. Genome Biol, 2009. PMID 19393038, Free PMC Article
    3. Manual GO annotation of predictive protein signatures: the InterPro approach to GO curation. Burge S, et al. Database (Oxford), 2012. PMID 22301074, Free PMC Article
    4. TreeGrafter: phylogenetic tree-based annotation of proteins with Gene Ontology terms and other annotations. Tang H, et al. Bioinformatics, 2019 Feb 1. PMID 30032202, Free PMC Article

    GeneRIFs: Gene References Into Functions

    General gene information

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    Homology

    Clone Names

    • MGC137921

    Gene Ontology Provided by RefSeq

    Function Evidence Code Pubs
    enables phosphatidylcholine binding IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    enables phosphatidylcholine transporter activity IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    enables phosphatidylinositol binding IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    enables phosphatidylinositol transfer activity IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    Process Evidence Code Pubs
    involved_in phospholipid transport IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    Component Evidence Code Pubs
    located_in cytoplasm IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 

    General protein information

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    Preferred Names
    phosphatidylinositol transfer protein alpha isoform
    Names
    PI-TP-alpha
    ptdIns transfer protein alpha
    ptdInsTP alpha

    NCBI Reference Sequences (RefSeq)

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    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_001046582.1 → NP_001040047.1  phosphatidylinositol transfer protein alpha isoform

      See identical proteins and their annotated locations for NP_001040047.1

      Status: PROVISIONAL

      Source sequence(s)
      BC113306
      UniProtKB/Swiss-Prot
      Q2HJ54, Q9TR37
      UniProtKB/TrEMBL
      A0A3Q1MUH4
      Related
      ENSBTAP00000082114.1, ENSBTAT00000116103.1
      Conserved Domains (1) summary
      cd08888
      Location:3 → 259
      SRPBCC_PITPNA-B_like; Lipid-binding SRPBCC domain of mammalian PITPNA, -B, and related proteins (Class I PITPs)

    RefSeqs of Annotated Genomes: GCF_002263795.3-RS_2024_12

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference ARS-UCD2.0 Primary Assembly

    Genomic

    1. NC_037346.1 Reference ARS-UCD2.0 Primary Assembly

      Range
      22644897..22678492 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)
    Nucleotide Protein Strain
    Heading Accession and Version
    Protein Accession Links
    GenPept Link UniProtKB Link
    Q2HJ54.3 GenPept UniProtKB/Swiss-Prot:Q2HJ54

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